CAZyme Information: EEU40621.1

Basic Information

• Species: Fusarium vanettenii
• Lineage: Ascomycota; Sordariomycetes; ; Nectriaceae; Fusarium; Fusarium vanettenii
• CAZyme ID: EEU40621.1
• CAZy Family: GH3
• CAZyme Description: glycosyltransferase family 20

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
910	GG698910|CGC14	103562.08	6.6717

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_Fvanettenii77134	15708	660122	0	15708

• Gene Location: location=GG698910:383971-386843(-)

Full Sequence      

MTVFVCSLFLPKTIHFTLPGTPPGADPSRRSKPAKSSNAASSSSSRPQTLARQPSLFQTQ
DDLTPPHTPTEDPESPNLFANEDGFRIQFPHAVNSPEGQDSRTWGSRSNQPKSRANSPPP
AALAEHSRTIQKARELGRQGVLQPRSLVRSDSHDRVFASANWMVVNADQGNGGLRNAAEA
AYRDGKLDDYTWVGTLGMPTDALEGTQQRQDIEDTLANEHDMLTVFCSDKDFDGHYAHFC
KHILWPVFHYQIPDNPKSKAYEDHSWKYYVNVNQAFADRIVKNWKRGDVIWIHDYHLLLV
PGMIRQKLPDAKIGFFLHVAFPSSEVFRCLAVRKELLEGMLGANLIGFQIHEYGRHFLQT
CSRLLSAEATPDGLQLEDRFVDVIHLAIGIDPISLRQHLDDQEVAKWLQIMQERYKGKKL
IVARDKLDHVRGVRQKLLSYELFLNKNPQWRENTVLIQVALSSSEKSDLEATVSDIVTRV
NSSWANLAYQPVVYLKQDIDYAQYLALLTIADALMITSQREGMNLTSHEYLFCQDGKLFP
EKKHGSLILSEFTGTSSLFNKNELAVNPWDYRQCADAIKQALEMEEPEKERRWNNLYDRV
VNHTGSHWFSEFLTRLDVVYEEQHKRDQTSVPRLSIQSLSTKYLKAQRRLFIIDYEGTLV
SWGPVNQIIPVSPQRTLDVLNDLLLDERNTIYVMSGRRPEELDRVFRRVPNLGLIAENGC
FLKSHGKDKWTEMVDLEHIKDWKESVRPIMTYYLERTPGAEIEERRCSLIFHYKSAEDYE
TASRQASDCASHVNDACESQRVHAIALDGCIAVEPIDWTKRTAARKVFETLKGEMSSNEV
HKTPVDFLMVVGDGREDEKVFKWANRLQDDKAVQNVITVSLGNRNTEATATLTQGVSGVL
TCLQRLAALA

Enzyme Prediction     

EC	2.4.1.15:11

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT20	161	617	4.3e-158	0.9305263157894736

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
340820	GT20_TPS	0.0	164	616	20	462	trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.
395781	Glyco_transf_20	0.0	144	616	1	468	Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex,.
184712	PRK14501	1.22e-171	144	908	11	725	putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional
223457	OtsA	6.09e-164	170	629	42	486	Trehalose-6-phosphate synthase [Carbohydrate transport and metabolism].
215555	PLN03063	2.56e-131	189	861	52	717	alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UPK91470.1|GT20	0.0	1	910	1	911
QKD52322.1|GT20	0.0	1	909	1	921
QGI90901.1|GT20	0.0	1	909	1	921
QGI77193.1|GT20	0.0	1	909	1	921
QGI59991.1|GT20	0.0	1	909	1	921

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6JBI_A	7.23e-101	144	617	10	463	Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBI_B Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBR_A Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_B Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_D Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_F Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_H Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_K Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_M Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_O Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBW_A Structure of Tps1/UDP complex [Pyricularia oryzae 70-15],6JBW_B Structure of Tps1/UDP complex [Pyricularia oryzae 70-15]
5HVM_A	4.81e-98	171	617	39	475	Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVM_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]
5HUT_A	3.31e-97	171	627	31	478	Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUT_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose [Candida albicans SC5314],5HUU_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HUU_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate [Candida albicans SC5314],5HVL_A Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314],5HVL_B Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A [Candida albicans SC5314]
5HUV_A	4.63e-97	171	627	31	478	Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314],5HUV_B Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose [Candida albicans SC5314]
5DXF_A	8.56e-97	234	613	146	520	Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain [Candida albicans SC5314],5DXF_B Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain [Candida albicans SC5314]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|O14081|TPSX_SCHPO	3.34e-205	65	905	97	940	Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunit OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC2E11.16c PE=1 SV=1
sp|Q9UUI7|TPSY_SCHPO	4.01e-198	110	908	114	891	Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 100 kDa subunit OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC22F8.05 PE=1 SV=1
sp|P38427|TSL1_YEAST	1.60e-166	142	816	328	976	Trehalose synthase complex regulatory subunit TSL1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TSL1 PE=1 SV=1
sp|P38426|TPS3_YEAST	1.95e-162	156	804	308	929	Trehalose synthase complex regulatory subunit TPS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TPS3 PE=1 SV=3
sp|Q54K57|TPSA_DICDI	4.15e-132	171	795	43	645	Alpha,alpha-trehalose-phosphate synthase [UDP-forming] A OS=Dictyostelium discoideum OX=44689 GN=tpsA PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000064	0.000001

TMHMM  Annotations     

There is no transmembrane helices in EEU40621.1.