CAZyme Information: ATEG_00658-t26_1-p1

Basic Information

• Species: Aspergillus terreus
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus terreus
• CAZyme ID: ATEG_00658-t26_1-p1
• CAZy Family: AA3
• CAZyme Description: mannosyl-oligosaccharide alpha-1,2-mannosidase precursor

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
508		56288.64	4.9914

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AterreusNIH2624	10551	341663	150	10401

• Gene Location: location=CH476594:1848549-1850174(-)

Full Sequence      

MHLPSLSLPLAALTLATPSLAYPYYRTEQPLQNNLAQSRANTIKEAFSHAWDGYKKYAYP
HDELHPVSNGYGDSRNGWGASAVDALSTAIIMRNATIVNQILDHIAQVDYSKTNDTVSLF
ETTIRYLGGMLSGYDLLKGPASGLVRDSKKVDMLLTQSKKLADVLKFAFDTPSGVPYNNI
NINTHGNDGATSNGLAVTGTLVLEWTRLSDLTGDDEYAKLSQKAQSYLLKPQPASSEPFP
GLVGSHISIETGEFTDAQVSWNGGDDSFYEYLIKMYVYDPEAFGEYKDRWEAAAQSSMEH
LASHPSTRPDLTFLASYNDGKLGLSSQHLTCFDGGSFLLGGTVLDNDDYIKFGLDLVKGC
HETYNATLTGIGPESFAWDPNSVPSNQKALYEKAGFYIQSGAYILRPEVIESFYYAYRIT
GEEQYREWIWNAFVAINKYCRTSSGFAGLQDVNAANGGGRYDNQESFLFAEVMKYVYLAH
SGDAEWQVQRGNGNKFVFNTEAHPFRVR

Enzyme Prediction     

EC	3.2.1.113:12

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH47	46	507	1.9e-142	0.9977578475336323

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
396217	Glyco_hydro_47	0.0	46	507	1	453	Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2).
240427	PTZ00470	1.26e-123	35	507	68	518	glycoside hydrolase family 47 protein; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BAE57653.1|GH47|3.2.1.113	8.74e-308	1	507	1	508
BAC07247.1|GH47|3.2.1.113	8.74e-308	1	507	1	508
QRD82359.1|GH47	8.74e-308	1	507	1	508
QMW39988.1|GH47	8.74e-308	1	507	1	508
QMW27917.1|GH47	8.74e-308	1	507	1	508

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
1KKT_A	1.67e-276	1	507	1	508	Structure of P. citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the ER and Golgi Class I enzymes [Penicillium citrinum],1KKT_B Structure of P. citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the ER and Golgi Class I enzymes [Penicillium citrinum],1KRE_A Structure Of P. Citrinum Alpha 1,2-Mannosidase Reveals The Basis For Differences In Specificity Of The Er And Golgi Class I Enzymes [Penicillium citrinum],1KRE_B Structure Of P. Citrinum Alpha 1,2-Mannosidase Reveals The Basis For Differences In Specificity Of The Er And Golgi Class I Enzymes [Penicillium citrinum],1KRF_A Structure Of P. Citrinum Alpha 1,2-mannosidase Reveals The Basis For Differences In Specificity Of The Er And Golgi Class I Enzymes [Penicillium citrinum],1KRF_B Structure Of P. Citrinum Alpha 1,2-mannosidase Reveals The Basis For Differences In Specificity Of The Er And Golgi Class I Enzymes [Penicillium citrinum]
2RI8_A	6.58e-272	37	507	3	473	Penicillium citrinum alpha-1,2-mannosidase complex with glycerol [Penicillium citrinum],2RI8_B Penicillium citrinum alpha-1,2-mannosidase complex with glycerol [Penicillium citrinum],2RI9_A Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog [Penicillium citrinum],2RI9_B Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog [Penicillium citrinum]
1HCU_A	2.28e-173	38	508	14	493	Chain A, ALPHA-1,2-MANNOSIDASE [Trichoderma reesei],1HCU_B Chain B, ALPHA-1,2-MANNOSIDASE [Trichoderma reesei],1HCU_C Chain C, ALPHA-1,2-MANNOSIDASE [Trichoderma reesei],1HCU_D Chain D, ALPHA-1,2-MANNOSIDASE [Trichoderma reesei]
5KKB_A	1.29e-73	29	507	13	467	Structure of mouse Golgi alpha-1,2-mannosidase IA and Man9GlcNAc2-PA complex [Mus musculus],5KKB_B Structure of mouse Golgi alpha-1,2-mannosidase IA and Man9GlcNAc2-PA complex [Mus musculus]
1NXC_A	1.62e-73	29	507	11	465	Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases) [Mus musculus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q0D076|MNS1B_ASPTN	0.0	1	508	1	508	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=mns1B PE=3 SV=1
sp|Q2ULB2|MNS1B_ASPOR	1.55e-308	1	507	1	508	Mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=mns1B PE=1 SV=1
sp|B8N417|MNS1B_ASPFN	1.55e-308	1	507	1	508	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) OX=332952 GN=mns1B PE=3 SV=2
sp|Q12563|MNS1B_ASPPH	8.22e-307	1	507	1	510	Mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Aspergillus phoenicis OX=5063 GN=mns1B PE=2 SV=1
sp|A2QAS2|MNS1B_ASPNC	5.52e-305	1	507	1	510	Probable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=mns1B PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000257	0.999711	CS pos: 21-22. Pr: 0.9825

TMHMM  Annotations     

There is no transmembrane helices in ATEG_00658-t26_1-p1.