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CAZyme Information: C2_10160W_A-T-p1

You are here: Home > Sequence: C2_10160W_A-T-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Candida albicans
Lineage Ascomycota; Saccharomycetes; ; Debaryomycetaceae; Candida; Candida albicans
CAZyme ID C2_10160W_A-T-p1
CAZy Family GH3
CAZyme Description Secreted protein, fluconazole-induced
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
418 Ca22chr2A_C_albicans_SC5314|CGC10 47337.64 6.1379
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_CalbicansSC5314 6468 237561 256 6212
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in C2_10160W_A-T-p1.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH76 55 336 2.8e-42 0.8100558659217877

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
397638 Glyco_hydro_76 1.37e-23 82 313 35 294
Glycosyl hydrolase family 76. Family of alpha-1,6-mannanases.
227170 COG4833 3.34e-07 124 266 87 227
Predicted alpha-1,6-mannanase, GH76 family [Carbohydrate transport and metabolism].
271200 LanM-like 5.67e-04 139 308 503 650
Cyclases involved in the biosynthesis of class II lantibiotics, and similar proteins. LanM-like proteins. LanM is a bifunctional enzyme, involved in the synthesis of class II lantibiotics. It is responsible for both the dehydration and the cyclization of the precursor-peptide during lantibiotic synthesis. The C-terminal domain shows similarity to LanC, the cyclase component of the lan operon, but the N terminus seems to be unrelated to the dehydratase, LanB.
399566 C5-epim_C 6.92e-04 134 269 33 179
D-glucuronyl C5-epimerase C-terminus. This family represents the C-terminus of D-glucuronyl C5-epimerase (EC:5.1.3.-). Glucuronyl C5-epimerases catalyze the conversion of D-glucuronic acid (GlcUA) to L-iduronic acid (IdceA) units during the biosynthesis of glycosaminoglycans.
271198 LanC_like 0.003 135 293 57 202
Cyclases involved in the biosynthesis of lantibiotics, and similar proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain thioether cross-links called lanthionines (Lans) or methyllanthionines (MeLans), in addition to 2,3-didehydroalanine (Dha) and (Z)-2,3-didehydrobutyrine (Dhb). These unusual amino acids are introduced by the dehydration of serine and threonine residues, followed by thioether formation via addition of cysteine thiols, catalysed by LanB and LanC or LanM. LanC, the cyclase component, is a zinc metalloprotein, whose bound metal has been proposed to activate the thiol substrate for nucleophilic addition. A related domain is also present in LanM and other pro- and eukaryotic proteins with poorly characterized functions.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
4.45e-312 1 418 1 418
2.19e-188 2 415 3 410
2.04e-147 8 416 3 400
2.96e-107 34 415 20 383
6.94e-106 39 417 25 385

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.43e-12 128 347 133 365
Structure of the GH76A alpha-1,6-mannanase from Salegentibacter sp. HEL1_6 [Salegentibacter sp. Hel_I_6],6SHD_B Structure of the GH76A alpha-1,6-mannanase from Salegentibacter sp. HEL1_6 [Salegentibacter sp. Hel_I_6],6SHD_C Structure of the GH76A alpha-1,6-mannanase from Salegentibacter sp. HEL1_6 [Salegentibacter sp. Hel_I_6]
1.91e-12 140 347 146 366
An inactive (D136A and D137A) variant of alpha-1,6-mannanase, GH76A of Salegentibacter sp. HEL1_6 in complex with alpha-1,6-mannotetrose [Salegentibacter sp. Hel_I_6]
1.91e-12 140 347 146 366
Chain A, Alpha-1,6-endo-mannanase GH76A mutant [Salegentibacter sp. Hel_I_6]
2.34e-06 184 310 202 326
Structure of the GH76 alpha-mannanase BT2949 from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],4V1S_B Structure of the GH76 alpha-mannanase BT2949 from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3.72e-11 81 260 46 248
Meiotically up-regulated gene 191 protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mug191 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000191 0.999787 CS pos: 20-21. Pr: 0.9809

TMHMM  Annotations      download full data without filtering help

Start End
7 24