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CAZyme Information: EPrPVT00000021447-p1

You are here: Home > Sequence: EPrPVT00000021447-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phytopythium vexans
Lineage Oomycota; NA; ; Pythiaceae; Phytopythium; Phytopythium vexans
CAZyme ID EPrPVT00000021447-p1
CAZy Family GH78
CAZyme Description General transcription factor IIH subunit
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
950 101649.76 4.9279
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_PvexansDAOMBR484 11991 1223560 34 11957
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in EPrPVT00000021447-p1.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH17 41 294 2.9e-22 0.9453376205787781

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
237285 trpA 7.47e-108 723 950 1 228
tryptophan synthase subunit alpha; Provisional
240075 Tryptophan_synthase_alpha 2.93e-98 735 950 1 215
Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both strongly stimulated by the formation of the complex. The alpha subunit catalyzes the cleavage of indole 3-glycerol phosphate (IGP) to indole and d-glyceraldehyde 3-phosphate (G3P). Indole is then channeled to the active site of the beta subunit, a PLP-dependent enzyme that catalyzes a replacement reaction to convert L-serine into L-tryptophan.
223237 TrpA 1.59e-93 721 950 4 233
Tryptophan synthase alpha chain [Amino acid transport and metabolism].
397778 Tfb4 7.27e-92 415 671 3 273
Transcription factor Tfb4. This family appears to be distantly related to the VWA domain.
395227 Trp_syntA 2.48e-89 725 950 1 226
Tryptophan synthase alpha chain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
4.39e-74 11 306 10 304
9.73e-72 5 304 5 310
3.50e-71 16 304 19 313
1.11e-70 2 306 1 315
3.57e-67 8 303 1 313

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.85e-67 721 950 4 233
Lbcats [synthetic construct],5EY5_C Lbcats [synthetic construct]
3.13e-55 415 690 10 305
Human core TFIIH bound to DNA within the PIC [Homo sapiens],5IY6_3 Human holo-PIC in the closed state [Homo sapiens],5IY7_3 Chain 3, General transcription factor IIH subunit 3 [Homo sapiens],5IY8_3 Human holo-PIC in the initial transcribing state [Homo sapiens],5IY9_3 Human holo-PIC in the initial transcribing state (no IIS) [Homo sapiens],5O85_A p34-p44 complex [Homo sapiens],5O85_C p34-p44 complex [Homo sapiens],5OF4_F Chain F, General transcription factor IIH subunit 3 [Homo sapiens],6NMI_F Cryo-EM structure of the human TFIIH core complex [Homo sapiens],6O9L_4 Human holo-PIC in the closed state [Homo sapiens],6O9M_4 Structure of the human apo TFIIH [Homo sapiens],6RO4_E Structure of the core TFIIH-XPA-DNA complex [Homo sapiens],7AD8_E Chain E, General transcription factor IIH subunit 3 [Homo sapiens],7EGB_3 Chain 3, General transcription factor IIH subunit 3 [Homo sapiens],7EGC_3 Chain 3, General transcription factor IIH subunit 3 [Homo sapiens],7ENA_3 Chain 3, General transcription factor IIH subunit 3 [Homo sapiens],7ENC_3 Chain 3, General transcription factor IIH subunit 3 [Homo sapiens],7LBM_b Chain b, General transcription factor IIH subunit 3 [Homo sapiens],7NVR_4 Chain 4, General transcription factor IIH subunit 3 [Homo sapiens],7NVW_4 Chain 4, General transcription factor IIH subunit 3 [Homo sapiens],7NVX_4 Chain 4, General transcription factor IIH subunit 3 [Homo sapiens],7NVY_4 Chain 4, General transcription factor IIH subunit 3 [Homo sapiens],7NVZ_4 Chain 4, General transcription factor IIH subunit 3 [Homo sapiens],7NW0_4 Chain 4, General transcription factor IIH subunit 3 [Homo sapiens]
4.09e-49 721 950 7 236
Crystal structure of Tryptophan synthase alpha chain from Legionella pneumophila subsp. pneumophila [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
1.04e-48 721 950 7 236
Crystal structure of tryptophan synthase subunit alpha from Legionella pneumophila str. Paris [Legionella pneumophila str. Paris]
1.29e-46 735 950 6 220
Chain A, Tryptophan synthase alpha chain [Pyrococcus furiosus],2DZP_B Chain B, Tryptophan synthase alpha chain [Pyrococcus furiosus]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2.67e-65 721 950 4 234
Tryptophan synthase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=trp-3 PE=1 SV=1
9.15e-65 719 950 3 235
Tryptophan synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TRP5 PE=1 SV=1
5.00e-62 721 948 4 231
Tryptophan synthase alpha chain OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95) OX=316274 GN=trpA PE=3 SV=1
6.54e-61 721 949 4 232
Tryptophan synthase alpha chain OS=Roseiflexus castenholzii (strain DSM 13941 / HLO8) OX=383372 GN=trpA PE=3 SV=1
1.24e-60 721 949 4 232
Tryptophan synthase alpha chain OS=Roseiflexus sp. (strain RS-1) OX=357808 GN=trpA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000380 0.999592 CS pos: 19-20. Pr: 0.9692

TMHMM  Annotations      help

There is no transmembrane helices in EPrPVT00000021447-p1.