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CAZyme Information: CDH53051.1
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Lichtheimia corymbifera | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Mucoromycota; Mucoromycetes; ; Lichtheimiaceae; Lichtheimia; Lichtheimia corymbifera | |||||||||||
| CAZyme ID | CDH53051.1 | |||||||||||
| CAZy Family | GH27 | |||||||||||
| CAZyme Description | glycoside hydrolase family 5 protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | ||||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH5 | 47 | 380 | 2.1e-83 | 0.9930795847750865 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| 226444 | COG3934 | 4.31e-18 | 27 | 433 | 63 | 469 | Endo-1,4-beta-mannosidase [Carbohydrate transport and metabolism]. |
| 408204 | Serine_protease | 1.82e-04 | 116 | 231 | 135 | 253 | Gammaproteobacterial serine protease. This family includes serine proteases such as L. pneumophila effector Lpg1137. Lpg1137, is a serine protease that targets the mitochondria-associated ER membrane (MAM) and degrades STX17 (syntaxin 17), a SNARE implicated in macroautophagy/autophagy as well as mitochondria dynamics and membrane trafficking in fed cells. Lpg1137 has a sequence (-Gly-Leu-Ser68-Gly-Gly-) that matches the consensus sequence for the active site of serine proteases (Gly-X-Ser-X-Gly/Ala, where X is any residue). It exhibits proteolytic activity toward STX17 in vitro, whereas an active site mutant in which Ser68 is replaced by Ala does not. Expressed Lpg1137 localizes to the MAM and mitochondria, in addition to the cytosol, and binds to STX17. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| 2.45e-302 | 3 | 435 | 24 | 436 | |
| 2.45e-302 | 3 | 435 | 24 | 436 | |
| 3.21e-233 | 3 | 433 | 34 | 443 | |
| 1.70e-227 | 2 | 435 | 35 | 447 | |
| 3.31e-125 | 4 | 432 | 38 | 476 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 2.18e-226 | 5 | 435 | 37 | 446 | Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase from Rhizomucor miehei [Rhizomucor miehei],4LYP_B Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase from Rhizomucor miehei [Rhizomucor miehei] |
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| 1.78e-225 | 5 | 435 | 37 | 446 | Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase from Rhizomucor miehei, E202A mutant [Rhizomucor miehei],4NRR_A Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase (E202A mutant) from Rhizomucor miehei in complex with mannosyl-fructose [Rhizomucor miehei],4NRR_B Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase (E202A mutant) from Rhizomucor miehei in complex with mannosyl-fructose [Rhizomucor miehei],4NRS_A Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase (E202A mutant) from Rhizomucor miehei in complex with mannobiose [Rhizomucor miehei],4NRS_B Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase (E202A mutant) from Rhizomucor miehei in complex with mannobiose [Rhizomucor miehei] |
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| 1.78e-225 | 5 | 435 | 37 | 446 | Glycoside Hydrolase Family 5 Mannosidase from Rhizomucor miehei, E301A mutant [Rhizomucor miehei] |
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| 2.59e-83 | 6 | 426 | 24 | 426 | Exo-mannosidase from Cellvibrio mixtus [Cellvibrio mixtus],1UZ4_A Common inhibition of beta-glucosidase and beta-mannosidase by isofagomine lactam reflects different conformational intineraries for glucoside and mannoside hydrolysis [Cellvibrio mixtus],7ODJ_AAA Chain AAA, Man5A [Cellvibrio mixtus] |
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| 6.76e-29 | 9 | 405 | 7 | 360 | Chain A, endo-beta-mannanase [Solanum lycopersicum] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4.20e-31 | 9 | 308 | 2 | 296 | Mannan endo-1,4-beta-mannosidase 8 OS=Oryza sativa subsp. japonica OX=39947 GN=MAN8 PE=2 SV=2 |
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| 1.43e-29 | 3 | 402 | 36 | 392 | Mannan endo-1,4-beta-mannosidase 5 OS=Solanum lycopersicum OX=4081 GN=MAN5 PE=2 SV=1 |
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| 1.43e-29 | 3 | 402 | 36 | 392 | Mannan endo-1,4-beta-mannosidase 2 OS=Solanum lycopersicum OX=4081 GN=MAN2 PE=2 SV=2 |
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| 1.25e-28 | 9 | 311 | 30 | 325 | Mannan endo-1,4-beta-mannosidase 1 OS=Arabidopsis thaliana OX=3702 GN=MAN1 PE=2 SV=1 |
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| 5.12e-28 | 9 | 405 | 33 | 386 | Mannan endo-1,4-beta-mannosidase 4 OS=Solanum lycopersicum OX=4081 GN=MAN4 PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | CS Position |
|---|---|---|
| 1.000034 | 0.000000 |