CAZyme Information: EQL28863.1

Basic Information

• Species: Blastomyces dermatitidis
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Blastomyces; Blastomyces dermatitidis
• CAZyme ID: EQL28863.1
• CAZy Family: AA3
• CAZyme Description: alpha-1,3-mannosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
415	GL538514|CGC1	46624.21	9.9156

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_BdermatitidisATCC26199	9560	447095	380	9180

• Gene Location: location=GL538514:82574-84017(+)

Full Sequence      

MNIYERAVDLATNPKYSKWIWPLLLLAEVFLCTVIVWKVPYTEIDWSTYMQQVSLFLSGE
RDYALIKGSTGPLVYPAVHVYIYSALYHVCDDGRDIAFAQVIFAILYLATLVIVMWSYRS
AGAPPYLLPLLVLSKRLHSIFLLRLFNDAVATFFLWAAILMLQRRQWAVGVVLWSMGVGV
KMTVLLVAPAVAVIVVLGAGIIKAAGLGVTALLLQVLFAVPFLQDHPSSYISRAFEFTRQ
FLFTWTVNWRFVGEDVFLSKSFALALLVVHASILGAFFVFRWIAPSNTSLTQFINNIARG
KQSPTQITSSFIATTMLTSLAIGLLCARSLHYQFFAYLSWATPFLLWKSGFHPLLIYLLW
TAQEWAWNVYPSTTISSITIVACLAIQVLGSFLNGFERVPKRTQGLKGGLAMSRR

Enzyme Prediction     

EC	2.4.1.258:10

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT58	22	377	1.8e-144	0.9945054945054945

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
398745	ALG3	0.0	22	377	1	358	ALG3 protein. The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl pyrophosphate. Whereas early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9GlcNAc2-PP-Dol on the lumenal side use Dol-P-Man. ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS72893.1|GT58	3.73e-241	1	397	1	397
QSS55330.1|GT58	1.07e-240	1	397	1	397
QSS65569.1|GT58	1.15e-206	50	395	1	346
QVM12997.1|GT58	1.56e-178	1	394	1	394
BCR98022.1|GT58	7.14e-177	9	408	9	408

PDB Hits     

EQL28863.1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q2U6A4|ALG3_ASPOR	2.08e-176	9	405	9	408	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=alg3 PE=3 SV=1
sp|Q4WVG2|ALG3_ASPFU	1.42e-168	1	398	9	406	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=alg3 PE=3 SV=1
sp|A1DDZ3|ALG3_NEOFI	3.61e-162	1	398	1	398	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=alg3 PE=3 SV=1
sp|A1CBE6|ALG3_ASPCL	3.37e-160	9	403	71	466	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=alg3 PE=3 SV=1
sp|A2RA94|ALG3_ASPNC	2.60e-154	9	394	9	390	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=alg3 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000033	0.000003

TMHMM  Annotations     

Start	End
19	41
72	89
96	118
140	162
169	191
201	223
263	285
305	327
334	356
371	393