CAZyme Information: EPrPVT00000016608-p1

Basic Information

• Species: Phytopythium vexans
• Lineage: Oomycota; NA; ; Pythiaceae; Phytopythium; Phytopythium vexans
• CAZyme ID: EPrPVT00000016608-p1
• CAZy Family: GH123
• CAZyme Description: Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit STT3A

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
851		95024.45	7.4899

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PvexansDAOMBR484	11991	1223560	34	11957

• Gene Location: location=PvexDAOMBR484_SC0151:23187-26046(+)

Full Sequence      

MMRNVVFGVDLDSPHDADDEANVLAPTAKFAILGMICLMSFAIRLFAVVRYESVIHEFDP
YFNYRTTKYLASEGFLEFLDWFDDRAWYPLGRIIGGTIYPGLMYTAAMVYWVLNLLNISI
NVRNTCVFLAPVFAANTAIASYLLTKEVTKRSSAGLLAAAFAGIVPSYISRSVGGSYDNE
GVAIFALIFVFYLWIKAVHTGSMFWSASCALAYFYMVAAWGGYVFIINMIPIYVLVMIFA
GRYTPRLYIAYSTFYTLGSLMAMQVPFVGFNVIKQAECAGSHGVFVLLQVYCFVNWLRNY
ISAASFRRLVIYGASLVVVIVASALVVLQLLGKVQWTGRSLTLLDPTYASKYIPIIASVS
EHQPTTWTSYFFDLHVLVPFAPVGLYFLFTNLTDGGIFVILYGTVAWYFAGVMVRLMLTL
APIACILGAIGISSTLRKFMGILRRPSTYVIQKNGVQEVPMPLAMLVVGGLLVMLLSYTF
HATYVSSMAYSSPSIVIEAGRTHTGERVNFDDYREAYFWLRQNTDANAKIMSWWDYGYQM
SAMANRTVLVDNNTWNNTHIATVGRALASSEEDAYPIMQSLDVDYVLVIFGGVTGYSSDD
INKFLWPVRIGSGVYPDDMPGERDYYSSSGNFDIGPGGSKVLHNCLAYKLCYYRFGEVVT
DYQRPPGFDRARNTEVGVKNIKLTHLEEAFTSEHWIVRIFKVKKQANVEATKAVKQARIH
EAEAPENDISQEKTHFWGCVTGEDMLGNDRVYAGGASGANYNLALHHAKEKGKKYFALSR
VGSEGHAFAFNKLPQHPKDFDGNDDGCRRPCLDSNAHSCGCADGGCVDMNVRPGRGQEHN
RRWAIYERIQA

Enzyme Prediction     

EC	2.4.99.18:21

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT66	30	659	1.3e-170	0.8513708513708513

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396873	STT3	1.76e-108	29	491	3	478	Oligosaccharyl transferase STT3 subunit. This family consists of the oligosaccharyl transferase STT3 subunit and related proteins. The STT3 subunit is part of the oligosaccharyl transferase (OTase) complex of proteins and is required for its activity. In eukaryotes, OTase transfers a lipid-linked core-oligosaccharide to selected asparagine residues in the ER. In the archaea STT3 occurs alone, rather than in an OTase complex, and is required for N-glycosylation of asparagines.
224206	Stt3	3.14e-65	29	704	18	731	Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, protein turnover, chaperones].
275016	archaeo_STT3	8.99e-21	30	588	1	586	oligosaccharyl transferase, archaeosortase A system-associated. Members of this protein family occur, one to three members per genome, in the same species of Euryarchaeota as contain the predicted protein-sorting enzyme archaeosortase (TIGR04125) and its cognate protein-sorting signal PGF-CTERM (TIGR04126).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UIZ23018.1|GT66	0.0	6	849	40	883
CCA15036.1|GT66	0.0	18	850	51	881
CCA23157.1|GT66	0.0	18	850	51	881
AFJ69334.1|GT66	0.0	18	847	53	890
ACI33169.1|GT66	3.96e-280	29	707	19	699

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6FTG_5	8.97e-280	29	707	19	699	Subtomogram average of OST-containing ribosome-translocon complexes from canine rough microsomal membranes [Canis lupus familiaris],6FTI_5 Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S Ribosome [Canis lupus familiaris]
6FTJ_5	9.23e-280	29	703	19	695	Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Non-programmed 80S Ribosome [Canis lupus familiaris]
6S7O_A	2.55e-279	29	707	19	699	Cryo-EM structure of human oligosaccharyltransferase complex OST-A [Homo sapiens]
6S7T_A	1.63e-267	29	709	73	779	Cryo-EM structure of human oligosaccharyltransferase complex OST-B [Homo sapiens]
6C26_A	1.51e-215	22	704	10	684	The Cryo-EM structure of a eukaryotic oligosaccharyl transferase complex [Saccharomyces cerevisiae S288C],6EZN_F Cryo-EM structure of the yeast oligosaccharyltransferase (OST) complex [Saccharomyces cerevisiae S288C],7OCI_F Chain F, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 [Saccharomyces cerevisiae S288C]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|F1PJP5|STT3A_CANLF	2.30e-279	29	707	19	699	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Canis lupus familiaris OX=9615 GN=STT3A PE=1 SV=3
sp|P46978|STT3A_MOUSE	2.30e-279	29	707	19	699	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Mus musculus OX=10090 GN=Stt3a PE=1 SV=1
sp|P46977|STT3A_HUMAN	1.31e-278	29	707	19	699	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2
sp|Q5RCE2|STT3A_PONAB	1.31e-278	29	707	19	699	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Pongo abelii OX=9601 GN=STT3A PE=2 SV=1
sp|Q2KJI2|STT3A_BOVIN	3.02e-277	29	707	19	699	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Bos taurus OX=9913 GN=STT3A PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000016	0.000006

TMHMM  Annotations     

Start	End
21	43
91	113
126	145
155	174
181	203
218	240
247	269
279	297
309	331
367	389
396	413
417	436
463	485