CAZyme Information: EPrPIT00000018154-p1

Basic Information

• Species: Globisporangium irregulare
• Lineage: Oomycota; NA; ; Pythiaceae; Globisporangium; Globisporangium irregulare
• CAZyme ID: EPrPIT00000018154-p1
• CAZy Family: GH16
• CAZyme Description: Alpha

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1249		139406.09	4.6300

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_GirregulareDAOMBR486	13869	1223557	65	13804

• Gene Location: location=PirrDAOMBR486_SC0293:7895-11644(+)

Full Sequence      

MTMGTDSPDAQTPPQETQLELSFKDKEKGLLSELAALYTKLNQVREKRVKAEEESSRGGN
GTDAGSAFDDESVGGKSRKRRRVLLVTRSLPFTLVWEEAQSQWRAEFPENVSLDGAMETF
MSMHENYDCVWIGSVHGDIEPSEQNSLKEQLLEDRNYYPVFLDPKRERLFYNGFCKTVMW
PLFHSCPPTTDDQLSTHEMDTSSYGEDDFDMDKMWQAYVSANQAFADAIQEVYEEGDLVW
IQGYHLTLVPQMVQNLFPNDNIDVGFFMHIPFPSSELYRIMNNREEILTGMLGADLVGFQ
TYEYARHFQSSAVRLLGLESSHKGVEYNGHFTRVTICPVGIDADKYTSLVSTNGVQEQIK
QLMNQFAGKKVILGVDPLDITKGLVHKLLAVEELFTTHPELSKEVVFLQIVTGTPSLFES
PLGSQVESLVSRINSKLQDIGADGPVQYLNKEIPQEALIALYSLADTLVVTPIRDGMNTI
PFEYVVCREAHGKHARVVLSEFAGSAHSLGGAALVNPWDTEDLLAALLASLQENDDVMRA
HQSMYSYVRTFTSKHWADNFLEQLRECSEENALAVSGRELSRRDMTSAYIRSSRRLIFIT
YEGVLAAEASIPELSYPPQELIWQLSMLTKDPRNTVVLVCARSTAVCEQWFAGLTGNIVL
AAEYGVYVKWVGEHEYWHCMVPNMDMSWWEHVVPLLEYYTERTPGAFIERKDSSVAWHYR
DCDLDHGLWQASELLVSLRELTRSLPVAVCPGNRVLEVRPQKASKAWLFERIWEFMNYSI
LFPEESPVTTDYFGDPVKPLSSPLATPWSGGADGNDWQKESHLTPLHLGGKGGNKDDTPE
SSGNGGGSDDESERVHSSEFQPVDFLLVIASGEDRTDEDLFAYLVPAPIDLEAYCRQLEK
DQQFDSLSEHQFGGFPGHDEEGQRSSFRRIPLNDSGAADSAISSTFEETKRLSPRGSFRR
LMGLDSDGSSNAENSGHPELLAPALARIPSSGPDGDFLLLGENITKLTPLHGSKQAISDD
AANMFPRTMLNTPTNARRDEITERSKFTPRRDFPPSAALFKAMKSKYGENFSMHRLPDTP
AAAWALVVPPNARAKLEDPSASPQILSSSSGMDRKASFNSSAVAIAGSPTSTSNFEGGAG
GSVTSDSYGSYSSPSASMVDGDEQMRREIEALRSLDEDVTLHTSETNDEVEAQYRFPVNT
FVCTLGRKLSQAPYFIKNSADLYQLLQEMGLNSHIRKQRMMSMGSHLDE

Enzyme Prediction     

EC	2.4.1.15:146

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT20	76	565	2.3e-148	0.9810526315789474

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
184712	PRK14501	0.0	82	765	2	658	putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional
340820	GT20_TPS	1.33e-163	82	565	1	463	trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.
395781	Glyco_transf_20	6.49e-149	82	564	2	468	Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex,.
215556	PLN03064	2.89e-147	60	772	71	776	alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional
215555	PLN03063	2.09e-142	79	772	9	686	alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UIZ28038.1|GT20	0.0	22	1245	6	1241
CCA15235.1|GT20	0.0	24	1242	28	1218
QOX06485.1|GT20	3.60e-159	18	782	10	760
AJA04606.1|GT20	1.01e-158	30	772	68	806
AGT80036.1|GT20	1.01e-158	30	772	68	806

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5HVM_A	1.40e-94	72	572	3	482	Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVM_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]
5HUV_A	1.74e-94	82	573	5	476	Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314],5HUV_B Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314]
5HUT_A	2.40e-94	82	573	5	476	Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUT_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUU_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HUU_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HVL_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314],5HVL_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314]
5HVO_A	1.18e-92	82	568	12	478	Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_C Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_D Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]
6JBI_A	8.14e-88	82	564	1	462	Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBI_B Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBR_A Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_B Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_D Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_F Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_H Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_K Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_M Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_O Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBW_A Structure of Tps1/UDP complex [Pyricularia oryzae 70-15],6JBW_B Structure of Tps1/UDP complex [Pyricularia oryzae 70-15]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q54K57|TPSA_DICDI	1.37e-146	82	759	17	660	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] A OS=Dictyostelium discoideum OX=44689 GN=tpsA PE=2 SV=1
sp|Q54NU9|TPSB_DICDI	5.59e-133	116	772	83	725	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] B OS=Dictyostelium discoideum OX=44689 GN=tpsB PE=3 SV=1
sp|Q9LRA7|TPS9_ARATH	4.41e-130	63	772	41	765	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 9 OS=Arabidopsis thaliana OX=3702 GN=TPS9 PE=2 SV=1
sp|Q0WUI9|TPS8_ARATH	4.63e-130	63	772	41	760	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8 OS=Arabidopsis thaliana OX=3702 GN=TPS8 PE=2 SV=1
sp|O80738|TPS10_ARATH	7.56e-124	80	784	58	777	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 10 OS=Arabidopsis thaliana OX=3702 GN=TPS10 PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000041	0.000000

TMHMM  Annotations     

There is no transmembrane helices in EPrPIT00000018154-p1.