CAZyme Information: ATY59918.1

Basic Information

• Species: Cordyceps militaris
• Lineage: Ascomycota; Sordariomycetes; ; Cordycipitaceae; Cordyceps; Cordyceps militaris
• CAZyme ID: ATY59918.1
• CAZy Family: AA7
• CAZyme Description: RNA-directed RNA polymerase (Sad-1)

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1877	CP023323|CGC14	210193.91	6.6558

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_CmilitarisATCC34164	9362	N/A	75	9287

• Gene Location: location=CP023323:1342815-1349199(-)

Full Sequence      

MLRSLCKSRFRGRRFAVPSRQCQSTTTHSAKSASSWSSGALIGIATATGAIGWSVAQWQT
EKISSQVHSGIPSAAIKEIVSELGNEEIISTDDEDLKRHGYSEWSTVNPDTLPVAVAYPR
STEDVAAIARICHTYRVPLIAFSGGTSLEGNFSAPYGGISVDFAHMDRILQLNKDDMDVV
VQPSIGWQDLNQALADRGAGLFFPVDPGPTAKIGGMIGTNCSGTNAVRYGTMKDWVINLT
VVLADGRIIKTRRRPRKSSAGYNLNGLFVGSEGTLGIVTEATLKLAVIPDAYSVGVVSFP
TIRAAAAAAAGVMRAGVPVACMEIMDDVQMRVVNLSGHTAPRTWKELPTLFFKFSGSKAS
VAENISTVQAITSENGGEEFEFAKDEREQKLLWSARKESLWSMLALRKADEDVWSTDVAV
PLSRLADLIEVSKKEMDDLGMFASILGHIGDGNFHESILYNRNDPEERARVARCVHNMVH
RALNMEGTCTGEHSIGWGKKASLVAELGQETVDVMATIKHALDPRWVLNPGKIMDVPWLP
RETYLDSADVVVTPIRRLVKEPWFLSDLLHTTSLNQMTTYYQYPEQLAEKWSNAELSEDR
SRSASRNPRDDDDVPPQPSLERSFISLKLSNMPKDITIQKIYKAFSPKGCIQSLEIFDAR
PLELMAVGRIDFAPPPKIEFWKNGRFELQLDEQEKPVTISVALNEVRHGAPKSAADQRYP
DIISMQLKSLDFGTLGKDTMVIGATIETTEPGDLSLEFNNRKGEVVMYFQFEERQRRTSR
KRQYKLITNVSAISKAPDILDLMPPDSKRWHCNDSWVRATDIYEVLSEPLLLPISTYSRS
KLGKCIDISRLKTFRCTIDEAKAQSLTAVEHFMMALDQYNIDPTRTTLKLERDQKCMWDI
LDHQTTGSSNALEYLGLTANCIYLDFAVRYRLEVCVSRGYLREYALDAVFLEKLASLDVA
KASRMLDYIADQELQVEDPMQIFENAEFLCAPAKKRIPHYCSLVLKVNITPTCLKVNSPN
VESSNRVMRKYNNLHDRFLRVQFLSETESDRIAKDRYNNDDVWKRLLRALHKGIRIGDRT
YEFLAFGNSQLREGSVTFFCPTAHLSCDDIRKWLGNFDHIRNIAKFGARLGQCFSTTREV
RGIRVPTVRLIDDIETEGECFSDGVGIISGLLGKLVVDEMKLDVVGEPSAFQFRMGGAKG
VLAVWPREYAKHMEVCVRKSQIKFTTEANTLEIVKCAKTTTATLNRQTIIILEHLGVSCG
AFLELLNTHIKQYEEAMTDRTAAIDLLTKFVDENQTTVIIAELLKADFQDPFVKNLLKLW
RSWSLKLMKEKCRIHVEKSAFVMGCVDETGTLQGHSKKTEGSNTKRMDDLPQIFLQISNR
KYRNKTTIIKGLCLIGRNPSLHAGDIRVVQAVDMPCLRHLKDVVVFPSKGDRSLPSMLSG
GDLDGDDYFVIWEPTLMPKVWNTPPMHSEPVNPQNLDRDVEVNDLRNFVVKYMKNDFLGL
IAYSHLAHADKKGAVDYPKTGIPAEWTRAKYQPKEWPHFMQPKSRTYHSRRALGKLYDRV
ADENFDYVPSCEDEFDSRVSQGIHLTDDILAIARDIKTEYDQAARRLLKQFRLATEFELY
SGWAMSKPAVGSDYKRQEDLGQQFGALKQRFRDMCIQAAGEAGGGQLEVLVAAMYKVTQN
EVKCFLAAAEGGNLTYSSKPMPLIGFPWIFHWVLVKIAMGRDYKPLETSLAAAVRPTPMA
PARKTDDDAPRVVDAPTEPRMSIEEPKSAGKVKEQANLLDFGAADVDAKPATTPYETPDE
TAESVALSRGAKGHEMVARESDSGAQSLGSLEPCRERSPGVPHTVPSPPISGHLEYRESG
MDRLLRLYEDSEDSEED

Enzyme Prediction     

No EC number prediction in ATY59918.1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA4	66	300	4.8e-23	0.45977011494252873

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
398723	RdRP	0.0	1017	1560	2	554	RNA dependent RNA polymerase. This family of proteins are eukaryotic RNA dependent RNA polymerases. These proteins are involved in post transcriptional gene silencing where they are thought to amplify dsRNA templates.
178402	PLN02805	6.70e-142	60	534	83	549	D-lactate dehydrogenase [cytochrome]
223354	GlcD	1.40e-105	75	533	1	455	FAD/FMN-containing dehydrogenase [Energy production and conversion].
273050	glcD	7.03e-89	116	532	1	413	glycolate oxidase, subunit GlcD. This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity. [Energy metabolism, Other]
397178	FAD-oxidase_C	1.87e-56	288	533	1	248	FAD linked oxidases, C-terminal domain. This domain has a ferredoxin-like fold.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSZ31245.1|GT31	1.25e-164	102	490	537	905
QGA13141.1|AA4	6.62e-12	74	303	46	283
VBB76857.1|AA4	3.77e-11	75	532	69	577
BCS27721.1|AA4	6.00e-11	112	303	85	283
UPK89995.1|AA4	1.36e-10	115	532	73	543

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7EU0_M	1.07e-88	1009	1717	386	1113	Chain M, RNA-dependent RNA polymerase 2 [Arabidopsis thaliana],7EU1_M Chain M, RNA-dependent RNA polymerase 2 [Arabidopsis thaliana]
7ROZ_A	1.76e-88	1009	1717	386	1113	Chain A, RNA-dependent RNA polymerase 2 [Arabidopsis thaliana],7RQS_A Chain A, RNA-dependent RNA polymerase 2 [Arabidopsis thaliana]
6LPN_A	2.06e-38	119	534	60	471	Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPN_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPP_A Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPP_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPQ_A Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPQ_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPT_A Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPT_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPU_A Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPU_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPX_A Chain A, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens],6LPX_B Chain B, D-2-hydroxyglutarate dehydrogenase, mitochondrial [Homo sapiens]
3PM9_A	1.31e-35	116	534	55	476	Chain A, Putative oxidoreductase [Rhodopseudomonas palustris],3PM9_B Chain B, Putative oxidoreductase [Rhodopseudomonas palustris],3PM9_C Chain C, Putative oxidoreductase [Rhodopseudomonas palustris],3PM9_D Chain D, Putative oxidoreductase [Rhodopseudomonas palustris],3PM9_E Chain E, Putative oxidoreductase [Rhodopseudomonas palustris],3PM9_F Chain F, Putative oxidoreductase [Rhodopseudomonas palustris]
2UUU_A	1.24e-23	113	534	138	584	alkyldihydroxyacetonephosphate synthase in P212121 [Dictyostelium discoideum],2UUU_B alkyldihydroxyacetonephosphate synthase in P212121 [Dictyostelium discoideum],2UUU_C alkyldihydroxyacetonephosphate synthase in P212121 [Dictyostelium discoideum],2UUU_D alkyldihydroxyacetonephosphate synthase in P212121 [Dictyostelium discoideum],2UUV_A alkyldihydroxyacetonephosphate synthase in P1 [Dictyostelium discoideum],2UUV_B alkyldihydroxyacetonephosphate synthase in P1 [Dictyostelium discoideum],2UUV_C alkyldihydroxyacetonephosphate synthase in P1 [Dictyostelium discoideum],2UUV_D alkyldihydroxyacetonephosphate synthase in P1 [Dictyostelium discoideum]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|O14227|RDP1_SCHPO	1.66e-135	583	1710	29	1197	RNA-dependent RNA polymerase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rdp1 PE=1 SV=1
sp|Q12627|DLD1_KLULA	3.89e-131	76	536	107	569	D-lactate dehydrogenase [cytochrome], mitochondrial OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=DLD1 PE=3 SV=2
sp|P32891|DLD1_YEAST	9.67e-123	76	533	111	574	D-lactate dehydrogenase [cytochrome] 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DLD1 PE=1 SV=2
sp|Q94AX4|DLD_ARATH	1.85e-122	60	534	95	561	D-lactate dehydrogenase [cytochrome], mitochondrial OS=Arabidopsis thaliana OX=3702 GN=DLD PE=1 SV=1
sp|F1QXM5|LDHD_DANRE	2.31e-115	73	536	29	490	Probable D-lactate dehydrogenase, mitochondrial OS=Danio rerio OX=7955 GN=ldhd PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
0.999460	0.000545

TMHMM  Annotations     

There is no transmembrane helices in ATY59918.1.