CAZyme Information: CCE27564.1

Basic Information

• Species: Claviceps purpurea
• Lineage: Ascomycota; Sordariomycetes; ; Clavicipitaceae; Claviceps; Claviceps purpurea
• CAZyme ID: CCE27564.1
• CAZy Family: AA5
• CAZyme Description: Related to KRE5-killer toxin-resistance protein [Source:UniProtKB/TrEMBL;Acc:M1WA97]

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1477	CAGA01000004|CGC3	165916.43	5.1590

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_Cpurpurea20.1	8979	1111077	156	8823

• Gene Location: location=CAGA01000004:809223-813828(+)

Full Sequence      

MFLILEQWPLLLWLALVARVVAVPAVRVGMTAAFNAGPYLLELIETAAGENTSSYFPILD
RVASGYFSEASSDSDLYDQFLGVLRNDGHIKDPDALSTFNLALSLRSAAPRIEAHYQYYR
TAIEPFVEHRNCEVWVLFDRKQYCTPDLDIVVRDELFSAIVKTLPFDRTIGIGREAILFA
DPTSSKFAQYHQKLSKAARALALNYRIRYRRDNAGLDRPLQIGGYGVQLALKNTDYIVID
DRRTVQDVDQKPLGPSTVLEDEDQDSMNLKTLSKTELRSVGMRAASYVQQSETPFDELVK
LSQDFPKHVRYMSSQNISSAFAGEYERIKARMVRNGVNFLWMNGAQLTDRQIDPFTLVDV
LRRERSLVNGIRELGVNGADAIALLSHQAVSSAQGEQESSRYDWTDRSENGQVILWFNNL
ERDDTYDSYPKTLSSLLQRTYPGQIPPVRLNVFNMVFAADLSNTEDLHFMSQVIGLVNRG
IPIRFGFVPLQTTSDATSQAKAAYALVKNYGIETLISYIEQLSSKGGVFDESLLLSVTNG
RPVFSDSLSMSADGETRGMEVDEQLELSSKWVARLQADTLVRPLFVNGVLVPRDQNWMRS
ISIIIGDDLQTVQQGIYLGTLDDDSPINGLFLSEARPRRNTYIFQGENKSLRMLNVGKIY
ADNKEFFETLPVLNANEYATKEDWAAMTVLANMSSTAGLDLTLSALTFKRSNPAVRIDII
NTHGDLSVSSQVISALKSKENGLLNLRSIEDLQSIVLEASNFDASGVYAQGLTNVLGDAK
LMPGSQGIFLNGRVIGPIAPEFSFSSEDFQDLLAFERTQRILPVFAAAEDLGLTDVISGP
IAAAKLSSIVALSTISAVPEGIFDSAPSTRSTLYDVWNTTHTAIQAGDSKAASIHIIGCL
DPASEIAQRWAPILRAVSKLHGVYIKIILNPQEKLEELPVKRFYRYVIDSQPTFEKDGSL
KLNQATFAGLPSDVLMTAGLDVPPAWLVAPKSSIHDLDNIKLDMAESDVDATYQLQHILI
EGHSREGTGSPPRGAQLVLATEAQPDITDTIIMANLGFFQFKANPGLYHIQLKDGRSRDL
YSIESIGAHGWEPALGDEGTELVLMDFQGITVYPRLKRHLGMEEHDVLENPEQDVDTSLL
TKGLKLAERFLGKGKQDLSEPKHADINIFSVASGHLYERMLSIMILSVMRNTKHTVKFWF
IEQFLSPSFKQFIPHLAEAYRFTYEMVTYKWPHWLRQQKEKQREIWGYKILFLDVLFPLS
LDKVIFVDADQIVRTDMMNLVNLDLHGAPYGFTPMCDSRVEMEGFRFWKQGYWANYLRGK
PYHISALYVVDLRRFRELAAGDRLRQQYHALSADPGSLSNLDQDLPNHMQFQIPIHSLPQ
EWLWCETWCSDDSLKKAHTIDLCNNPLTKEPKLDRARRQVPEWTTYDDEIAVLEAEKGLG
RARETRSNFDHEVSQVAEPAKKPAEKPNQGVHQMDEL

Enzyme Prediction     

EC	2.4.1.-:29

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT24	1166	1413	9.5e-134	0.9959677419354839

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
133054	GT8_HUGT1_C_like	0.0	1166	1413	1	248	The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity.
408203	Glyco_transf_24	0.0	1166	1433	1	268	Glucosyltransferase 24. This is the catalytic domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT). This domain belongs to glucosyltransferase 24 family (GT24) A-type domain. The GT domain displays the expected glycosyltransferase type A (GT-A) fold.
408201	Thioredoxin_14	1.56e-81	402	643	1	248	Thioredoxin-like domain. This is the third out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
408202	Thioredoxin_15	1.91e-61	655	851	1	204	Thioredoxin-like domain. This is the fourth TRXL(thioredoxin-like) domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
399437	UDP-g_GGTase	8.07e-57	1021	1129	1	109	UDP-glucose:Glycoprotein Glucosyltransferase. UDP-g_GGTase is an important, central component of the QC system in the ER for checking that glycoproteins are folded correctly. This QC prevents incorrectly folded glycoproteins from leaving the ER.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QPG93890.1|GT24	0.0	1	1477	1	1477
QUC23668.1|GT24	0.0	1	1434	1	1438
QLI68466.1|GT24	0.0	8	1437	8	1439
ANH56544.1|GT24	0.0	7	1455	7	1462
UNI17283.1|GT24	0.0	25	1477	25	1477

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5MU1_A	0.0	19	1433	4	1447	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5MZO_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TRF_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
5NV4_A	0.0	19	1433	4	1447	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TRT_A	0.0	19	1433	4	1447	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS2_A	0.0	19	1433	4	1213	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_C Chain C, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_D Chain D, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS8_A	0.0	24	1375	2	1382	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS8_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q09140|UGGG_SCHPO	3.24e-263	28	1433	24	1424	UDP-glucose:glycoprotein glucosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=gpt1 PE=1 SV=2
sp|Q9NYU2|UGGG1_HUMAN	7.40e-233	25	1434	46	1524	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3
sp|Q6P5E4|UGGG1_MOUSE	3.04e-229	25	1434	46	1524	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Mus musculus OX=10090 GN=Uggt1 PE=1 SV=4
sp|Q9JLA3|UGGG1_RAT	1.91e-225	25	1434	46	1524	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Uggt1 PE=1 SV=2
sp|Q09332|UGGG_DROME	2.15e-221	38	1433	42	1507	UDP-glucose:glycoprotein glucosyltransferase OS=Drosophila melanogaster OX=7227 GN=Uggt PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.781721	0.218294

TMHMM  Annotations     

There is no transmembrane helices in CCE27564.1.