CAZyme Information: ASPBRDRAFT_36219-t33_1-p1

Basic Information

• Species: Aspergillus brasiliensis
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus brasiliensis
• CAZyme ID: ASPBRDRAFT_36219-t33_1-p1
• CAZy Family: GH32
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
458	KV878679|CGC6	48873.80	6.4972

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AbrasiliensisCBS101740	13263	767769	274	12989

• Gene Location: location=KV878679:772548-773974(-)

Full Sequence      

MKWLTLLPIALGLAHASIIAFSPPTNPDIIYSLTIPNTTTLSSPGPIYIQITAPTSIQWV
GLGQGAQMTGSNMFLLYTSSSTKITLSPRSGLGHFEPQYTSSTQITMLPGTGISINPDNS
SSSARTTMTANFRCDNCLTWQDGTGRMDPASTNFPFIWAYRAGVPINSASMDADLTIHDD
MGSMQVDLTRAAMPSTTDDDDSNQTNPFARYNPATDSIPAQESPNTPTGNTPPISLPNLT
KMTHILISHATLMSLSFVLFYPLSALIMPLPISLPISKYNLHMPLQLFTLVMTLAGFACG
IYLAYETGQLRTAHPVLGIIVVGVLVLFQPGMGWLQHRGYLRTGGRTVWGVAHQWVGRGV
IVVGVVNGGVGIHVARKMGMAPVGAVVGYAVVAGVVGGVYLGGLLLGRVVERRRKNGVDE
REGERGEGNEGDEGRVDSVQGRENGDGEKGGSVEERDG

Enzyme Prediction     

No EC number prediction in ASPBRDRAFT_36219-t33_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
AA8	27	193	2.9e-21	0.8736263736263736

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
187688	CDH_like_cytochrome	1.18e-50	16	188	9	168	Heme-binding cytochrome domain of fungal cellobiose dehydrogenases. Cellobiose dehydrogenase (CellobioseDH or CDH) is an extracellular fungal oxidoreductase that degrades both lignin and cellulose. Specifically, CDHs oxidize cellobiose, cellodextrins, and lactose to corresponding lactones, utilizing a variety of electron acceptors. Class-II CDHs are monomeric hemoflavoenzymes that are comprised of a b-type cytochrome domain linked to a large flavodehydrogenase domain. The cytochrome domain of CDH and related enzymes, which this model describes, folds as a beta sandwich and complexes a heme molecule. It is found at the N-terminus of this family of enzymes, and belongs to the DOMON domain superfamily, a ligand-interacting motif found in all three kingdoms of life.
406418	CDH-cyt	8.88e-31	28	195	19	177	Cytochrome domain of cellobiose dehydrogenase. CDH-cyt is the cytochrome domain, at the N-terminus, of cellobiose dehydrogenase. CDH-cyt folds as a beta sandwich with the topology of the antibody Fab V(H) domain and binds iron. The haem iron is ligated by Met83 and His181 in UniProtKB:Q01738.
176490	Cyt_b561_FRRS1_like	8.71e-22	244	355	34	143	Eukaryotic cytochrome b(561), including the FRRS1 gene product. Cytochrome b(561), as found in eukaryotes, similar to and including the human FRRS1 gene product (ferric-chelate reductase 1), also called SDR-2 (stromal cell-derived receptor 2). This family comprises a variety of domain architectures, many of which contain dopamine beta-monooxygenase (DOMON) domains. The protein might act as a ferric-chelate reductase, catalyzing the reduction of Fe(3+) to Fe(2+), such as associated with the transport of iron from the endosome to the cytoplasm. It is assumed that this protein uses ascorbate as the electron donor. Belongs to the cytochrome b(561) family, which are secretory vesicle-specific electron transport proteins. Cytochromes b(561) are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments.
214769	B561	8.27e-08	249	355	2	112	Cytochrome b-561 / ferric reductase transmembrane domain. Cytochrome b-561 recycles ascorbate for the generation of norepinephrine by dopamine-beta-hydroxylase in the chromaffin vesicles of the adrenal gland. It is a transmembrane heme protein with the two heme groups being bound to conserved histidine residues. A cytochrome b-561 homologue, termed Dcytb, is an iron-regulated ferric reductase in the duodenal mucosa. Other homologues of these are also likely to be ferric reductases. SDR2 is proposed to be important in regulating the metabolism of iron in the onset of neurodegenerative disorders.
176489	Cyt_b561	3.48e-05	245	332	1	100	Eukaryotic cytochrome b(561). Cytochrome b(561) is a family of endosomal or secretory vesicle-specific electron transport proteins. They are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments. This is an exclusively eukaryotic family. Members of the prokaryotic cytochrome b561 family are not deemed homologous.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CAE7013938.1|AA8	8.02e-54	9	418	12	388
SMR55355.1|AA0	4.24e-48	29	416	25	367
SMR57731.1|AA0	4.24e-48	29	416	25	367
SMR42136.1|AA0	1.42e-46	1	420	1	394
SMR44317.1|AA0	1.42e-46	1	420	1	394

PDB Hits     

ASPBRDRAFT_36219-t33_1-p1 has no PDB hit.

Swiss-Prot Hits     

ASPBRDRAFT_36219-t33_1-p1 has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000227	0.999750	CS pos: 16-17. Pr: 0.9610

TMHMM  Annotations     

Start	End
252	274
287	306
316	335
356	375
385	407