CAZyme Information: AN0104-T-p1

Basic Information

• Species: Aspergillus nidulans
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus nidulans
• CAZyme ID: AN0104-T-p1
• CAZy Family: AA1
• CAZyme Description: Ortholog(s) have role in protein N-linked glycosylation and endoplasmic reticulum localization

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
413	ChrVIII_A_nidulans_FGSC_A4|CGC22	46395.14	9.5648

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AnidulansFGSCA4	10988	227321	276	10712

• Gene Location: location=ChrVIII_A_nidulans_FGSC_A4:4600678-4602038(-)

Full Sequence      

MALTDLVSGLCSNPKHTKWIAPILNIADGLLCAFIIWKVPYTEIDWTTYMQQVKLYLSGE
RDYTLIKGSTGPLVYPAAHVYSYSLFHHLTDEGRDIVFGQIIFAFLYLICLTVVMACYRR
VGAPPYLFPLLVLSKRLHSVYMLRLFNDGLAALAMWGSIWLFINRKWTPAVVLWSLGLGV
KMTLILLVPAVMVVLALSLDIGRCIRLAGLALGIQILLAIPFLKTNPSGYFERAFEFGRQ
FMFKWTVNWRFVGEDIFLSKGFWAGLIVLHLLILVVLGFTCFLNPSGTSLPDFAGRFLTG
QHRGIALHPSFIMSALLTSLSVGLLCARSLHYQFFAYLSWATPFLLWQAGYHPILVYALW
LVQEWAWNVYPSTNLSSAAVVLLLGAQVLGVLVNRDRAFPSSPPTPKAKQHVQ

Enzyme Prediction     

EC	2.4.1.258:10

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT58	22	377	6.9e-139	0.9945054945054945

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
398745	ALG3	0.0	22	377	1	358	ALG3 protein. The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl pyrophosphate. Whereas early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9GlcNAc2-PP-Dol on the lumenal side use Dol-P-Man. ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CBF90192.1|GT58	3.76e-306	1	413	1	413
BCS19227.1|GT58	1.45e-236	1	413	1	439
BCR98022.1|GT58	2.13e-199	6	413	6	413
BCS10476.1|GT58	2.13e-199	6	413	6	413
BAE62911.1|GT58	3.02e-199	1	413	1	413

PDB Hits     

AN0104-T-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q2U6A4|ALG3_ASPOR	5.37e-200	1	413	1	413	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=alg3 PE=3 SV=1
sp|Q4WVG2|ALG3_ASPFU	3.91e-187	1	394	9	402	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=alg3 PE=3 SV=1
sp|A1DDZ3|ALG3_NEOFI	2.34e-179	1	394	1	394	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=alg3 PE=3 SV=1
sp|A1CBE6|ALG3_ASPCL	3.98e-178	1	413	63	472	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=alg3 PE=3 SV=1
sp|A2RA94|ALG3_ASPNC	9.08e-174	6	413	6	409	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=alg3 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000029	0.000002

TMHMM  Annotations     

Start	End
20	42
96	118
141	163
172	194
204	223
261	283
305	327
334	356
371	393