CAZyme Information: EPrPVT00000014008-p1

Basic Information

• Species: Phytopythium vexans
• Lineage: Oomycota; NA; ; Pythiaceae; Phytopythium; Phytopythium vexans
• CAZyme ID: EPrPVT00000014008-p1
• CAZy Family: AA17
• CAZyme Description: Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
496		56257.15	9.2459

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_PvexansDAOMBR484	11991	1223560	34	11957

• Gene Location: location=PvexDAOMBR484_SC0024:57425-58998(-)

Full Sequence      

MQQVALYKGGERDYVNIKGDTGPLVYPAGFLYVYSVLHSLTDGGENIRRAQYIFLGFYLA
TIATVLAIYYRARVMPPWAAVFLLVSKRLHSIYMLRMFNDGVAMMLLFMAVYLFARQRWR
WGCVLFSCAVSIKMNVLLFAPALFFLLLQSCGVLRTVWYLFICAAIQIALGYPFLRENWA
SYMSKAFELSRVFTYKWTVNWRFLPEDIFVSKQLALLLLGLHLFFLVLFLNKHFAIIGTF
RAVLYKPFAIYQPFPIRSEVVVTSLFVINFVGVCFSRTMHYQFYSWYFPTLPYLLWKTNL
PLLLRIKALLLSEYAFNTFPATNVSSMLLQATNIFILLSLYFSEDRGLVVPYLDADSRVN
LIAFVNEECFDGARQLAMYYGSVTEDLAQGASMTSIDEREVVLSLPKLKLTLAVGFGSSA
PVTSEGYGRTVLRGMLAEATEGLAAGDTMGKVISREYMKEKELSELVDGIEEKNRAVSEA
KTAAALRHRAGNASSV

Enzyme Prediction     

EC	2.4.1.258:18

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT58	1	326	1.6e-122	0.9175824175824175

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
398745	ALG3	1.30e-161	1	326	29	358	ALG3 protein. The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl pyrophosphate. Whereas early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9GlcNAc2-PP-Dol on the lumenal side use Dol-P-Man. ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UIZ28023.1|GT58	1.56e-262	1	478	76	553
CCA23790.1|GT58	4.81e-234	1	489	74	555
AWP04161.1|GT58	3.06e-96	1	343	86	434
SVE76345.1|GT58	6.59e-95	1	341	78	413
SVE85454.1|GT58	6.59e-95	1	360	78	427

PDB Hits     

EPrPVT00000014008-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q55F69|ALG3_DICDI	1.08e-97	1	342	51	423	Probable Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Dictyostelium discoideum OX=44689 GN=alg3 PE=3 SV=1
sp|Q8K2A8|ALG3_MOUSE	6.34e-91	1	345	75	425	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Mus musculus OX=10090 GN=Alg3 PE=1 SV=2
sp|Q92685|ALG3_HUMAN	1.96e-89	1	345	75	425	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG3 PE=1 SV=1
sp|O82244|ALG3_ARATH	8.56e-88	1	352	65	424	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Arabidopsis thaliana OX=3702 GN=ALG3 PE=1 SV=1
sp|P82149|NT53_DROME	5.68e-76	1	334	78	478	Lethal(2)neighbour of tid protein 2 OS=Drosophila melanogaster OX=7227 GN=l(2)not2 PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999995	0.000029

TMHMM  Annotations     

Start	End
23	40
53	72
92	114
121	143
153	175
217	239
254	276
283	305
320	342