dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: An12g01880-T-p1

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Basic Information help

Species

Aspergillus niger

Lineage

Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus niger

CAZyme ID

An12g01880-T-p1

CAZy Family

GH53

CAZyme Description

Ortholog(s) have mannosyltransferase activity, role in GPI anchor biosynthetic process, fungal-type cell wall organization and glycosylphosphatidylinositol-mannosyltransferase I complex localization

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
418	An12_A_niger_CBS_513_88\|CGC14	46800.79	9.5990

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AnigerCBS513-88	14403	425011	346	14057

Gene Location

Full Sequence Download help

Enzyme Prediction help

EC	2.4.1.-:14

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GT50	135	368	2.5e-82	0.8473282442748091

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
178434	PLN02841	1.84e-75	8	368	9	376	GPI mannosyltransferase
252941	Mannosyl_trans	2.58e-59	135	367	1	219	Mannosyltransferase (PIG-M). PIG-M has a DXD motif. The DXD motif is found in many glycosyltransferases that utilize nucleotide sugars. It is thought that the motif is involved in the binding of a manganese ion that is required for association of the enzymes with nucleotide sugar substrates.
399599	PIG-U	9.75e-07	47	258	39	243	GPI transamidase subunit PIG-U. Many eukaryotic proteins are anchored to the cell surface via glycosylphosphatidylinositol (GPI), which is posttranslationally attached to the carboxyl-terminus by GPI transamidase. The mammalian GPI transamidase is a complex of at least four subunits, GPI8, GAA1, PIG-S, and PIG-T. PIG-U is thought to represent a fifth subunit in this complex and may be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
401508	GT87	6.11e-04	66	187	3	122	Glycosyltransferase family 87. The enzymes in this family are glycosyltransferases. PimE is involved in phosphatidylinositol mannoside (PIM) synthesis, a major class of glycolipids in all mycobacteria. PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of PIM. The family also includes alpha(1-->3) arabinofuranosyltransferase, invloved in the synthesis of of mycobacterial arabinogalactan.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start
1.41e-299	1	418	1	418
8.83e-240	2	393	9	387
8.83e-240	2	393	9	387
2.27e-198	1	367	1	366
5.55e-198	1	367	26	391

PDB Hits help

An12g01880-T-p1 has no PDB hit.

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
4.03e-199	1	367	1	366	GPI mannosyltransferase 1 OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=gpi14 PE=3 SV=2
6.77e-186	1	393	1	389	GPI mannosyltransferase 1 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=gpi14 PE=3 SV=1
2.81e-182	1	367	1	384	GPI mannosyltransferase 1 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=gpi14 PE=3 SV=1
5.59e-143	1	367	19	441	GPI mannosyltransferase 1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=gim-1 PE=3 SV=1
2.74e-135	1	367	4	364	GPI mannosyltransferase 1 OS=Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) OX=229533 GN=GPI14 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.923846	0.076170

TMHMM Annotations download full data without filtering help

Start	End
10	28
69	88
92	114
135	157
167	189
222	244
289	306
318	340
355	377