dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: CTRG_05100-t43_1-p1

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Basic Information help

Species

Candida tropicalis

Lineage

Ascomycota; Saccharomycetes; ; Debaryomycetaceae; Candida; Candida tropicalis

CAZyme ID

CTRG_05100-t43_1-p1

CAZy Family

GT48

CAZyme Description

chitin synthase 1

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1037	GG692401\|CGC5	117718.86	6.3249

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CtropicalisMYA3404	6441	294747	187	6254

Gene Location

Full Sequence Download help

Enzyme Prediction help

EC	2.4.1.16:26	2.4.1.16:26

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GT2	349	511	4.7e-75	0.9938650306748467

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396286	Chitin_synth_1	5.51e-105	349	511	1	163	Chitin synthase. This region is found commonly in chitin synthases classes I, II and III. Chitin a linear homopolymer of GlcNAc residues, it is an important component of the cell wall of fungi and is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases.
133033	Chitin_synth_C	1.26e-92	345	673	1	244	C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin. Chitin synthase, also called UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase, catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of GlcNAc residues formed by covalent beta-1,4 linkages. Chitin is an important component of the cell wall of fungi and bacteria and it is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. Studies with fungi have revealed that most of them contain more than one chitin synthase gene. At least five subclasses of chitin synthases have been identified.
400626	Chitin_synth_1N	2.04e-30	275	348	1	70	Chitin synthase N-terminal. This is the N-terminal domain of Chitin synthase (pfam01644).
224136	BcsA	4.43e-28	343	800	56	402	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
367353	Chitin_synth_2	5.64e-19	490	872	205	490	Chitin synthase. Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They catalyze chitin synthesis as follows: UDP-N-acetyl-D-glucosamine + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N) <=> UDP + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N+1).

CAZyme Hits help

E-Value	Query Start	Query End	Hit Start
1	1034	1	1026
1	1034	1	1026
1	1034	1	1026
1	1034	1	1027
1	1034	1	1027

PDB Hits help

CTRG_05100-t43_1-p1 has no PDB hit.

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
0.0	256	1034	1	776	Chitin synthase 1 OS=Candida albicans OX=5476 GN=CHS1 PE=2 SV=2
1.36e-277	282	1017	233	941	Chitin synthase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CHS2 PE=1 SV=1
8.79e-260	267	1018	236	975	Chitin synthase 2 OS=Paracoccidioides brasiliensis OX=121759 GN=CHS2 PE=3 SV=2
1.35e-259	267	1018	219	958	Chitin synthase A OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=chsA PE=3 SV=2
1.06e-257	267	1025	319	1068	Chitin synthase 2 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=chs-2 PE=3 SV=4

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000039	0.000002

TMHMM Annotations download full data without filtering help

Start	End
666	685
705	727
742	764
776	798
813	835
951	970
980	1002