CAZyme Information: C7_02970W_B-T-p1

Basic Information

• Species: Candida albicans
• Lineage: Ascomycota; Saccharomycetes; ; Debaryomycetaceae; Candida; Candida albicans
• CAZyme ID: C7_02970W_B-T-p1
• CAZy Family: GT58
• CAZyme Description: Putative mannosyltransferase similar to S. cerevisiae Ecm39p, which has a role in Calcofluor white resistance, predicted Kex2p substrate, has HKEXRF motif

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
584		66221.89	6.6396

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CalbicansSC5314_B	6415	N/A	215	6200

• Gene Location: location=Ca22chr7B_C_albicans_SC5314:642611-644365(+)

Full Sequence      

MYRYNKVLDATLIALVSFHLVISPFTKVEESFNIQAIHDILKFGIFPFETIDNYDHKQFP
GVVPRTFLGSLVVAGLAKPILLLSSAFGFEIEGYELQKLVRAVLGLVNVLMLIRLRDSIN
KITFSDKKSKRKGLIGFWYTTLLLSQFHLLYYSSRTLPNFIALPLVNFSLSKIIQGDLSG
LTWLAFTGIVFRLEVGLFGLIIAIVSSLGFGQSNIFGNIIYLAMGTLLGGFTSFCIDSYF
WGRPLIPEIDSFIFNIVQGKSTEWGTEPWDTYFKKYLFQLFRPPVILMLAIPGSINDPAN
DGTKFGDKKSVPHPARYSLRILFISSILFIAAMSFQPHKEWRFIVYTIPIFTLQAANGVT
NICQKWGLSVLNKVLIFIIGANVIISSLLSLHMGYISSFNYPGGDALQFTNNYILENYKN
ETVSVHMDVPACMTGITRFGELDGKFASYDKSEQDFDITNYDIIITHNEVPNWELLHSSR
VFDGISLRMFIQIFMAQRKDRSTIFNITKLILSEFAQGEFGTVHDMLRSTITTVEYLNVY
KNVNKNPHIVQGVPETEIIDQEIDPEEIRQDVNEQIDKFESAVL

Enzyme Prediction     

No EC number prediction in C7_02970W_B-T-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT22	11	419	4.7e-88	0.9177377892030848

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
281842	Glyco_transf_22	1.99e-32	11	395	2	368	Alg9-like mannosyltransferase family. Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AOW30643.1|GT22	0.0	1	584	1	584
BAE44802.1|GT22	0.0	1	584	1	584
CAX40814.1|GT22	0.0	1	584	1	584
CCG25115.1|GT22	2.16e-244	1	551	25	578
CCE45406.1|GT22	6.46e-243	1	546	1	549

PDB Hits     

C7_02970W_B-T-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P53730|ALG12_YEAST	4.06e-99	6	546	4	547	Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=ALG12 PE=1 SV=1
sp|Q9USD4|ALG12_SCHPO	5.05e-55	23	468	27	431	Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=alg12 PE=3 SV=2
sp|Q9BV10|ALG12_HUMAN	1.11e-54	12	453	17	418	Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG12 PE=1 SV=1
sp|Q8VDB2|ALG12_MOUSE	2.04e-53	12	453	18	417	Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Mus musculus OX=10090 GN=Alg12 PE=2 SV=2
sp|Q23361|ALG12_CAEEL	2.28e-52	19	465	15	430	Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Caenorhabditis elegans OX=6239 GN=algn-12 PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.464885	0.535103	CS pos: 28-29. Pr: 0.3499

TMHMM  Annotations     

Start	End
67	89
99	113
133	152
188	210
219	241
278	295
316	333
343	362
374	396