CAZyme Information: CPC735_058530-t26_1-p1

Basic Information

• Species: Coccidioides posadasii
• Lineage: Ascomycota; Eurotiomycetes; ; Onygenaceae; Coccidioides; Coccidioides posadasii
• CAZyme ID: CPC735_058530-t26_1-p1
• CAZy Family: GT24
• CAZyme Description: glyoxal oxidase, putative

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
615	ACFW01000049|CGC16	67555.43	6.1532

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CposadasiiC735deltSOWgp	7255	222929	26	7229

• Gene Location: location=ACFW01000049:4529145-4531096(+)

Full Sequence      

MSQSNEQPVDEPLLRPAPPNTPAGDSDGSTLVTNNGHCGSAHKNTVCGDWPKGSCCSPFG
ICGNTTSHCGYGCQSGACLSEDALKPPAPIRFRPSRLPGQFHVIGRSGVPPMIAVLLQNG
RVAFADKVENYTEVVLENGRYAYSTEFDPITSSLAPLSYKTNVFCSGGTFLADGRVLSVG
GNGPLKWMDPTVDDGFRGIRYLERRFDDDNFDGTPWEEPGHQLSTGRWYPTVQTLSDGRV
FVVSGSLNGDDPSVMQNNNPTYELLDKNGFPSGNSVELSILDKNQPYYMYPFLHLLNDGT
VFIFVSRSAEVFDVDAGVTVKTLPDLPGDYRTYPNTGGSVLLPLRSANGWEPEIIICGGG
AFQDIDSPSDPTCGRIRPLSEEPRWELEAMPGGRIMSEGILLPDGTVIWINGCRNGAQGY
GIAENPIYNPWIYRPQAPPKKRWAIGGTSEVPRMYHSVALLLLDGTVLVAGSNPVEQPLL
VTNPNDPMLAFPTEFRVEIYTPHYFMDGKADRRPRKIVISSRYLEPDGNFDITFHNRRPA
RKLSIVLYHGGFVTHSVHMGHRMLYLDHQGWKSWRKKQKVSVKMPPTSSVVPPGPYVIYI
VVDGIPGEGQFVMVA

Enzyme Prediction     

No EC number prediction in CPC735_058530-t26_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA5	97	614	2.2e-147	0.9502664298401421

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
399910	Glyoxal_oxid_N	2.22e-52	112	359	1	243	Glyoxal oxidase N-terminus. This family represents the N-terminus (approximately 300 residues) of a number of plant and fungal glyoxal oxidase enzymes. Glyoxal oxidase catalyzes the oxidation of aldehydes to carboxylic acids, coupled with reduction of dioxygen to hydrogen peroxide. It is an essential component of the extracellular lignin degradation pathways of the wood-rot fungus Phanerochaete chrysosporium.
401164	DUF1929	6.07e-27	519	614	1	91	Domain of unknown function (DUF1929). Members of this family adopt a secondary structure consisting of a bundle of seven, mostly antiparallel, beta-strands surrounding a hydrophobic core. The 7 strands are arranged in 2 sheets, in a Greek-key topology. Their precise function, has not, as yet, been defined, though they are mostly found in sugar-utilising enzymes, such as galactose oxidase.
199882	E_set_GO_C	9.64e-19	508	614	1	103	C-terminal Early set domain associated with the catalytic domain of galactose oxidase. E or "early" set domains are associated with the catalytic domain of galactose oxidase at the C-terminal end. Galactose oxidase is an extracellular monomeric enzyme which catalyzes the stereospecific oxidation of a broad range of primary alcohol substrates and possesses a unique mononuclear copper site essential for catalyzing a two-electron transfer reaction during the oxidation of primary alcohols to corresponding aldehydes. The second redox active center necessary for the reaction was found to be situated at a tyrosine residue. The C-terminal domain of galactose oxidase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.
211316	ChtBD1_1	3.75e-13	38	77	2	40	Hevein or type 1 chitin binding domain; filamentous ascomycete subfamily. Hevein or type 1 chitin binding domain (ChtBD1), a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins such as hevein, a major IgE-binding allergen in natural rubber latex, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements.
395135	Chitin_bind_1	2.09e-12	38	75	2	36	Chitin recognition protein.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS69861.1|AA5|CBM18	3.69e-275	33	614	46	627
QSS64055.1|AA5|CBM18	8.08e-272	33	614	46	627
QSZ32349.1|AA5|CBM18	6.67e-246	11	614	211	812
APA08794.1|AA5|CBM18	2.24e-245	2	614	211	817
CAD89674.1|AA5_1|CBM18	9.91e-245	11	614	55	656

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4UNM_A	4.82e-18	218	614	251	614	Structure of Galactose Oxidase homologue from Streptomyces lividans [Streptomyces lividans],4UNM_B Structure of Galactose Oxidase homologue from Streptomyces lividans [Streptomyces lividans]
5LXZ_B	2.39e-16	218	614	240	603	W288A mutant of GlxA from Streptomyces lividans: Cu-bound form [Streptomyces lividans TK24]
5LQI_A	2.41e-16	218	614	245	608	W288A mutant of GlxA from Streptomyces lividans: apo form [Streptomyces lividans 1326],5LQI_B W288A mutant of GlxA from Streptomyces lividans: apo form [Streptomyces lividans 1326]
6XLT_A	4.52e-16	144	614	205	638	Chain A, Galactose oxidase [Fusarium graminearum]
2EIC_A	5.89e-16	144	614	204	637	Chain A, Galactose oxidase [Fusarium graminearum]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q3HRQ2|GLOX_VITPS	1.48e-67	97	612	13	519	Aldehyde oxidase GLOX OS=Vitis pseudoreticulata OX=231512 GN=GLOX PE=2 SV=1
sp|Q9FYG4|GLOX1_ARATH	1.40e-59	143	614	157	614	Aldehyde oxidase GLOX1 OS=Arabidopsis thaliana OX=3702 GN=GLOX1 PE=2 SV=1
sp|Q01772|GLOX_PHACH	1.59e-54	107	613	35	548	Aldehyde oxidase GLOX OS=Phanerodontia chrysosporium OX=2822231 GN=GLX PE=1 SV=1
sp|D4AUF1|WSCD1_ARTBC	3.70e-54	63	614	386	903	WSC domain-containing protein ARB_07867 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=ARB_07867 PE=1 SV=1
sp|A0A2H4HHY6|GLOX_ARTAN	4.00e-45	147	612	132	591	Putative aldehyde oxidase Art an 7 OS=Artemisia annua OX=35608 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999289	0.000764

TMHMM  Annotations     

There is no transmembrane helices in CPC735_058530-t26_1-p1.