CAZyme Information: ATEG_06948-t26_1-p1

Basic Information

• Species: Aspergillus terreus
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus terreus
• CAZyme ID: ATEG_06948-t26_1-p1
• CAZy Family: GH43
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1533	CH476603|CGC5	171278.83	4.9202

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AterreusNIH2624	10551	341663	150	10401

• Gene Location: location=CH476603:292049-297072(+)

Full Sequence      

MATVARSSYFNVHPKLYLASRGKRYLRQIVTTFATVFSLVCFHYHYLFISGPQRTTDMVF
PLRSIASWRVGVVVAAALASLVHASPSVNVALQASFDSAPYLIELLETVAEENSTAYFPL
LDRVADGAFDDAVTDKEVYDRFLQVVREGGHLKTPETLSSFKLSLAIRSATPRIAAHYQY
YNASVQHSLMAAQDAACPVWVHSEGKQYCSSTMERAQQDVLGELDPKELPFDRVLGDPSL
PPAVLYADVTSPMFRDFHHTLTSLAKEGQVSYRVRYRPPQHPIPRPLFVSGYGVELALKR
TDYIVIDDRDAEGRGSDSAESTKPGTVDEEAPDDLRPLSSSEVSRLGVNTVSYVMDSENP
LDTLVKLSQDFPKYSSKVAAHNASASLLKDIRFSRLQMLPSGANVMWINGVQVNPRQIDA
FSLSDHLRRERRLIEKFRNLGLSAQEAVDLLSHEYIAEAMAQDAAQRYNYRDEIEGGNVI
IWLNDLEKDAKYEGWPSDLTAFLQRTYPGQLPPVRRDAHNIVVPVDLTNAEDMNLVVQTI
QVFVKKKIPVRFGLVPTGSSPGSMAQLKVAHYLQRTYGLSSLIQYLEESAAKNKFASPDK
GSFQAAIKDRNVRADKQPLSFEEVLKDDELGSFVSRTLDYQNRLGINGETSPLFVNGVPI
SRGENWVQEMSIRVNKDLQLIQQSIFEGLLEESTWIPGFFLSGAFDRRNPWVIPEDPKDI
KVVDLAGVAGSRQQSLDALPRIPSDGEDALESAYLVVVGDFDAESGLKLLKATLGSRKEH
GEAEMLFLHNPATDTPTSGRSATLYRLLKDGKETDVEKLLSAFSSDSATTNEAEEIVAFW
EAQQPLAYDLGFKPGQSGFIVNGRVIGPMQDDSVVMPEDIGALLGYEQAKRIGPVAKAAR
ALGFGSKVAEPLAFAKLTSLATLSTISDVPEGIFESIWSDSDSVITVSNSEDAAITIVAS
IDPTSEVAQRWLPILNVLSQLASVRLRLFLNPREEISELPTKRFYRYVLDLEPSFNDDGS
LARPGASFSGVPVEALLTLGMDVPSPWLVAPKESIHDLDNIKLSSLKEGSNVDAIYALEH
ILIEGHSRDLTTQSPPRGVQLVLGTEDHPYFADTIIMANLGYFQFKAQPGLWKINLKPGR
SERIFNLDSVGGLGYSPQPGDENNEVALLSFQGKTLFPRLSRKKGFEDEDVLETGPRPGS
PMDFVSKGLNFASGVLSSVGVGSKAVSEKQADINIFSVASGHLYERMLNIMMVSVMRNTK
HTVKFWFIEQFLSPSFKEFLPHLAKEYGFSYEMVTYKWPHWLRAQREKQREIWGYKILFL
DVLFPLSLDKVIFVDADQIVRTDMYDLVSLDLEGAPYGFTPMCDSREEMEGFRFWKQGYW
KTFLRGQPYHISALYVVDLSRFRALAAGDRLRGQYQMLSADPNSLSNLDQDLPNHMQHHI
PIKSLPQEWLWCETWCSDESLGQARTIDLCNNPQTKEPKLDRARRQVPEWTAYDDEIAAL
AKRVAQDKEQEEDIPVPEEEDDEAPSTWDKDEL

Enzyme Prediction     

EC	2.4.1.-:29

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT24	1233	1480	3.9e-135	0.9959677419354839

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
133054	GT8_HUGT1_C_like	0.0	1233	1480	1	248	The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity.
408203	Glyco_transf_24	0.0	1233	1500	1	268	Glucosyltransferase 24. This is the catalytic domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT). This domain belongs to glucosyltransferase 24 family (GT24) A-type domain. The GT domain displays the expected glycosyltransferase type A (GT-A) fold.
408201	Thioredoxin_14	1.90e-99	468	712	1	248	Thioredoxin-like domain. This is the third out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
399437	UDP-g_GGTase	2.45e-63	1084	1193	1	109	UDP-glucose:Glycoprotein Glucosyltransferase. UDP-g_GGTase is an important, central component of the QC system in the ER for checking that glycoproteins are folded correctly. This QC prevents incorrectly folded glycoproteins from leaving the ER.
408199	Thioredoxin_12	1.21e-62	98	282	1	182	Thioredoxin-like domain. This is one of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
UDD64319.1|GT24	0.0	58	1533	1	1487
QRD91624.1|GT24	0.0	58	1533	1	1487
QMW47293.1|GT24	0.0	58	1533	1	1487
QMW35231.1|GT24	0.0	58	1533	1	1487
BAE65008.1|GT24|2.4.1.-	0.0	58	1533	1	1487

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5MU1_A	0.0	82	1508	5	1455	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5MZO_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TRF_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
5NV4_A	0.0	82	1508	5	1455	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
5Y7O_A	0.0	87	1199	5	1130	Crystal structure of folding sensor region of UGGT from Thermomyces dupontii [Thermomyces dupontii],5Y7O_B Crystal structure of folding sensor region of UGGT from Thermomyces dupontii [Thermomyces dupontii]
6TRT_A	0.0	82	1508	5	1455	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS2_A	0.0	82	1508	5	1221	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_C Chain C, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_D Chain D, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q09140|UGGG_SCHPO	3.80e-284	76	1511	10	1435	UDP-glucose:glycoprotein glucosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=gpt1 PE=1 SV=2
sp|Q6P5E4|UGGG1_MOUSE	6.16e-248	85	1500	44	1523	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Mus musculus OX=10090 GN=Uggt1 PE=1 SV=4
sp|Q9NYU2|UGGG1_HUMAN	3.94e-246	85	1509	44	1532	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3
sp|Q9JLA3|UGGG1_RAT	2.05e-244	68	1500	23	1523	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Uggt1 PE=1 SV=2
sp|Q09332|UGGG_DROME	9.26e-234	92	1504	34	1511	UDP-glucose:glycoprotein glucosyltransferase OS=Drosophila melanogaster OX=7227 GN=Uggt PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000023	0.000008

TMHMM  Annotations     

Start	End
29	51