CAZyme Information: EDK41340.2

Basic Information

• Species: Meyerozyma guilliermondii
• Lineage: Ascomycota; Saccharomycetes; ; Debaryomycetaceae; Meyerozyma; Meyerozyma guilliermondii
• CAZyme ID: EDK41340.2
• CAZy Family: GT71
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
856		98258.19	6.3888

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_MguilliermondiiATCC6260	6062	294746	142	5920

• Gene Location: location=CH408161:480125-482695(+)

Full Sequence      

MGLFGKSSLPGHPAVEQTIGSWHFRQCGEASWRNASTSTNGNQVHLDLLENGDISDPFID
MNEKSVQWVGENDWEYQTTFDVSDAASACLTHEMHFDGLDTFCAAALNGTEILRSDNMFR
GYVVDVTKHIKEKDNELVLVFKSALKKGRELEKKNGVRFCSNGETSRVHVRKAQYHYGWD
WGPLLMTCGPWKPVRLVSFSAGKFLDFFPRCSVDSDLKATINFEVEVEVSGTSTVFVDIF
APTGEIIDTVEQKIKKSGVANFKYKLKNPKLWYPKGYGEQSRYRFSARLVDGNNFLLDTK
DKLIGLRRAELVQEKVADEKGLSFYFRINNIPVYCAGSNWIPAHSFTCKLTEKDYKEWMQ
LVDEGNQNMVRVWGGGIYEYDWLYEECDKRGILVWQDFMFGCAVYPGDKEFVQNVKEEVE
YQVKRLRQFCSIVIYAGNNEDYQVAESLGIRWDSNDSKKNYSKTEFPARTLYEVVFPKLV
SSLTDVAYHKGSPYSPGHNIPTSDQTVGDLHQWNVWHGSQEKYQDWYKLGGRFVSEFGML
AFPNVKTIDKYVTTDKDKYPQSEVMDHHNKSDGFERRLALYVMENFHVQDMRLKNWVYIT
QLMQSECLAYAYRCWRRNWGRDGKRASGGALVWQTNDCWPVTSWAIIDFFRVPKLAYYAV
KRESQPLALGIYRNEVRIANEGEPDLSKQTPYHDYAAREYYVDIWGVNSSLFEFQGVLRV
EIYDSESGNLVKKLNDKNVLLAANQTTEIISRLHLPDFKQVVLAKLVGQDGNIAFKAGDW
PQPLKYIRWPEDTKIDVLVAEDGIVKITANKLVKGVELITDSKLNDNGFDLYPNETHVVL
APGIKAGEKIEINYLK

Enzyme Prediction     

EC	3.2.1.25:3

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	20	681	1.9e-83	0.6276595744680851

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
225789	LacZ	1.54e-70	6	669	2	634	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
407658	Mannosidase_ig	1.90e-10	702	786	3	91	Mannosidase Ig/CBM-like domain. This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.
395572	Glyco_hydro_2	4.81e-10	206	307	5	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
407625	Ig_mannosidase	5.88e-04	792	839	1	54	Ig-fold domain. This Ig-like fold domain is found in mannosidase enzymes.
236657	PRK10150	0.002	213	337	193	296	beta-D-glucuronidase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CAG87955.2|GH2	0.0	18	856	11	843
ANB14378.1|GH2	2.78e-308	7	854	2	858
SGZ52529.1|GH2	2.01e-302	18	854	6	832
QPG76551.1|GH2	2.94e-301	22	854	14	850
SGZ48501.1|GH2	3.26e-301	18	854	6	832

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5N6U_A	9.46e-145	2	839	13	808	Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_B Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_C Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_D Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12]
2VJX_A	1.78e-116	22	853	15	830	Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A	1.87e-116	22	853	17	832	Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
7OP6_A	1.91e-116	22	853	17	832	Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A	4.99e-116	22	853	15	830	Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|I2C092|MANBB_THETO	1.03e-227	21	855	12	852	Beta-mannosidase B OS=Thermothelomyces thermophilus OX=78579 GN=man9 PE=1 SV=1
sp|Q5B7W2|MANBB_EMENI	2.13e-206	22	848	13	833	Beta-mannosidase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=mndB PE=1 SV=2
sp|Q2TXB7|MANBB_ASPOR	1.95e-201	44	848	36	834	Beta-mannosidase B OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=mndB PE=3 SV=3
sp|B8NW36|MANBB_ASPFN	1.55e-200	44	848	36	834	Beta-mannosidase B OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) OX=332952 GN=mndB PE=3 SV=1
sp|Q4WAH4|MANBB_ASPFU	5.02e-199	44	848	36	835	Beta-mannosidase B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=mndB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999902	0.000139

TMHMM  Annotations     

There is no transmembrane helices in EDK41340.2.