CAZyme Information: CIHG_02665-t26_1-p1

Basic Information

• Species: Coccidioides immitis
• Lineage: Ascomycota; Eurotiomycetes; ; Onygenaceae; Coccidioides; Coccidioides immitis
• CAZyme ID: CIHG_02665-t26_1-p1
• CAZy Family: GH13
• CAZyme Description: GPI mannosyltransferase 4

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
526		59581.01	8.9622

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CimmitisH538-4	10724	396776	186	10538

• Gene Location: location=DS016986:484729-486649(-)

Full Sequence      

MWRRTYLILLVIRIYFALSPSYLHPDENFQGPEIFAEQVYSYPAHLTWEFTSSKPIRSIF
PLWLSYGLPMTVLKWFWTETGSGSTPPYLIYYVLRGTMFGLSFVLEDWAIHELITSPRHR
REAVVLVASSYVTWTYQTHTFSNSLETLLVAWSLVVIQRILENKVGFTSMRAQNSPCVVT
TPFAFVSLALSGIIFSLVAIYADTRFYSSSPVSISDIFRKPIITPLNNLLYNSDKTNLAS
HGLHPHYQHFLINAPQLLGPVYVLLIASIFSRSSRSNFSLLNMRALSALTGTLILSVFPH
QESRFLIPCVPLLLTCFRLPNARVFLVTWIAFNSIMGLLLGVYHQGGIIPAQLQIPTIIS
NLNPGLEKAPASQETANVFWWKTYSPPLWLLGDAANITIKTHDLMGIPGRDMLEKLGKTV
PRCSDGSILRYPRFSGSKSNNDRRVVNPTLLVAPNSATFLDQYVRSENKDESQDDRLSLQ
LDPLWRYDCHLHLDDMDFGDDGILPTLKRVVGRRGLNVWLVTRACG

Enzyme Prediction     

EC	2.4.1.-:4	2.4.1.-:4

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT22	5	390	6.2e-70	0.9897172236503856

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
281842	Glyco_transf_22	5.54e-43	5	389	2	410	Alg9-like mannosyltransferase family. Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.
350723	DEADc_MRH4	0.002	79	233	69	223	DEAD-box helicase domain of ATP-dependent RNA helicase MRH4. Mitochondrial RNA helicase 4 (MRH4) plays an essential role during the late stages of mitochondrial ribosome or mitoribosome assembly by promoting remodeling of the 21S rRNA-protein interactions. MRH4 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QVM11889.1|GT22	0.0	1	526	1	552
QSS72479.1|GT22	4.37e-212	1	523	1	617
QSS55894.1|GT22	1.76e-211	1	523	1	617
QQK45046.1|GT22	2.70e-203	1	525	1	522
BCS03934.1|GT22	1.45e-201	1	524	1	534

PDB Hits     

CIHG_02665-t26_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q5BAX7|SMP3_EMENI	4.35e-198	1	523	1	538	GPI mannosyltransferase 4 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=smp3 PE=3 SV=2
sp|Q4WTT7|SMP3_ASPFU	1.47e-196	1	524	1	544	GPI mannosyltransferase 4 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=smp3 PE=3 SV=2
sp|Q2UTP0|SMP3_ASPOR	7.88e-193	1	524	1	540	GPI mannosyltransferase 4 OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=smp3 PE=3 SV=1
sp|Q4I785|SMP3_GIBZE	3.43e-162	1	525	1	515	GPI mannosyltransferase 4 OS=Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) OX=229533 GN=SMP3 PE=3 SV=2
sp|Q6CDD0|SMP3_YARLI	2.52e-69	10	392	13	398	GPI mannosyltransferase 4 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=SMP3 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.250940	0.749038	CS pos: 23-24. Pr: 0.3505

TMHMM  Annotations     

Start	End
178	200
252	274
325	347