CAZyme Information: CNBL2520-t26_1-p1

Basic Information

• Species: Cryptococcus neoformans
• Lineage: Arthropoda; Insecta; ; Eriococcidae; Cryptococcus; Cryptococcus neoformans
• CAZyme ID: CNBL2520-t26_1-p1
• CAZy Family: GT4
• CAZyme Description: unspecified product

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
851		94882.66	5.7312

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CneoformansB-3501A	6608	283643	108	6500

• Gene Location: location=CM000051:760186-763011(-)

Full Sequence      

MPLPPKVSPVTGNPVPPHYIHSSTLHFQDVNGRSLVLRGVNLSGSAKHPNNQPSHIREGF
WETAEAGKGDFINKPLNLDDGSADLHLARLKAWGYNLLRYVFTWESLEHAGPKEYDYAYM
DYIIAVLRKCKEWGFRVFMDPHQDVWSRFTGGSGAPLWTLYACGIDPYHLTPTAAAYLHC
EWPSAESPKPQDFPAMIWGTNYTHLANQTIWTFFFAGKTYAPKCIIDGKNIQDFLQDHFI
DAVGELAKRIAEEGGDLLDECVIGWDSVNEPGEGLIGYKDLAVIPAEQQLKKGPSPTPIE
GMRLGMGEVQDVQVWNFGPMGPYRGSRQTIDPKGVKLWLSEEDDVKRGSGKWGWTRGKEW
ALGTCIWAHHGVWDIATSTLLRPDYFSTLPTNPSHQVDFVDDFWALHWLAYSSRIRLHHP
ESIHFIQAPVLRQPPKLPESFLKGRACSSPHFYDGLTLMTKHWNWFNADAIGVIRKKYWS
IVQAVRIGEGPIRKMIQGELAVLKQDTVDILGKYPTLIGEIGIPYDMDDKKAYGYVDGGR
GEGDYSSQQKAMDCSMNACDGPNCLNYAIWNYVPDNVHEWGDNWNGEDLSLWSLDDKEQE
SYHDSPRSDTPNFSTNSSSLTNSSATLTVPMSGAAKLRLSPSVIDAGDFSPALILDGSRA
VAAFCRPYPVVTVGIPERIDFDITSTKFKYAVRVRADDIVNEQVYTEIYLPFVHYAASLD
PSRPAGHNPNSGQTALTSTDGDDSNLSSRQTSKVDLIEDERAIKSSDPSSISIRSVPYSS
STQLSLDVAIVASHGRVEIQGQTLRWWYPVPGTGEEVYTIEVQRNGGALRRDLGCVKASQ
YNGQTLINLSL

Enzyme Prediction     

EC	3.2.1.21:3	3.2.1.45:1	3.2.1.104:1

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH5	29	578	9.8e-212	0.9981447124304267

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
408348	Glyco_hydro_5_C	1.71e-07	666	715	1	48	Glycoside hydrolase family 5 C-terminal domain. This is the C-terminal domain of endo-glycoceramidase II (EGC), a membrane-associated family 5 glycosidase pfam00150. The C-terminal domain assumes a beta-sandwich fold, which resembles that of many carbohydrate-binding modules.
395098	Cellulase	4.82e-04	87	144	30	88	Cellulase (glycosyl hydrolase family 5).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AAW45118.1|GH5_12	0.0	1	851	1	851
AAW45117.1|GH5_12	0.0	1	841	1	841
AFR99035.1|GH5_12|3.2.1.104	0.0	1	841	1	841
AUB29264.1|GH5_12	0.0	1	841	1	841
UOH85036.1|GH5_12	0.0	1	841	1	841

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7LPO_A	0.0	1	841	2	787	Chain A, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPO_B Chain B, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPO_C Chain C, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPO_D Chain D, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPP_A Chain A, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPP_B Chain B, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPP_C Chain C, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPP_D Chain D, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPQ_A Chain A, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPQ_B Chain B, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPQ_C Chain C, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99],7LPQ_D Chain D, Cytoplasmic protein [Cryptococcus neoformans var. grubii H99]
2OSW_A	5.29e-08	26	165	36	161	Endo-glycoceramidase II from Rhodococcus sp. [Rhodococcus sp.],2OSW_B Endo-glycoceramidase II from Rhodococcus sp. [Rhodococcus sp.],2OYK_A Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like isofagomine complex [Rhodococcus sp.],2OYK_B Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like isofagomine complex [Rhodococcus sp.],2OYL_A Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like imidazole complex [Rhodococcus sp.],2OYL_B Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like imidazole complex [Rhodococcus sp.],2OYM_A Endo-glycoceramidase II from Rhodococcus sp.: five-membered iminocyclitol complex [Rhodococcus sp.],2OYM_B Endo-glycoceramidase II from Rhodococcus sp.: five-membered iminocyclitol complex [Rhodococcus sp.]
2OSX_A	5.29e-08	26	165	36	161	Chain A, Endoglycoceramidase II [Rhodococcus sp.]
2OSY_A	5.29e-08	26	165	36	161	Chain A, Endoglycoceramidase II [Rhodococcus sp.],2OSY_B Chain B, Endoglycoceramidase II [Rhodococcus sp.]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|H1AE13|EGCR1_ASPFM	1.76e-183	27	715	13	686	Glucosylceramidase OS=Neosartorya fumigata OX=746128 GN=egc1 PE=1 SV=1
sp|P40566|EGH1_YEAST	1.23e-147	17	727	2	715	Ergosteryl-beta-glucosidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=EGH1 PE=1 SV=1
sp|I1BTD7|EGCR1_RHIO9	9.12e-96	20	715	15	628	Glucosylceramidase OS=Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) OX=246409 GN=ERC1 PE=1 SV=1
sp|H1AE12|EGCR1_CRYNH	1.86e-68	26	711	22	635	Glucosylceramidase OS=Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) OX=235443 GN=EGC1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000069	0.000000

TMHMM  Annotations     

There is no transmembrane helices in CNBL2520-t26_1-p1.