CAZyme Information: ASPVEDRAFT_84794-t33_1-p1

Basic Information

• Species: Aspergillus versicolor
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus versicolor
• CAZyme ID: ASPVEDRAFT_84794-t33_1-p1
• CAZy Family: GT31
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1481		164739.06	4.6817

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AversicolorCBS583.65	13364	1036611	142	13222

• Gene Location: location=KV878130:905370-910057(+)

Full Sequence      

MRLSSGIAASWRLSCIAFATLLVSSVTASPSVNVALQASFDSGPYLIELLETAAEENPAS
YFPLLDRIADGAFDDSVSDKEVYDRFLQVVVEDGHLATPESLSSFKLSLSIRSASPRVAA
HYQFYNTSVQHLLMAAQDAACPVWVHSDGKQYCSSTMERAQQDVYGEADGRELPFDRVFG
DNSLPPAILYADVASPMFKDFHHTLSSMAKEGEVSYRVRYRPPQHWSSRPLFVSGYGVEL
ALKRTDYIVIDDRDAEQRDSNSKNAKSAESEESPDDLRPLSSSEVARLGLNTAQYVADSK
DPLDTLVKLSQDFPKYSSIIAAHNRSDKLLREIKTNRLEMLPSGANALWINGVQIDPRQI
DAFFLVDHLRRERKLMESFRSLGLTAKEAVDLLSHDSVTESVVQDVSQRYDYRDEIEGGG
VVIWLNDLEKDARYESWPGDLVLFLRRTYPGQLPAVSRDLNNIVFPLDLSNVEDVDLIVT
TIQLFVKKKIPVRFGVVPLASSAGSTAQLKVAHYLQETFGLSSLMTYLEEASKKNKLATP
DKDSFLAATEDKTPRAEKEALSLDEVLSNQDVALSVSHTTAYQDRLGIKPETPLVFINGI
PIVRGESWPQEMSAKVEQDLRLIQRSIVDGLFDEDTWLPGFFLSQAFTRRVPWIVPEDSK
DVELVDLTKIAVQSGDLIGQVPRVASQDEPLESVHMIVVGDFGTKAGLKTLVSALGMQEK
EAKAEMLLIHNPEDPSASDTASALIYHSLKGGNDVDVARILADITSPESSDADAQAAVDF
WSKFQPLAETLGFSPGTTGVVVNGRVVKPTQDVTTEDLKQLLAYENNTRIGPVAKAAKDL
PFASKLSDPFSVAKLTSLVALSTVSDVPEGLFEAASDVRAKFFNDWSGSGSIITIPGPED
PTITIAASIDPTSETSQRWLPILKALSELDGVRLNLFMNPRDENRELPIKRFYRYVLSPE
PSFGDDGSVQRPGATFSGVPVEALLTLGMDVPPYWLVAPQDSVHDLDNIKLSSVKEGSNV
DAVYALEHILIEGHSRDMTTKSPPRGVQLVLGTEDNPYFADTIVMANLGYFQFKAQPGLW
SINLKPGRSEKIFNLDSLGQLGYSPQAGDDSKEVALLSFQGKTLFPRMSRRKGQEDEDVL
ESGPKPGSAMDFMSKGFNFASNVLSSVGVGSKNNAEANADINIFSVASGHLYERMLNIMM
ISVMRNTDKTVKFWFIEQFLSPSFKSFLPHLAAEYGFKYEMVTYKWPHWLRAQKEKQREI
WGYKILFLDVLFPLSLDKVIFVDADQIVRTDMSDLVNFDLEGAPYGFTPMCDSRTEMEGF
RFWKQGYWKSFLRGSPYHISALYVVDLVQFRAMAAGDRLRGQYQMLSADKNSLSNLDQDL
PNHMQHHIPIKSLPQEWLWCETWCSDEALGQARTIDLCNNPQTKEPKLERAKRQVPEWTV
YDEEIAGLAKRVADADTARVEEVGADEAEHEDTASWKKDEL

Enzyme Prediction     

EC	2.4.1.-:29

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT24	1181	1428	3.1e-133	0.9959677419354839

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
408203	Glyco_transf_24	0.0	1181	1448	1	268	Glucosyltransferase 24. This is the catalytic domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT). This domain belongs to glucosyltransferase 24 family (GT24) A-type domain. The GT domain displays the expected glycosyltransferase type A (GT-A) fold.
133054	GT8_HUGT1_C_like	0.0	1181	1428	1	248	The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity.
408201	Thioredoxin_14	2.09e-89	410	654	1	248	Thioredoxin-like domain. This is the third out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
399437	UDP-g_GGTase	1.78e-62	1032	1141	1	109	UDP-glucose:Glycoprotein Glucosyltransferase. UDP-g_GGTase is an important, central component of the QC system in the ER for checking that glycoproteins are folded correctly. This QC prevents incorrectly folded glycoproteins from leaving the ER.
408200	Thioredoxin_13	1.33e-60	272	406	1	135	Thioredoxin-like domain. This is the second out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCS29321.1|GT24	0.0	1	1481	1	1482
EAA60425.1|GT24	0.0	1	1481	1	1483
BAE65008.1|GT24|2.4.1.-	0.0	6	1481	6	1487
QRD91624.1|GT24	0.0	6	1481	6	1487
QMW47293.1|GT24	0.0	6	1481	6	1487

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5MU1_A	0.0	26	1452	5	1451	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5MZO_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],5N2J_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TRF_A Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
5NV4_A	0.0	26	1452	5	1451	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
5Y7O_A	0.0	31	1147	5	1130	Crystal structure of folding sensor region of UGGT from Thermomyces dupontii [Thermomyces dupontii],5Y7O_B Crystal structure of folding sensor region of UGGT from Thermomyces dupontii [Thermomyces dupontii]
6TRT_A	0.0	26	1452	5	1451	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]
6TS2_A	0.0	26	1452	5	1217	Chain A, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_B Chain B, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_C Chain C, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495],6TS2_D Chain D, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein [Thermochaetoides thermophila DSM 1495]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q09140|UGGG_SCHPO	9.37e-280	17	1462	8	1438	UDP-glucose:glycoprotein glucosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=gpt1 PE=1 SV=2
sp|Q6P5E4|UGGG1_MOUSE	9.14e-241	29	1448	44	1523	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Mus musculus OX=10090 GN=Uggt1 PE=1 SV=4
sp|Q9JLA3|UGGG1_RAT	1.45e-238	29	1448	44	1523	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Uggt1 PE=1 SV=2
sp|Q9NYU2|UGGG1_HUMAN	2.38e-237	22	1451	36	1526	UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3
sp|Q09332|UGGG_DROME	8.64e-235	36	1454	34	1513	UDP-glucose:glycoprotein glucosyltransferase OS=Drosophila melanogaster OX=7227 GN=Uggt PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000238	0.999731	CS pos: 28-29. Pr: 0.9785

TMHMM  Annotations     

There is no transmembrane helices in ASPVEDRAFT_84794-t33_1-p1.