CAZyme Information: CXQ85_003448-t46_1-p1

Basic Information

• Species: [Candida] haemuloni
• Lineage: Ascomycota; Saccharomycetes; ; Debaryomycetaceae; Candida; [Candida] haemuloni
• CAZyme ID: CXQ85_003448-t46_1-p1
• CAZy Family: GT32
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1505		167325.06	6.4223

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_ChaemulonisB11899	5409	N/A	160	5249

• Gene Location: location=PKFO01000002:606737-611883(-)

Full Sequence      

MPPKKSAASRANGSSKVPNLPGIKHNAPRSTRNFFPSDSDESPPEDTPEKKRAQPSKKTR
SILGGTNSLKAMFSNSQEAQKEKEPESSQESTPVKKPAKRGRKPKQTVASPEAPIHEAST
PKSMLKRATKSLESPSASKPIRFDDIEEEPPKRSKSSRSKEQQSEPLPKKRRKKNQPRED
DDYVEQHSQHTIQLADGDRPGPIRRSSYSNRGKRTSSIGNGFVAKPHDEMSVTEYYKVID
SSLPGPSRMRQVLVWCFKKKLQQDRESEGAETNTAKGIAKVIKNEILEDLVSKKIDTSWL
SAKRFDASELQGKRVIKSNPLNDANQESYEVFKQKLRELRQEKSHWQSAFDASVKPLEGL
AISSEDEEGKYSREFKEYVKQKDPKLGAVLQEEHLETLSQQVKQVEASVPEKLEANMAQL
FHTAYQLSKSVELVGKIRQESLAPQVTQVVKEFMERNRHSKQGKHQVNGDDGTRLGHLQN
LVVSQENKAIFTKLLYADNAYYDKDTHTLGTLDWVPQHQYQRQPYVANGYLGSRIPNLGQ
GFAYDTLANGTYVDVSTPDADLPSDLSNGWPLFNRRYAGAFVAGFYNLQENTTSNNFPWL
LEDGYESVVAAVPQWTSLALTAKKGSKSYTLDPAGNPDSYGKITNYAQNLSLADGIVTTT
FTWLGSLDVKYTVLAHRSKLSLGLVSLHVENTADSNITVSVQDSLDFGTAQRARFDSTSV
DKENRALYMLYSPNDIDYVYGATYSSLRYDTSESHCLGSEFTTSHFSSGHTVTFDIPAKS
SIDVTKHVGVVTSDLDPKKYTSFDLVLSEAKATSLAKDSFESLSTSHREEWGNSMDAGLT
VEFPDDPLLSLAARASIYHLNANTRPDAEGVTAALGVSGLSSDSYGGMVFWDTDLWMMNG
LLPFNPSHARSIVNYRLHTHDQARKNVDSDRTPKKDMHGAAFPWTSGRFGNCTATGPCFD
YEYHINMAVAISAWELYKSGAADDHFLEHSAFPLINDAAALFADYVEYNDTLQAYSTHNL
TDPDEYANHVDNGAYTNSAISATMRWAIAVSEHLGKPVPKSYQNIMGNMHLPRSADDSDI
ILEFTGMNSSIEIKQADVVMLTYPLENELITLDSAKASMEYASMKQVSFGPAMTFPIFSI
VSSALSEKGCSADTYLMKSIQPFLRGPFAQFSEQNSDDYLTNGGTHPAFPFMTAHGGFLQ
AILQGILGLRFDHKVEDGKIVRFLKLDPIKLKTLPSGVYFDGVHYMNQTLAFNLTSEGLA
VKHNGPIKGSVPHKILIELGSRNPDAGTHTLMPGTDATFKLYETEDTFKNSLSECGRALF
TNITECAPGDAPVLANDGDNTTHWQAKTPEKSKVLIDFLEPIVLQTCSINWGDKPPKSVK
LSATAQDLSSEYPDLLETVDFLSNVDFGTDLPRKYSYNNPGGKLYKQSDIFTAVDSREVS
INEPFRLEEQHLIVLPSRHNTTDINLDSPIKTRYALLEFEGVHDKRSKDDKESQKGAKIY
ELNFF

Enzyme Prediction     

EC	3.2.1.28:7

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH65	854	1213	4.8e-88	0.9946236559139785

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
224471	ATH1	9.60e-82	526	1254	32	733	Trehalose and maltose hydrolase (possible phosphorylase) [Carbohydrate transport and metabolism].
369747	MIS13	1.84e-41	186	460	4	271	Mis12-Mtw1 protein family. Mis12-Mtw1 is a eukaryotic conserved kinetochore protein that is involved in chromosome segregation.
281612	Glyco_hydro_65m	9.90e-38	854	1212	1	383	Glycosyl hydrolase family 65 central catalytic domain. This family of glycosyl hydrolases contains vacuolar acid trehalase and maltose phosphorylase.Maltose phosphorylase (MP) is a dimeric enzyme that catalyzes the conversion of maltose and inorganic phosphate into beta-D-glucose-1-phosphate and glucose. The central domain is the catalytic domain, which binds a phosphate ion that is proximal the the highly conserved Glu. The arrangement of the phosphate and the glutamate is thought to cause nucleophilic attack on the anomeric carbon atom. The catalytic domain also forms the majority of the dimerization interface.
397616	Glyco_hydro_65N	3.08e-22	517	793	10	240	Glycosyl hydrolase family 65, N-terminal domain. This family of glycosyl hydrolases contains vacuolar acid trehalase and maltose phosphorylase.Maltose phosphorylase (MP) is a dimeric enzyme that catalyzes the conversion of maltose and inorganic phosphate into beta-D-glucose-1-phosphate and glucose. This domain is believed to be essential for catalytic activity although its precise function remains unknown.
237517	PRK13807	1.46e-14	642	1083	105	552	maltose phosphorylase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QWU86795.1|GH65	0.0	471	1505	34	1068
QRG36869.1|GH65	0.0	461	1505	32	1082
QEO21230.1|GH65	0.0	461	1505	32	1082
QWW21864.1|GH65	0.0	461	1505	51	1101
QEL58660.1|GH65	0.0	461	1505	32	1082

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7FE3_A	1.50e-40	643	1212	100	643	Chain A, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE3_B Chain B, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE3_C Chain C, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE4_A Chain A, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE4_B Chain B, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101],7FE4_C Chain C, Candidate alpha glycoside phosphorylase Glycoside hydrolase family 65 [Flavobacterium johnsoniae UW101]
3WIQ_A	1.50e-24	819	1275	274	749	Crystal structure of kojibiose phosphorylase complexed with kojibiose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_A Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_B Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_C Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903],3WIR_D Crystal structure of kojibiose phosphorylase complexed with glucose [Caldicellulosiruptor saccharolyticus DSM 8903]
4KTP_A	3.71e-17	768	1086	221	549	Chain A, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTP_B Chain B, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10]
4KTR_A	4.88e-17	768	1086	221	549	Chain A, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_B Chain B, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_C Chain C, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_D Chain D, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_E Chain E, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_F Chain F, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_G Chain G, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10],4KTR_H Chain H, Glycoside hydrolase family 65 central catalytic [[Bacillus] selenitireducens MLS10]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q5AAU5|ATC1_CANAL	0.0	477	1505	78	1078	Cell wall acid trehalase ATC1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=ATC1 PE=1 SV=2
sp|M1RNJ8|ATH1_CANGB	2.55e-219	485	1502	145	1208	Periplasmic/secreted acid trehalase ATH1 OS=Candida glabrata OX=5478 GN=ATH1 PE=1 SV=1
sp|N1P212|ATH1_YEASC	2.44e-208	463	1502	97	1207	Periplasmic acid trehalase ATC1 OS=Saccharomyces cerevisiae (strain CEN.PK113-7D) OX=889517 GN=CENPK1137D_1727 PE=1 SV=1
sp|P48016|ATH1_YEAST	2.44e-208	463	1502	97	1207	Periplasmic acid trehalase ATH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=ATH1 PE=1 SV=1
sp|D4B5H9|ATC1_ARTBC	4.18e-117	517	1481	76	1026	Cell wall acid trehalase ARB_03719 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=ARB_03719 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000050	0.000000

TMHMM  Annotations     

There is no transmembrane helices in CXQ85_003448-t46_1-p1.