CAZyme Information: EPrPVT00000018418-p1

Basic Information

• Species: Phytopythium vexans
• Lineage: Oomycota; NA; ; Pythiaceae; Phytopythium; Phytopythium vexans
• CAZyme ID: EPrPVT00000018418-p1
• CAZy Family: PL1
• CAZyme Description: Glycosyltransferase protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
429	PvexDAOMBR484_SC0298|CGC1	48116.52	7.5658

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PvexansDAOMBR484	11991	1223560	34	11957

• Gene Location: location=PvexDAOMBR484_SC0298:25862-27325(+)

Full Sequence      

MGEASGSAFVLRACIFLLLLIVSLVQLAFFTLLPDVSIHAEWCNATLAARSPAGRAPTSP
ELAPPLRLLYQSLYLSPREIARREKEAERLEAARKLDLELYLGALPSARPVVIGPGPTEP
VELPTSVINIFLQRHPSNTQYFGSALKHQPAEKAVWMLQNAELFDRHELSSPPVGVVMVK
NRVALQKVLEYRHRHQLSYSALYTKHTGHDVFQPSMQRDWTSFLHVPGASPAKTTKVIVQ
AWAAHPEWPKLVLRVAQPELCHWISRHFGSATSWRLANVDFQCGRLAEADKAALQNQIGL
HVCPSEGEAFSHVLNEARSAGALILTTDVAPMNELVDRESGVLVGQPTTWWWQTKGDLFM
PLGRVDMAAIEQGVEQILLLPVEERRRMGRRARAHYLEDRAFFLNAMAALEQAICQDEIR
IDKLQPYLY

Enzyme Prediction     

No EC number prediction in EPrPVT00000018418-p1.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
340831	GT4_PimA-like	1.82e-07	223	344	195	314	phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
223515	RfaB	2.20e-04	278	344	258	324	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
340816	Glycosyltransferase_GTB-type	3.26e-04	191	344	81	235	glycosyltransferase family 1 and related proteins with GTB topology. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
404563	Glyco_trans_1_4	3.51e-04	289	344	65	120	Glycosyl transferases group 1.
340836	GT4_WbnK-like	5.06e-04	290	344	257	311	Shigella dysenteriae WbnK and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CCA20002.1|GT4	2.09e-154	5	429	10	470
UIZ29740.1|GT4	5.57e-154	96	429	122	468
QHB73863.1|GT4	3.60e-30	196	410	114	312
CAG4968350.1|GT4	1.06e-29	222	409	143	315
UOV06796.1|GT4	1.24e-28	150	409	10	248

PDB Hits     

EPrPVT00000018418-p1 has no PDB hit.

Swiss-Prot Hits     

EPrPVT00000018418-p1 has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000005	0.000008

TMHMM  Annotations     

Start	End
7	29