CAZyme Information: CND05940-t26_1-p1

Basic Information

• Species: Cryptococcus neoformans
• Lineage: Arthropoda; Insecta; ; Eriococcidae; Cryptococcus; Cryptococcus neoformans
• CAZyme ID: CND05940-t26_1-p1
• CAZy Family: GH13
• CAZyme Description: capsular associated protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
641	AE017344.1|CGC8	74394.14	6.6005

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CneoformansJEC21	7004	214684	372	6632

• Gene Location: location=AE017344.1:1632876-1635128(+)

Full Sequence      

MPLRFRVSLLTFTVALVVLLTYSYFYLSSHSEDDSYFEIVDGPGSRHPSSPLDKSHSPHR
DLVQWWSPLASEGPLGVLKFSGDGLVRGWDGVYNKLKSGGLKRSERKKLQLAMERHPILE
LMERNHERWENLLASQSKTLPQAVTEYTRRYGRPPPKGFDQWWQFCKRNKVKIVDDYDQI
NRDIELYFALSPELFRKRVDLLKETPHTSQITLSPIRQSSLYGERAHSLRARLLFQLIEP
IAQFLPGDITFSLSDHDLGSWLLGDDQKQAALDAIRNGRYLTEEELEVYEKREGRQAVKG
LASACPPGSPGWQHGVARRDGLEIKELPKETTFIYDPGLTYDYCYTPELVDIHGALSWDS
ARESMLRPIFQLSKFARNPEFLTTPLEAYENFTSPAAQKKYAPWDEKTIDKLFWRGSSTG
DFYSKRLSSPTWRQSHRPRLALKTQATEVEEEVWVQRGKMWEKETWSVARLNKAYMDVGL
TGGPHQCKKEDGTCDEMEQEIIFKDRVAPEDSAKYKYVFDIDGNGWSSRFHRLIMSGSVV
LKATIYPEWVSEWLTPWVHYIPCKVDYSDLYDIMSFFAGPPDGHAGGHDNLAKMIADQAR
QFGEDHWRWEDMQAYMFRLLLEYSRLLADDRNEWSYQKIYT

Enzyme Prediction     

No EC number prediction in CND05940-t26_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT90	363	627	1.5e-69	0.908

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
214773	CAP10	8.23e-27	491	627	123	253	Putative lipopolysaccharide-modifying enzyme.
310354	Glyco_transf_90	5.30e-16	498	627	200	323	Glycosyl transferase family 90. This family of glycosyl transferases are specifically (mannosyl) glucuronoxylomannan/galactoxylomannan -beta 1,2-xylosyltransferases, EC:2.4.2.-.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AAW43180.1|GT90	0.0	1	641	1	641
AAN75727.2|GT90	0.0	1	641	1	641
UOH80583.1|GT90	0.0	1	641	1	641
AAN75174.2|GT90	0.0	1	641	1	641
AUB24364.1|GT90	0.0	1	641	1	641

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5L0R_A	7.96e-15	511	628	233	343	human POGLUT1 in complex with Notch1 EGF12 and UDP [Homo sapiens],5L0S_A human POGLUT1 in complex with Factor VII EGF1 and UDP [Homo sapiens],5L0T_A human POGLUT1 in complex with EGF(+) and UDP [Homo sapiens],5L0U_A human POGLUT1 in complex with EGF(+) and UDP-phosphono-glucose [Homo sapiens],5L0V_A human POGLUT1 in complex with 2F-glucose modified EGF(+) and UDP [Homo sapiens],5UB5_A human POGLUT1 in complex with human Notch1 EGF12 S458T mutant and UDP [Homo sapiens]
5F84_A	1.38e-10	505	627	262	379	Crystal structure of Drosophila Poglut1 (Rumi) complexed with its glycoprotein product (glucosylated EGF repeat) and UDP [Drosophila melanogaster],5F85_A Crystal structure of Drosophila Poglut1 (Rumi) complexed with its substrate protein (EGF repeat) and UDP [Drosophila melanogaster],5F86_A Crystal structure of Drosophila Poglut1 (Rumi) complexed with its substrate protein (EGF repeat) [Drosophila melanogaster],5F87_A Crystal structure of Drosophila Poglut1 (Rumi) complexed with UDP [Drosophila melanogaster],5F87_B Crystal structure of Drosophila Poglut1 (Rumi) complexed with UDP [Drosophila melanogaster],5F87_C Crystal structure of Drosophila Poglut1 (Rumi) complexed with UDP [Drosophila melanogaster],5F87_D Crystal structure of Drosophila Poglut1 (Rumi) complexed with UDP [Drosophila melanogaster],5F87_E Crystal structure of Drosophila Poglut1 (Rumi) complexed with UDP [Drosophila melanogaster],5F87_F Crystal structure of Drosophila Poglut1 (Rumi) complexed with UDP [Drosophila melanogaster]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q5K8R6|CXT1_CRYNJ	2.46e-94	116	632	152	661	Beta-1,2-xylosyltransferase 1 OS=Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) OX=214684 GN=CXT1 PE=1 SV=1
sp|G3V9D0|PGLT1_RAT	9.57e-15	511	628	261	371	Protein O-glucosyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Poglut1 PE=3 SV=1
sp|Q8NBL1|PGLT1_HUMAN	5.40e-14	511	628	261	371	Protein O-glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=POGLUT1 PE=1 SV=1
sp|Q5E9Q1|PGLT1_BOVIN	7.21e-14	511	628	261	371	Protein O-glucosyltransferase 1 OS=Bos taurus OX=9913 GN=POGLUT1 PE=2 SV=1
sp|Q8BYB9|PGLT1_MOUSE	4.05e-13	511	628	261	371	Protein O-glucosyltransferase 1 OS=Mus musculus OX=10090 GN=Poglut1 PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999959	0.000032

TMHMM  Annotations     

Start	End
5	27