CAZyme Information: FGRAMPH1_01T27217-p1

Basic Information

• Species: Fusarium graminearum
• Lineage: Ascomycota; Sordariomycetes; ; Nectriaceae; Fusarium; Fusarium graminearum
• CAZyme ID: FGRAMPH1_01T27217-p1
• CAZy Family: GT62
• CAZyme Description: GPI mannosyltransferase 1

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
422	HG970335|CGC25	47721.21	9.7134

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_FgraminearumPH-1	14145	229533	2	14143

• Gene Location: location=HG970335:6727544-6728915(+)

Full Sequence      

MPSIAPFLRTTPLFTISLLLRLGLLFYGIYQDAHSALKYTDIDYLVFTDASRFVADGQSP
YARDTYRYTPLLAWILLPTVRFPAFGKLVFAAADLLAGWLILRVLRRRGMDEATAGGFSA
LWLWNPMVATISTRGSSEGLLGVLTMGLLWAVDRRKFSLAAIILGLSVHFKIYPFIYAPA
IVWWMDDARLGKETKAAPQSSSIKDAVANFFTPDRLKFGLLSLITFMILNLVMFAIYETP
FLVHTYFHHVTRIDHRHNFSPYNVLLYLTSATPAHAAPAFRIESFAFLPQLLLSCVLIPL
ALAKRDLATSMMAQTFAFVTFNKVCTSQYFLWYMIFLPLYLPNSSFLRNGKLGIFALLLW
IVSQAAWLQQGYELEFLGISTFYPGLWLASIAFFLVNCWILGVIISDGARQSTRSTVKFH
VE

Enzyme Prediction     

EC	2.4.1.-:14

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT50	131	405	4e-97	0.9961832061068703

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
178434	PLN02841	1.03e-90	27	405	25	415	GPI mannosyltransferase
252941	Mannosyl_trans	7.31e-76	131	405	1	259	Mannosyltransferase (PIG-M). PIG-M has a DXD motif. The DXD motif is found in many glycosyltransferases that utilize nucleotide sugars. It is thought that the motif is involved in the binding of a manganese ion that is required for association of the enzymes with nucleotide sugar substrates.
399599	PIG-U	1.24e-06	55	236	45	227	GPI transamidase subunit PIG-U. Many eukaryotic proteins are anchored to the cell surface via glycosylphosphatidylinositol (GPI), which is posttranslationally attached to the carboxyl-terminus by GPI transamidase. The mammalian GPI transamidase is a complex of at least four subunits, GPI8, GAA1, PIG-S, and PIG-T. PIG-U is thought to represent a fifth subunit in this complex and may be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CEF84010.1|GT50	1.87e-306	1	422	1	422
CZS74519.1|GT50	1.87e-306	1	422	1	422
QPC63612.1|GT50	6.26e-305	1	422	1	422
QPC72495.1|GT50	2.55e-304	1	422	1	422
CEI40999.1|GT50	1.19e-293	1	422	1	422

PDB Hits     

FGRAMPH1_01T27217-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q4I073|GPI14_GIBZE	3.33e-307	1	422	1	422	GPI mannosyltransferase 1 OS=Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) OX=229533 GN=GPI14 PE=3 SV=1
sp|Q7S4Z3|GPI14_NEUCR	1.91e-172	7	410	23	487	GPI mannosyltransferase 1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=gim-1 PE=3 SV=1
sp|Q5B7W0|GPI14_EMENI	1.07e-163	20	407	18	427	GPI mannosyltransferase 1 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=gpi14 PE=3 SV=1
sp|Q2TXB8|GPI14_ASPOR	1.15e-163	7	411	5	413	GPI mannosyltransferase 1 OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=gpi14 PE=3 SV=2
sp|Q4WAH2|GPI14_ASPFU	6.60e-163	17	407	15	420	GPI mannosyltransferase 1 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=gpi14 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999993	0.000008

TMHMM  Annotations     

Start	End
7	29
80	102
162	184
220	242
285	302
317	339
346	368
383	405