CAZyme Information: An16g05970-T-p1

Basic Information

• Species: Aspergillus niger
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus niger
• CAZyme ID: An16g05970-T-p1
• CAZy Family: GT31
• CAZyme Description: Putative UDP-glucuronosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
542	An16_A_niger_CBS_513_88|CGC6	60942.40	6.8225

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AnigerCBS513-88	14403	425011	346	14057

• Gene Location: location=An16_A_niger_CBS_513_88:1328601-1330293(-)

Full Sequence      

MAMSDIILPPRKILLVVTGGGYTHAAPVLELGKVLANRGHVVDFATLDGQEEWASGFQIS
STHLMGPGPTEEQLDAHYMRSRLWDPARGLGDVMESKYLFDSLWTQSYYGLKTIMDDPAT
RPDMLVADFFVDAVKDIQLEYKVPIAIVWPQMPYLMVPCSYIPGQPGFQLDMTLTSENAS
MWSRINNELVVVRALPEVFKLRNWTRAMRKRAGLNYLLPTPKKPDYLLLVNSFFGLEVPK
DLPPLVAAVGPILADEYPLLDAPHQEFLDRHPKTIYIALGTHIILPHADARKILQGLIQA
MEEGVIDGVIWSVGRSGRQLFDNAESFTMQGKTISFGDLLEGLHADWKFPFFAPQRSILD
HPHTRIYFTHGGGSSANEGLYHGKPMLVMSFFFDQIGNAAKLAGNGTSELLHKFRFTADE
LYFKTKLIMEDRDGCYARNVQRLQRIAHVASRRKYLGADLIEEVLYDNESRVVDGKETRP
MHLQTADMRMPAYKAKNWDLMAVSGVVMGLLGGGLYYAGRLAWINRRAIDGFVDGLVCKI
YN

Enzyme Prediction     

No EC number prediction in An16g05970-T-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT1	114	447	2.9e-26	0.7094240837696335

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
340817	GT1_Gtf-like	1.49e-40	15	463	4	403	UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.
224732	YjiC	8.45e-19	12	465	3	399	UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism].
278624	UDPGT	2.66e-12	353	448	330	423	UDP-glucoronosyl and UDP-glucosyl transferase.
177813	PLN02152	9.21e-08	116	452	104	438	indole-3-acetate beta-glucosyltransferase
223071	egt	1.86e-07	354	446	355	445	ecdysteroid UDP-glucosyltransferase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CAK46937.1|GT1	0.0	1	542	1	527
QKD56593.1|GT1	2.67e-248	9	539	6	538
QLI65751.1|GT1	3.92e-242	10	536	5	533
QKX59607.1|GT1	1.21e-235	9	537	8	541
BCR88254.1|GT1	8.62e-233	3	528	1	532

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6IPB_A	3.17e-11	280	448	19	191	Crystal Structure of the Cofactor-binding Domain of the Human Phase II Drug Metabolism Enzyme UGT2B15 [Homo sapiens],6IPB_B Crystal Structure of the Cofactor-binding Domain of the Human Phase II Drug Metabolism Enzyme UGT2B15 [Homo sapiens],6IPB_C Crystal Structure of the Cofactor-binding Domain of the Human Phase II Drug Metabolism Enzyme UGT2B15 [Homo sapiens],6IPB_D Crystal Structure of the Cofactor-binding Domain of the Human Phase II Drug Metabolism Enzyme UGT2B15 [Homo sapiens]
7CJX_A	1.64e-08	354	442	78	164	Chain A, UDP-glucuronosyltransferase 2B15 [Homo sapiens],7CJX_B Chain B, UDP-glucuronosyltransferase 2B15 [Homo sapiens],7CJX_C Chain C, UDP-glucuronosyltransferase 2B15 [Homo sapiens],7CJX_D Chain D, UDP-glucuronosyltransferase 2B15 [Homo sapiens]
5NLM_A	2.53e-07	121	402	116	403	Chain A, indoxyl UDP-glucosyltransferase [Persicaria tinctoria],5NLM_B Chain B, indoxyl UDP-glucosyltransferase [Persicaria tinctoria]
6SU6_A	2.61e-07	121	402	137	424	Complex between a UDP-glucosyltransferase from Polygonum tinctorium capable of glucosylating indoxyl and UDP-glucose [Persicaria tinctoria],6SU6_B Complex between a UDP-glucosyltransferase from Polygonum tinctorium capable of glucosylating indoxyl and UDP-glucose [Persicaria tinctoria],6SU7_A Complex between a UDP-glucosyltransferase from Polygonum tinctorium capable of glucosylating indoxyl and 3,4-Dichloroaniline [Persicaria tinctoria],6SU7_B Complex between a UDP-glucosyltransferase from Polygonum tinctorium capable of glucosylating indoxyl and 3,4-Dichloroaniline [Persicaria tinctoria],6SU7_C Complex between a UDP-glucosyltransferase from Polygonum tinctorium capable of glucosylating indoxyl and 3,4-Dichloroaniline [Persicaria tinctoria],6SU7_D Complex between a UDP-glucosyltransferase from Polygonum tinctorium capable of glucosylating indoxyl and 3,4-Dichloroaniline [Persicaria tinctoria]
6PNT_A	6.74e-06	352	431	324	401	Structural Characterization of UDP-glycosyltransferase from Tetranychus Urticae [Tetranychus urticae]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P06133|UD2B4_HUMAN	1.64e-13	155	448	187	450	UDP-glucuronosyltransferase 2B4 OS=Homo sapiens OX=9606 GN=UGT2B4 PE=1 SV=2
sp|O02663|UD2B9_MACFA	1.65e-13	92	448	129	450	UDP-glucuronosyltransferase 2B9 OS=Macaca fascicularis OX=9541 GN=UGT2B9 PE=2 SV=1
sp|P36537|UDB10_HUMAN	3.83e-13	158	448	189	449	UDP-glucuronosyltransferase 2B10 OS=Homo sapiens OX=9606 GN=UGT2B10 PE=1 SV=1
sp|O75310|UDB11_HUMAN	5.08e-13	155	448	187	450	UDP-glucuronosyltransferase 2B11 OS=Homo sapiens OX=9606 GN=UGT2B11 PE=1 SV=1
sp|O97951|UDB18_MACFA	5.08e-13	156	448	188	450	UDP-glucuronosyltransferase 2B18 OS=Macaca fascicularis OX=9541 GN=UGT2B18 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000055	0.000001

TMHMM  Annotations     

Start	End
497	519