CAZyme Information: EJT79714.1

Basic Information

• Species: Gaeumannomyces tritici
• Lineage: Ascomycota; Sordariomycetes; ; Magnaporthaceae; Gaeumannomyces; Gaeumannomyces tritici
• CAZyme ID: EJT79714.1
• CAZy Family: GH78
• CAZyme Description: Peroxidase [Source:UniProtKB/TrEMBL;Acc:J3NU46]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
363		38380.34	8.8344

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_GtriticiR3-111a-1	14749	644352	291	14458

• Gene Location: location=GL385396:6592030-6593360(-)

Full Sequence      

MGPYHPSHLLASVRSTIPTRLPTLTFARSSLPCCATRNRAFRFPSWQSNLPLSTMRLSIT
LVLPSLLALAGAVPGPKGGDDSGKSGTRGDDGGRGGGSGKCPEVWGAVKAELNQKFMTGT
ECNGLARAAIRAIFHDCGSWDQSQGLVGGCDGSLITGVTPDVELDRPENRGLQTVAAYLK
DAAARHGTSVADMIVFAGNAATVLCPGGPRVKTFIGRKDSTNSAKPGGLPDVFDTAANLV
DLFAKKGYSQAELAALMGAHSTSTQRFVDPSQAGKAQDSTPGQWDVKYYKETIDYAKTGK
TPNNVFVFPSDAKLATYQDVGKKFEGFVNNQNKWSSAFGNAMEKMALFGNDKNNMVDCTN
ALG

Enzyme Prediction     

No EC number prediction in EJT79714.1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA2	107	350	9e-58	0.984313725490196

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
173826	ligninase	1.66e-83	104	362	16	287	Ligninase and other manganese-dependent fungal peroxidases. Ligninases and related extracellular fungal peroxidases belong to class II of the plant heme-dependent peroxidase superfamily. All members of the superfamily share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Class II peroxidases are fungal glycoproteins that have been implicated in the oxidative breakdown of lignin, the main cell wall component of woody plants. They contain four conserved disulphide bridges and two conserved calcium binding sites.
173823	plant_peroxidase_like	2.57e-34	107	345	2	253	Heme-dependent peroxidases similar to plant peroxidases. Along with animal peroxidases, these enzymes belong to a group of peroxidases containing a heme prosthetic group (ferriprotoporphyrin IX), which catalyzes a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. The plant peroxidase-like superfamily is found in all three kingdoms of life and carries out a variety of biosynthetic and degradative functions. Several sub-families can be identified. Class I includes intracellular peroxidases present in fungi, plants, archaea and bacteria, called catalase-peroxidases, that can exhibit both catalase and broad-spectrum peroxidase activities depending on the steady-state concentration of hydrogen peroxide. Catalase-peroxidases are typically comprised of two homologous domains that probably arose via a single gene duplication event. Class II includes ligninase and other extracellular fungal peroxidases, while class III is comprised of classic extracellular plant peroxidases, like horseradish peroxidase.
173827	secretory_peroxidase	6.21e-31	101	345	11	278	Horseradish peroxidase and related secretory plant peroxidases. Secretory peroxidases belong to class III of the plant heme-dependent peroxidase superfamily. All members of the superfamily share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Class III peroxidases are found in the extracellular space or in the vacuole in plants where they have been implicated in hydrogen peroxide detoxification, auxin catabolism and lignin biosynthesis, and stress response. Class III peroxidases contain four conserved disulphide bridges and two conserved calcium binding sites.
395089	peroxidase	1.07e-30	108	261	1	150	Peroxidase.
173825	ascorbate_peroxidase	4.23e-18	102	349	10	249	Ascorbate peroxidases and cytochrome C peroxidases. Ascorbate peroxidases are a subgroup of heme-dependent peroxidases of the plant superfamily that share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Along with related catalase-peroxidases, ascorbate peroxidases belong to class I of the plant superfamily. Ascorbate peroxidases are found in the chloroplasts and/or cytosol of algae and plants, where they have been shown to control the concentration of lethal hydrogen peroxide molecules. The yeast cytochrome c peroxidase is a divergent member of the family; it forms a complex with cytochrome c to catalyze the reduction of hydrogen peroxide to water.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AUS45858.1|AA2	2.92e-140	100	363	39	300
QDS74803.1|AA2	4.08e-94	96	362	35	290
QRD03396.1|AA2	1.42e-91	97	362	33	294
QDS68272.1|AA2	1.94e-65	98	362	149	403
CAE7176693.1|AA2	3.86e-65	104	362	80	340

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5ABQ_A	1.86e-37	111	362	23	282	CRYSTAL STRUCTURE ANALYSIS OF FUNGAL VERSATILE PEROXIDASE FROM PLEUROTUS ERYNGII. MUTANT VPi-SS. MUTATED RESIDUES T2K, A49C, A61C, D69S, T70D, S86E, A131K, D146T, Q202L, Q219K, H232E, Q239R, L288R, S301K, A308R,A309K AND A314R. [Pleurotus eryngii]
5ABO_A	1.95e-35	111	362	23	282	CRYSTAL STRUCTURE ANALYSIS OF FUNGAL VERSATILE PEROXIDASE FROM PLEUROTUS ERYNGII. MUTANT VPi-br. MUTATED RESIDUES T2K, D69S, T70D, S86E, A131K, D146T, Q202L, Q219K, H232E, Q239R, L288R, S301K, A308R, A309K AND A314R. [Pleurotus eryngii]
5FNB_A	2.72e-35	111	362	23	282	Crystal Structure Of Fungal Versatile Peroxidase From Pleurotus Eryngii Septuple Mutant E37k, H39r, V160a, T184m, Q202l, D213a & G330r [Pleurotus eryngii],5FNB_B Crystal Structure Of Fungal Versatile Peroxidase From Pleurotus Eryngii Septuple Mutant E37k, H39r, V160a, T184m, Q202l, D213a & G330r [Pleurotus eryngii]
5ABN_A	1.42e-34	111	362	23	282	CRYSTAL STRUCTURE ANALYSIS OF FUNGAL VERSATILE PEROXIDASE FROM PLEUROTUS ERYNGII. MUTANT VPi. MUTATED RESIDUES D69S, T70D, S86E, D146T, Q202L, H232E, Q239R AND S301K. [Pleurotus eryngii]
2VKA_A	1.48e-34	111	362	23	282	Site-Directed Mutagenesis of the Catalytic Tryptophan Environment in Pleurotus eryngii Versatile Peroxidase [Pleurotus eryngii]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q9UR19|VPL1_PLEER	9.47e-33	111	362	53	312	Versatile peroxidase VPL1 OS=Pleurotus eryngii OX=5323 GN=vpl1 PE=1 SV=1
sp|O94753|VPL2_PLEER	1.32e-32	111	362	53	312	Versatile peroxidase VPL2 OS=Pleurotus eryngii OX=5323 GN=vpl2 PE=1 SV=1
sp|P11542|LIG4_PHACH	1.14e-31	104	362	45	318	Ligninase H2 OS=Phanerodontia chrysosporium OX=2822231 GN=GLG4 PE=1 SV=2
sp|P20013|LIGC_TRAVE	1.58e-31	107	359	46	315	Ligninase C OS=Trametes versicolor OX=5325 PE=1 SV=2
sp|C0IW58|LNP_TAICA	5.18e-30	148	359	68	286	Low-redox potential peroxidase OS=Taiwanofungus camphoratus OX=2696576 GN=LnP PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.998713	0.001284

TMHMM  Annotations     

There is no transmembrane helices in EJT79714.1.