CAZyme Information: B9J08_005077-t37_1-p1

Basic Information

• Species: [Candida] auris
• Lineage: Ascomycota; Saccharomycetes; ; Debaryomycetaceae; Candida; [Candida] auris
• CAZyme ID: B9J08_005077-t37_1-p1
• CAZy Family: GT71
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
969		111069.14	5.4873

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CaurisB8441	5584	N/A	167	5417

• Gene Location: location=PEKT02000010:397101-400010(-)

Full Sequence      

MAYRRSSEDDEQRYLRYPSTQTGGVYNYSNDAVDSINFQQPQRVYSSQMHQSNDDFLHYY
EDERPSAMFNTSHVPPPPPRTQPLPSHDPFTDNDFEMGSYPQTQYQPTAYDPDSTGYNFS
QAFVPHVYDDEEEQQFDREIQFNQFQGDNLDLQTVHVADSDSEQDGRTVYDQELESPFAE
VGEDFPEPPEQEEVRQKPKLGIATGHNGHLVLDCPVATELLTKFPDYDASKPDGGLSREF
SYMRYTAVTCGPSNFWRDGYILRPIHYPVRRQTEMMVVITMYNEDDILLARTLKGVFKNI
KHLESRSRSPVWGRDSWKKVVVCVVSDGRSKINERAQALLAALGVYQEGLAKSRIDDKKV
QGHIYEYTTRVGISSVEDTVKLTTEKVVPVQMLFCLKENNAKKINSHRWCFEALSQVLDP
NIVVLLDCGTQPSGKSLYHLWKEFDKDPRVAGACGEIKASLKKRQMLTNPIVYGQNFEYK
ISNILDKPTESVFGFISVLPGAFSAYRYVALQNDINGKGPLEKYFKGEFLHGSGELDPND
DEYDLKVKMLKEEAGIFTSNMYLAEDRILCYELVAKPGCSWVLRYCKSASAETDVPEGLA
EFILQRRRWLNGSFFAAIYSLAHFYKIWHSSHSFGKKIMFHVEFFYQLINLVVSWFSIGS
YFLVFRILTTSLSDESLNFAPGNVLSVIFLWLYLASIVTTFVLSFGNKPKGTEKFYIVIV
CFFAILMAYMIFAAIFMAVNAIQSIYNTNQGVSVSLFFKNEQFRDLVVATCSTYALYFIA
SFLYFEPWHMFTSFVQYILLSPSYINVLNIYAFCNIDDISWGTKGDTGATDLGAAKVRED
GTFDVNIPVLKEEINQSYLNQLEKIKKPRDDDGGKYHATNEDYYAFVRSMTVLIWMISNF
VIVAIVLETGGFNQFNKNEDSDVIKSARSKVFLTVILWTVAFMALFRFIGCTTYLIFRFM
DKFRSRAKM

Enzyme Prediction     

EC	2.4.1.16:26	2.4.1.16:26

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	281	444	2e-71	0.9938650306748467
GT2	422	687	2.6e-18	0.4478178368121442

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396286	Chitin_synth_1	7.94e-99	281	444	1	163	Chitin synthase. This region is found commonly in chitin synthases classes I, II and III. Chitin a linear homopolymer of GlcNAc residues, it is an important component of the cell wall of fungi and is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases.
133033	Chitin_synth_C	1.00e-85	277	616	1	244	C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin. Chitin synthase, also called UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase, catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of GlcNAc residues formed by covalent beta-1,4 linkages. Chitin is an important component of the cell wall of fungi and bacteria and it is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. Studies with fungi have revealed that most of them contain more than one chitin synthase gene. At least five subclasses of chitin synthases have been identified.
400626	Chitin_synth_1N	3.24e-26	207	280	6	70	Chitin synthase N-terminal. This is the N-terminal domain of Chitin synthase (pfam01644).
224136	BcsA	3.75e-22	393	737	115	402	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
133045	CESA_like	3.88e-14	277	511	1	166	CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QWW24830.1|GT2	0.0	1	969	1	969
QEL62108.1|GT2	0.0	1	969	1	969
QEO22981.1|GT2	0.0	1	969	1	969
QRG39444.1|GT2	0.0	1	969	1	969
QWU89335.1|GT2	0.0	1	965	1	960

PDB Hits     

B9J08_005077-t37_1-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P30572|CHS2_CANAX	0.0	2	958	17	996	Chitin synthase 2 OS=Candida albicans OX=5476 GN=CHS2 PE=2 SV=2
sp|P30583|CHSC_EMENI	5.34e-272	208	958	185	913	Chitin synthase C OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=chsC PE=3 SV=3
sp|P30588|CHS3_NEUCR	1.15e-268	206	958	156	883	Chitin synthase 3 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=chs-3 PE=3 SV=2
sp|P30601|CHS2_EXODE	2.17e-268	207	958	193	916	Chitin synthase 2 OS=Exophiala dermatitidis OX=5970 GN=CHS2 PE=3 SV=2
sp|Q12564|CHSA_AMPQU	1.18e-257	208	958	171	897	Chitin synthase A OS=Ampelomyces quisqualis OX=50730 GN=CHSA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000028	0.000001

TMHMM  Annotations     

Start	End
609	628
648	670
685	707
716	738
766	785
885	907
935	957