CAZyme Information: Afu2g09520-T-p1

Basic Information

• Species: Aspergillus fumigatus
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus fumigatus
• CAZyme ID: Afu2g09520-T-p1
• CAZy Family: GH1
• CAZyme Description: Endo-beta-1,4-mannanase F, putative

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
477		50811.87	4.3808

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AfumigatusAf293	10130	330879	290	9840

• Gene Location: location=Chr2_A_fumigatus_Af293:2436842-2438523(-)

Full Sequence      

MRISSLIMAASAAGLVSALPVREMTKKRSSGFTWVGINESGAEFGSNIPGKLGTDYTWPD
TSKIQTLRDAGMNIFRVPFLMERLVPSSITGNLDATYLSDLKKTVEFITGSGAYAVLDPH
NYGRYSGSIISSTSDFQEFWKTVASEFASNDKVIFDTNNEYHDMDQTLVLNLNQAAINGI
RAAGATTQYIFVEGNHYSGAWTWADNNDNLKGLKDPEDKIVFEMHQYLDSDGSGTSESCV
SSTIGQERVESATQWLKDNSLKGFLGEFAGGVNSQCETAVEGLLSYMSENSDVWLGAEWW
SAGPMWGNYMYSLEPSTGPAYSSYLPILKNYFVSGTSSSSSSSSSITSSTTSVNNPTTSA
TTQAQVVNTSSSSPTPSPTSVPAAEAPAPTPTEAAKTSSAASTTPTTAAASTTASACRAP
EPADETTLPSATPTTSASASGIAKHWYQCGGINWTGPTTCESGYTCVEQNPYYHQCV

Enzyme Prediction     

EC	3.2.1.4:38

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH5	34	310	7.5e-116	0.9964539007092199
CBM1	445	473	6.3e-16	0.9655172413793104

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
395098	Cellulase	1.33e-73	38	303	2	272	Cellulase (glycosyl hydrolase family 5).
225344	BglC	3.40e-20	32	317	45	376	Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism].
395595	CBM_1	1.66e-15	445	473	1	29	Fungal cellulose binding domain.
197593	fCBD	1.04e-14	444	477	1	34	Fungal-type cellulose-binding domain. Small four-cysteine cellulose-binding domain of fungi

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AOY41714.1|CBM1|GH5_5	2.87e-276	1	477	1	477
ADX78145.1|CBM1|GH5_5|3.2.1.4	2.87e-276	1	477	1	477
UDD64503.1|CBM1|GH5_5	8.32e-206	1	477	1	490
QMW35398.1|CBM1|GH5_5	5.52e-204	1	477	1	490
QMW47460.1|CBM1|GH5_5	5.52e-204	1	477	1	490

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
1GZJ_A	1.68e-155	32	331	3	303	Structure of Thermoascus aurantiacus family 5 endoglucanase [Thermoascus aurantiacus],1GZJ_B Structure of Thermoascus aurantiacus family 5 endoglucanase [Thermoascus aurantiacus]
6T9F_A	2.40e-155	26	332	7	314	CRYSTAL STRUCTURE OF EN ENDOGLUCANASE S308P FROM PENICILLIUM VERRUCULOSUM [Talaromyces verruculosus],6T9F_B CRYSTAL STRUCTURE OF EN ENDOGLUCANASE S308P FROM PENICILLIUM VERRUCULOSUM [Talaromyces verruculosus],6T9F_C CRYSTAL STRUCTURE OF EN ENDOGLUCANASE S308P FROM PENICILLIUM VERRUCULOSUM [Talaromyces verruculosus],6T9F_D CRYSTAL STRUCTURE OF EN ENDOGLUCANASE S308P FROM PENICILLIUM VERRUCULOSUM [Talaromyces verruculosus]
5L9C_A	3.93e-154	26	332	7	314	Crystal structure of an endoglucanase from Penicillium verruculosum in complex with cellobiose [Talaromyces verruculosus],5L9C_B Crystal structure of an endoglucanase from Penicillium verruculosum in complex with cellobiose [Talaromyces verruculosus],5L9C_C Crystal structure of an endoglucanase from Penicillium verruculosum in complex with cellobiose [Talaromyces verruculosus],5L9C_D Crystal structure of an endoglucanase from Penicillium verruculosum in complex with cellobiose [Talaromyces verruculosus]
6TPC_A	3.93e-154	26	332	7	314	Chain A, Endoglucanase [Talaromyces verruculosus],6TPC_C Chain C, Endoglucanase [Talaromyces verruculosus]
1H1N_A	1.15e-153	32	331	4	304	Atomic resolution structure of the major endoglucanase from Thermoascus aurantiacus [Thermoascus aurantiacus],1H1N_B Atomic resolution structure of the major endoglucanase from Thermoascus aurantiacus [Thermoascus aurantiacus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q96WQ8|EGLB_ASPKW	7.14e-156	1	331	1	331	Probable endo-beta-1,4-glucanase B OS=Aspergillus kawachii (strain NBRC 4308) OX=1033177 GN=eglB PE=3 SV=1
sp|A1DME8|EGLB_NEOFI	2.99e-154	1	331	1	327	Probable endo-beta-1,4-glucanase B OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=eglB PE=3 SV=1
sp|B8MW97|EGLB_ASPFN	3.45e-154	10	331	9	331	probable endo-beta-1,4-glucanase B OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) OX=332952 GN=eglB PE=3 SV=1
sp|Q2UPQ4|EGLB_ASPOR	3.45e-154	10	331	9	331	Probable endo-beta-1,4-glucanase B OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=eglB PE=3 SV=1
sp|O74706|EGLB_ASPNG	3.00e-152	1	331	1	330	Endo-beta-1,4-glucanase B OS=Aspergillus niger OX=5061 GN=eglB PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000399	0.999553	CS pos: 28-29. Pr: 0.7744

TMHMM  Annotations     

There is no transmembrane helices in Afu2g09520-T-p1.