CAZyme Information: CPAG_08138-t26_1-p1

Basic Information

• Species: Coccidioides posadasii
• Lineage: Ascomycota; Eurotiomycetes; ; Onygenaceae; Coccidioides; Coccidioides posadasii
• CAZyme ID: CPAG_08138-t26_1-p1
• CAZy Family: GT34
• CAZyme Description: NOT-56 mannosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
394		44366.87	9.4391

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CposadasiiRMSCC3488	10016	454284	119	9897

• Gene Location: location=DS268113:2349113-2350416(-)

Full Sequence      

MELCRLCIDLCTNPKHSKWICPLLLLAESVLCSLIVWKIPYTEIDWSTYMQQVSIFLSGE
RDYTLIKGSTGPLVYPAGHVYAFSLLYSVTDEGRDIAFGQIIFAGLYIVALALVMATYWS
AGAPPYIYPLLVLSKRLHSIFMLRMFNDGIATLLLWATIYMLQKRRWSTAVILWSAGVSV
KMTLLLVAPALAVILTLAVGFPSALGLGILSLLVQLLIAIPFLQKSPVGYFSRAFEFTRQ
FLFKWTVNWRFVGEEIFLSRSFSLTLLVVHLSLLALFLGFSWLHPSRKSLTQIARDILQG
KNTRYTLTTNFITKTMLTSLVIGFLCARSLHYQFFSYLAWASPLLLWESGLRPLYIFALC
LIQEYAWNVYPGTSLSSMAVVMALASQVLAPALN

Enzyme Prediction     

EC	2.4.1.258:10

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT58	22	377	2.7e-139	0.9945054945054945

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
398745	ALG3	0.0	22	377	1	358	ALG3 protein. The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl pyrophosphate. Whereas early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9GlcNAc2-PP-Dol on the lumenal side use Dol-P-Man. ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QVM12997.1|GT58	2.72e-278	1	394	1	394
QSS55330.1|GT58	1.42e-174	1	389	1	389
QSS72893.1|GT58	1.64e-173	1	389	1	389
BAE62911.1|GT58	2.55e-169	1	394	1	394
UDD58266.1|GT58	2.55e-169	1	394	1	394

PDB Hits     

CPAG_08138-t26_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q2U6A4|ALG3_ASPOR	4.53e-170	1	394	1	394	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=alg3 PE=3 SV=1
sp|A1CBE6|ALG3_ASPCL	1.16e-162	1	389	63	451	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=alg3 PE=3 SV=1
sp|Q4WVG2|ALG3_ASPFU	7.17e-161	1	388	9	396	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=alg3 PE=3 SV=1
sp|A1DDZ3|ALG3_NEOFI	2.42e-152	1	388	1	388	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=alg3 PE=3 SV=1
sp|A2RA94|ALG3_ASPNC	7.99e-148	1	387	1	383	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=alg3 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000010	0.000008

TMHMM  Annotations     

Start	End
19	41
97	119
140	162
172	194
201	223
262	284
305	327
337	359
366	388