CAZyme Information: AYO43539.1

Basic Information

• Species: Malassezia restricta
• Lineage: Basidiomycota; Malasseziomycetes; ; Malasseziaceae; Malassezia; Malassezia restricta
• CAZyme ID: AYO43539.1
• CAZy Family: GT2
• CAZyme Description: GPI mannosyltransferase 2

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
371		40569.46	9.1975

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_MrestrictaCBS7877	4155	425264	59	4096

• Gene Location: location=CP033151:703992-705130(+)

Full Sequence      

MPPSTTRVLLASVLWRVVCVCLLLVSTHAQPAFDTSGELVRLTLRPGAWDAYWDAWAAPF
VRWDTVYFVAMAERGYVYEQMLAFQPGIVHVLRVMGSVPRVWGAPWSPTCAVLGGAIAAN
LASILAPVLLYRLLRTLTRSDAVAERAALLSVLAPASGTSLSAPTPEPFYSVLALSGLLL
LTHTHTAYQWGAAVCFALATWFRANGVLLCGFLVWHGLYKPVLESWPTRRTSHAISGIAS
ALVSVSPFVAQQWWAYTRLCPGRPWCDARLPLAYTFVQRAYWDVGFLRYWTVAQVPNFVL
AMPVLAVAAYACRPLVSSSVLVVLAPWRARQAPGDVYVYACHTLVLSRPDCAPDGDAGRH
ATRVVGMRGAV

Enzyme Prediction     

No EC number prediction in AYO43539.1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT76	9	320	5e-73	0.7641277641277642

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
282094	Mannosyl_trans2	6.39e-36	8	311	4	316	Mannosyltransferase (PIG-V). This is a family of eukaryotic ER membrane proteins that are involved in the synthesis of glycosylphosphatidylinositol (GPI), a glycolipid that anchors many proteins to the eukaryotic cell surface. Proteins in this family are involved in transferring the second mannose in the biosynthetic pathway of GPI.
227829	COG5542	5.76e-10	188	312	190	316	Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AYO43539.1|GT76	3.54e-276	1	371	1	371
AXA51352.1|GT76	3.62e-255	1	346	1	346
SHO79637.1|GT76	3.89e-109	4	335	8	343
CBQ69964.1|GT76	5.41e-74	7	346	44	409
SAM86026.1|GT76	2.19e-72	4	310	41	363

PDB Hits     

AYO43539.1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P0CP63|GPI18_CRYNB	1.81e-38	6	305	8	303	GPI mannosyltransferase 2 OS=Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) OX=283643 GN=GPI18 PE=3 SV=1
sp|P0CP62|GPI18_CRYNJ	1.81e-38	6	305	8	303	GPI mannosyltransferase 2 OS=Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) OX=214684 GN=GPI18 PE=3 SV=1
sp|Q2GSI6|GPI18_CHAGB	3.31e-33	15	359	29	393	GPI mannosyltransferase 2 OS=Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) OX=306901 GN=GPI18 PE=3 SV=1
sp|Q5KR61|PIGV_RAT	1.16e-26	47	348	50	360	GPI mannosyltransferase 2 OS=Rattus norvegicus OX=10116 GN=Pigv PE=2 SV=1
sp|Q4WQ21|GPI18_ASPFU	7.96e-25	60	306	84	323	GPI mannosyltransferase 2 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=gpi18 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.010845	0.989112	CS pos: 29-30. Pr: 0.9639

TMHMM  Annotations     

Start	End
7	29
112	134
193	215
290	312