CAZyme Information: EAQ84111.1

Basic Information

• Species: Chaetomium globosum
• Lineage: Ascomycota; Sordariomycetes; ; Chaetomiaceae; Chaetomium; Chaetomium globosum
• CAZyme ID: EAQ84111.1
• CAZy Family: AA7
• CAZyme Description: Lysozyme [Source:UniProtKB/TrEMBL;Acc:Q2GND9]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
258		27216.24	9.9628

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CglobosumCBS148.51	11232	306901	184	11048

• Gene Location: location=CH408035:2969024-2969950(-)

Full Sequence      

MKFLVFATLAASAIAYPITGSVVNCRSGPGTSYAVKKSYNKGADVTISCQTTGTSVNGNS
IWDKTQDGCYVADYYVKTGTNGYVTKKCGGTSTCAAPKSNSATVDLIAKSEGFRANVYND
PAGHPTVGYGHLCTKAKCAEIKYKIPLSTTDGKKLLADDMKKFEKCITAMLNSKAKLNLN
QYGALVSWSFNVGCGAAQGSQLVKRLNKGENVNTVLSNELPKWVNAGGKKLPGLVTRRNN
EIALAKKSGSGAALPVKC

Enzyme Prediction     

No EC number prediction in EAQ84111.1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH24	101	241	2.3e-38	0.9781021897810219

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
381599	lyz_endolysin_autolysin	1.97e-53	104	244	2	134	endolysin and autolysin. The dsDNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell walls. Similarly, bacteria produce autolysins to facilitate the biosynthesis of its cell wall heteropolymer peptidoglycan and cell division. Endolysins and autolysins are found in viruses and bacteria, respectively. Both endolysin and autolysin enzymes cleave the glycosidic beta 1,4-bonds between the N-acetylmuramic acid and the N-acetylglucosamine of the peptidoglycan.
381620	lyz_P1	1.84e-37	102	244	5	138	P1 lysozyme Lyz-like proteins. Enterobacteria phage P1 lysozyme Lyz is secreted to the Escherichia coli periplasm where it is membrane bound and inactive. Activation involves the release from the membrane, an intramolecular thiol-disulfide isomerization and extensive structural rearrangement of the N-terminal region. The dsDNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell walls. Similarly, bacteria produce autolysins to facilitate the biosynthesis of its cell wall heteropolymer peptidoglycan and cell division. Endolysins and autolysins are found in viruses and bacteria, respectively. Both endolysin and autolysin enzymes cleave the glycosidic beta 1,4-bonds between the N-acetylmuramic acid and the N-acetylglucosamine of the peptidoglycan.
381619	endolysin_R21-like	1.00e-27	101	244	6	140	endolysin R21-like proteins. Unlike T4 E phage lysozyme, the endolysin R21 from Enterobacteria phage P21 has an N-terminal SAR (signal-arrest-release) domain that anchors the endolysin to the membrane in an inactive form, which act to prevent premature lysis of the infected bacterium. The dsDNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell walls. Similarly, bacteria produce autolysins to facilitate the biosynthesis of its cell wall heteropolymer peptidoglycan and cell division. Endolysins and autolysins are found in viruses and bacteria, respectively. Both endolysin and autolysin enzymes cleave the glycosidic beta 1,4-bonds between the N-acetylmuramic acid and the N-acetylglucosamine of the peptidoglycan.
226295	RrrD	1.70e-25	101	244	9	146	Phage-related lysozyme (muramidase), GH24 family [Cell wall/membrane/envelope biogenesis].
395766	Phage_lysozyme	5.21e-12	124	238	1	106	Phage lysozyme. This family includes lambda phage lysozyme and E. coli endolysin.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AEO62022.1|GH24	2.70e-143	1	258	1	266
AEO71812.1|GH24	3.95e-137	1	258	1	261
QKD50435.1|GH24	1.01e-127	1	258	1	259
QGI87874.1|GH24	3.69e-111	10	258	13	258
QGJ01409.1|GH24	3.69e-111	10	258	13	258

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6ET6_A	1.77e-17	104	247	57	195	Chain A, Lysozyme [Acinetobacter baumannii]
7M5I_A	4.00e-12	104	241	14	149	Chain A, Endolysin [Escherichia coli O157 typing phage 15],7M5I_B Chain B, Endolysin [Escherichia coli O157 typing phage 15]
2ANV_A	5.18e-10	100	244	5	143	Chain A, Lysozyme [Lederbergvirus P22],2ANV_B Chain B, Lysozyme [Lederbergvirus P22],2ANX_A Chain A, Lysozyme [Lederbergvirus P22],2ANX_B Chain B, Lysozyme [Lederbergvirus P22]
6H9D_A	1.80e-08	95	244	2	145	Chain A, Lysozyme [Asticcacaulis excentricus],6H9D_B Chain B, Lysozyme [Asticcacaulis excentricus],6H9D_C Chain C, Lysozyme [Asticcacaulis excentricus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P11187|ENLYS_BPPH2	4.85e-15	100	244	4	141	Endolysin OS=Bacillus phage phi29 OX=10756 GN=15 PE=1 SV=1
sp|P07540|ENLYS_BPPZA	9.20e-15	100	244	4	141	Endolysin OS=Bacillus phage PZA OX=10757 GN=15 PE=3 SV=1
sp|Q37896|ENLYS_BPB03	3.51e-14	100	244	4	141	Endolysin OS=Bacillus phage B103 OX=10778 GN=15 PE=3 SV=1
sp|Q9T1T5|ENLYS_BPAPS	8.08e-12	106	244	10	142	Endolysin OS=Acyrthosiphon pisum secondary endosymbiont phage 1 OX=2682836 GN=13 PE=3 SV=1
sp|P09963|ENLYS_BPP22	1.41e-09	100	244	5	143	Endolysin OS=Salmonella phage P22 OX=10754 GN=19 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000283	0.999684	CS pos: 15-16. Pr: 0.9653

TMHMM  Annotations     

There is no transmembrane helices in EAQ84111.1.