CAZyme Information: EAW22977.1

Basic Information

• Species: Aspergillus fischeri
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus fischeri
• CAZyme ID: EAW22977.1
• CAZy Family: GH76
• CAZyme Description: conserved hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
651		74670.59	6.3002

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AfischeriNRRL181	10668	331117	278	10390

• Gene Location: location=DS027688:2663359-2665725(-)

Full Sequence      

MEYPQESFKATTFAPDSFWAQRRQVVRSQTLRHQLQMMKDTGRYDAFKLKWHPSYSDPCT
VWPVPNHLFWDSDVAKWIEGACYFLMDYPDEEIDAAIRELVEMIQNAQQSDGYLNIHYTV
VEPGKRFTNLRDMHELYNAGHLVEAALAHRLLYRNDELLSPILKYVALLAATFGNKEGQK
AGYPGHPEIELALLRLYKVTQDPEHLRLARFFLEERGNPSGGKERRHYYDVEAEARGERK
HEVPEAYPAARSYWYQQAHVPITQQQTIEGHAVRAMYLLTSVTDLVRICEPSSDVANKFL
PALHRLWSNMIEKKSYMTGGIGAMKQWEGFGIDYFLPHGTDEGGCYAETCAAIGVMMLAE
RLLQVELHSHYADILELCLYNAVLTGMSLDGKGFTYVNQLASSEKDLSRRYEWFECACCP
PNVTRTLGCLGGYLWSYKVNNERQKATVNVHLYTSATLRFQVADSRIEITQKTQWPWNGD
VSFSVNIDGPPVNLELRLRIPGWASTWEPSWPDLHDGYLYLPSDWIQQHAEFSLSCPMRP
RVVRPHPLTMQPVAYVTRGPIVYCVEDVDNSWENDHFKEEVQSTPDHHVGIIAQGGSRGT
LDTTRWKRQIVAESGDVAPISEDVRDLCFIPYYLRANRGGKGQMRVGLRVE

Enzyme Prediction     

EC	3.2.1.185:2

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH127	16	564	4.8e-167	0.9904580152671756

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
226063	COG3533	1.35e-132	18	651	22	588	Uncharacterized conserved protein, DUF1680 family [Function unknown].
400342	Glyco_hydro_127	1.48e-116	16	564	6	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QYT01986.1|GH127	1.42e-282	1	649	1	660
ATZ54433.1|GH127	1.07e-275	1	649	1	660
CCD50963.1|GH127	4.51e-273	1	645	1	656
QKX55142.1|GH127	2.85e-263	1	651	1	674
UJO16417.1|GH127	6.18e-262	1	649	1	679

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4QJY_A	8.93e-120	16	646	20	643	Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QJY_B Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
4QK0_A	2.52e-115	16	639	20	637	Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_B Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_C Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_D Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
6EX6_A	9.18e-98	4	651	11	626	The GH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482],6EX6_B The GH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482]
3WRE_A	1.83e-89	68	646	72	654	The crystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 [Bifidobacterium longum subsp. longum JCM 1217],3WRG_A The complex structure of HypBA1 with L-arabinose [Bifidobacterium longum subsp. longum JCM 1217]
3WKW_A	2.37e-89	68	646	72	654	Crystal structure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum ligand free form [Bifidobacterium longum subsp. longum JCM 1217],3WKX_A Crystal structure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum arabinose complex form [Bifidobacterium longum subsp. longum JCM 1217],7BZL_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7DIF_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXV_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXW_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|E8MGH8|HYBA1_BIFL2	9.43e-89	68	646	72	654	Non-reducing end beta-L-arabinofuranosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=hypBA1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000075	0.000000

TMHMM  Annotations     

There is no transmembrane helices in EAW22977.1.