CAZyme Information: EGD91780.1

Basic Information

• Species: Trichophyton rubrum
• Lineage: Ascomycota; Eurotiomycetes; ; Arthrodermataceae; Trichophyton; Trichophyton rubrum
• CAZyme ID: EGD91780.1
• CAZy Family: GT90
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
474		52233.96	5.6108

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_TrubrumCBS118892	8713	559305	97	8616

• Gene Location: location=GG700658:645440-646864(-)

Full Sequence      

MPLILDSTSPNPDIQSSVMAKDYKPLLPAIVVLNRRYLITGNSAAAKVGAAAFAASVVQA
FVEKGIFLGMILYQRDEDIVDPYISSEAFSSISTVTVSFNFHMDPSKVANALLSCIRILK
ATNPMEGTPMLYYQTDTLMEYHPRHIPSCVTHHGPFFGSFASIFSKEAAALAFGSMEKAE
HLERQQDKGIEIIKSRENAFVLQHSQLQGNFLASRGVTALRELCPPIELLTETEETKDEL
PENITEWFNFDGVVMFTAVARLDYFKNIDLLVDAAILLCARGIPLRVFVAGGEQPDSMEH
RALMDKVPPQYQHLFLLVPKVSRSALYSLFAVARHTGIFICPSRYETLGITPLEAALNGV
TTVISNSSVVEASRFYPEEFRFSPNPEDLSNLIVQLSGPRGTLANSGDLIRLHVGKSIQG
SKFRSDLLDAWSDFSVQYLSTLVNYVPAVQPPLCLETAPQEFGSGMKGQTRVVA

Enzyme Prediction     

No EC number prediction in EGD91780.1.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
395425	Glycos_transf_1	1.53e-16	259	396	8	141	Glycosyl transferases group 1. Mutations in this domain of PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
340831	GT4_PimA-like	1.14e-14	142	366	102	298	phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
223515	RfaB	1.92e-14	142	396	106	339	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
340816	Glycosyltransferase_GTB-type	1.14e-12	259	370	116	222	glycosyltransferase family 1 and related proteins with GTB topology. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
340830	GT4_sucrose_synthase	6.82e-12	258	366	225	333	sucrose-phosphate synthase and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UDD62545.1|GT0	3.03e-124	56	437	2	379
QRD94581.1|GT4	3.03e-124	56	437	2	379
QMW33721.1|GT4	3.03e-124	56	437	2	379
QMW45767.1|GT4	3.03e-124	56	437	2	379
APA07210.1|GT4	1.33e-106	26	444	1	419

PDB Hits     

EGD91780.1 has no PDB hit.

Swiss-Prot Hits     

EGD91780.1 has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000064	0.000000

TMHMM  Annotations     

There is no transmembrane helices in EGD91780.1.