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CAZyme Information: EPrPRT00000023468-p1

You are here: Home > Sequence: EPrPRT00000023468-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Pythium arrhenomanes
Lineage Oomycota; NA; ; Pythiaceae; Pythium; Pythium arrhenomanes
CAZyme ID EPrPRT00000023468-p1
CAZy Family GT20
CAZyme Description Di-N-acetylchitobiase.
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
389 44287.64 6.4926
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_ParrhenomanesATCC12531 13857 1223556 52 13805
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.-:18

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 80 367 3.3e-39 0.777027027027027

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
119354 GH18_chitobiase 3.49e-111 36 385 11 358
Chitobiase (also known as di-N-acetylchitobiase) is a lysosomal glycosidase that hydrolyzes the reducing-end N-acetylglucosamine from the chitobiose core of oligosaccharides during the ordered degradation of asparagine-linked glycoproteins in eukaryotes. Chitobiase can only do so if the asparagine that joins the oligosaccharide to protein is previously removed by a glycosylasparaginase. Chitobiase is therefore the final step in the lysosomal degradation of the protein/carbohydrate linkage component of asparagine-linked glycoproteins. The catalytic domain of chitobiase is an eight-stranded alpha/beta barrel fold similar to that of other family 18 glycosyl hydrolases such as hevamine and chitotriosidase.
214753 Glyco_18 2.17e-31 123 368 88 333
Glyco_18 domain.
395573 Glyco_hydro_18 6.01e-24 101 367 58 305
Glycosyl hydrolases family 18.
119353 GH18_CFLE_spore_hydrolase 1.01e-22 69 364 32 300
Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
226376 YaaH 7.26e-16 121 364 186 405
Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
2.11e-138 25 389 448 837
4.41e-128 41 389 3 356
5.85e-128 36 389 27 385
5.38e-102 32 373 15 366
2.40e-78 43 385 24 362

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2.54e-09 132 373 98 346
Crystal structure of a insect group III chitinase (CAD2) from Ostrinia furnacalis [Ostrinia furnacalis],5WVH_A Crystal structure of an insect group III chitinase complex with (GlcNAc)6 (CAD2-(GlcNAc)6) from Ostrinia furnacalis [Ostrinia furnacalis]
2.47e-08 132 373 98 346
Crystal structure of a mutant insect group III chitinase (CAD2-E647L) from Ostrinia furnacalis [Ostrinia furnacalis],5WVG_A Crystal structure of a mutant insect group III chitinase complex with (GlcNAc)5 (CAD1-E647L-(GlcNAc)5) from Ostrinia furnacalis [Ostrinia furnacalis]
2.28e-07 197 364 261 408
Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_B Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_C Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876]
2.93e-06 183 364 246 410
Chain A, Spore germination protein YaaH [Priestia megaterium QM B1551]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6.31e-76 29 386 9 363
Di-N-acetylchitobiase OS=Mus musculus OX=10090 GN=Ctbs PE=1 SV=2
1.21e-74 44 386 41 379
Di-N-acetylchitobiase OS=Homo sapiens OX=9606 GN=CTBS PE=1 SV=1
4.04e-74 20 385 2 363
Di-N-acetylchitobiase OS=Rattus norvegicus OX=10116 GN=Ctbs PE=1 SV=1
3.86e-53 44 389 26 374
Probable di-N-acetylchitobiase 2 OS=Dictyostelium discoideum OX=44689 GN=ctbs2 PE=3 SV=1
8.49e-52 42 389 21 370
Probable di-N-acetylchitobiase 1 OS=Dictyostelium discoideum OX=44689 GN=ctbs1 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
0.713995 0.286003

TMHMM  Annotations      help

There is no transmembrane helices in EPrPRT00000023468-p1.