CAZyme Information: CIHG_07780-t26_1-p1

Basic Information

• Species: Coccidioides immitis
• Lineage: Ascomycota; Eurotiomycetes; ; Onygenaceae; Coccidioides; Coccidioides immitis
• CAZyme ID: CIHG_07780-t26_1-p1
• CAZy Family: GT20
• CAZyme Description: beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
850		93918.89	7.2576

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CimmitisH538-4	10724	396776	186	10538

• Gene Location: location=DS017015:62293-64941(-)

Full Sequence      

MDNDELRRQLGQLFIVGFRSLIATDEVKSLIQAPYYCGTIILFQRNIESAEQLIALINDL
QQTARDAGHTRPLFIAVDQENGLVTRIKPPIATQLPGAMAVGATGDIDDAIRVSTATGEI
LDALGINMNYAPLCDVNSEPANPVIGVRSPGDDGTFVGRITSNIAKGLRKNSIVPCAKHF
PGHGSTKVDSHYGVPVVRKPKEDLEACELLPFRRAVAEGIEAIMTSHVVMSAFDDAGLPS
SVSKDVVNFLRRGLQHEGLIITDCLEMDAIRVQIGTEKGAVRALAAGVDCAMICHTYDVQ
VRALEEAFNACKIGTIPLRQISQSVSRVHALKDKFFDWDSVFRHRSVNTVTQLNLKHQEL
ANDIYARSVTVIRDDQKALPLSRGGSLVYVYPCGKALRVGASGSGETVTCVPYTPPEFSQ
ILKLFVPDLIECPFFDDATLDESTKSKISQADAVILASRNCRLNPSQRLIGTQLVNHSKK
LVSIATCVPYDFLNSGIKTCLAMYEPTVEAFQAAANVIFGVNEGVGKLPVCTKRPPLPID
SFDPERDMKLAINLWHMLLPHYAVPADRLHHLLDRPNGKHFTIYVEDQLAGFIATYVNED
RPTAYISVLLVHPKFRSRGVGTALVEHARRQLRGAARSVTIGSSFPRFFLGVPLDIPEEA
QNFFIHRGFVPSRGPSSRDYTADLRTYQPPEGVLQRAAAAGVTFTPWRINLYLECMANIR
ELWGDDEVWLGAYERLARQNRHEQVMVAMDRSGKQIGWTLMQELGLGMTNDLAFMPLLGQ
KTGQIGCLGIHPDARNKGVGLALVVSAAMDMKRRGLEKVFVDWTNHVNFYEKAGFEVWRE
YRSMTLKESV

Enzyme Prediction     

EC	3.2.1.52:8

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	71	292	9.5e-53	0.9537037037037037

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
224389	BglX	5.10e-72	6	390	3	359	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
395747	Glyco_hydro_3	8.23e-68	6	328	2	313	Glycosyl hydrolase family 3 N terminal domain.
235417	PRK05337	1.94e-45	24	339	14	314	beta-hexosaminidase; Provisional
395465	Acetyltransf_1	7.26e-11	560	669	15	116	Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.
404402	Acetyltransf_7	2.74e-10	576	671	1	83	Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QVM13647.1|GH3	0.0	1	850	1	850
QQK41162.1|GH3	2.06e-244	1	842	1	848
BCR85716.1|GH3	4.41e-244	1	842	1	850
CAP94355.1|GH3	2.66e-242	5	842	5	848
BCR93582.1|GH3	9.75e-239	6	846	6	857

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4ZM6_A	6.21e-133	2	842	5	854	A unique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain GH3 beta-N-acetylglucosaminidase [Rhizomucor miehei CAU432],4ZM6_B A unique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multi-domain GH3 beta-N-acetylglucosaminidase [Rhizomucor miehei CAU432]
6K5J_A	1.51e-81	6	529	13	528	Structure of a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
3BMX_A	4.69e-63	6	530	44	615	Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3BMX_B Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3NVD_A Structure of YBBD in complex with pugnac [Bacillus subtilis],3NVD_B Structure of YBBD in complex with pugnac [Bacillus subtilis]
3LK6_A	1.40e-62	6	530	18	589	Chain A, Lipoprotein ybbD [Bacillus subtilis],3LK6_B Chain B, Lipoprotein ybbD [Bacillus subtilis],3LK6_C Chain C, Lipoprotein ybbD [Bacillus subtilis],3LK6_D Chain D, Lipoprotein ybbD [Bacillus subtilis]
4GYJ_A	2.54e-62	6	530	48	619	Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYJ_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYK_A Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168],4GYK_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P40406|NAGZ_BACSU	2.41e-62	6	530	44	615	Beta-hexosaminidase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagZ PE=1 SV=1
sp|P48823|HEXA_PSEO7	6.18e-50	26	530	54	594	Beta-hexosaminidase A OS=Pseudoalteromonas piscicida OX=43662 GN=cht60 PE=1 SV=1
sp|L7N6B0|LPQI_MYCTU	2.68e-35	7	332	62	380	Beta-hexosaminidase LpqI OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=lpqI PE=1 SV=1
sp|A0A0H3M1P5|LPQI_MYCBP	6.64e-35	7	332	62	380	Beta-hexosaminidase LpqI OS=Mycobacterium bovis (strain BCG / Pasteur 1173P2) OX=410289 GN=lpqI PE=3 SV=1
sp|Q9K0Q4|NAGZ_NEIMB	2.68e-33	15	308	15	302	Beta-hexosaminidase OS=Neisseria meningitidis serogroup B (strain MC58) OX=122586 GN=nagZ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000035	0.000000

TMHMM  Annotations     

There is no transmembrane helices in CIHG_07780-t26_1-p1.