dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: AMAG_13103-t26_1-p1

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Basic Information help

Species

Allomyces macrogynus

Lineage

Blastocladiomycota; Blastocladiomycetes; ; Blastocladiaceae; Allomyces; Allomyces macrogynus

CAZyme ID

AMAG_13103-t26_1-p1

CAZy Family

GT2

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
262	GG745356\|CGC1	27684.19	9.8968

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AmacrogynusATCC38327	19333	578462	535	18798

Gene Location

Full Sequence Download help

Enzyme Prediction help

EC	3.2.1.14:41	3.2.1.-:2	3.2.1.17:2	3.2.1.132:1

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH18	1	159	2.8e-33	0.4527027027027027

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
214753	Glyco_18	1.75e-42	1	153	182	334	Glyco_18 domain.
225862	ChiA	1.77e-37	1	167	249	436	Chitinase, GH18 family [Carbohydrate transport and metabolism].
119365	GH18_chitinase	2.55e-36	1	153	207	322	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.
119351	GH18_chitolectin_chitotriosidase	2.60e-32	1	163	186	358	This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active chitotriosidases. The conserved domain is an eight-stranded alpha/beta barrel fold belonging to the family 18 glycosyl hydrolases. The fold has a pronounced active-site cleft at the C-terminal end of the beta-barrel. The chitolectins lack a key active site glutamate (the proton donor required for hydrolytic activity) but retain highly conserved residues involved in oligosaccharide binding. Chitotriosidase is a chitinolytic enzyme expressed in maturing macrophages, which suggests that it plays a part in antimicrobial defense. Chitotriosidase hydrolyzes chitotriose, as well as colloidal chitin to yield chitobiose and is therefore considered an exochitinase. Chitotriosidase occurs in two major forms, the large form being converted to the small form by either RNA or post-translational processing. Although the small form, containing the chitinase domain alone, is sufficient for the chitinolytic activity, the additional C-terminal chitin-binding domain of the large form plays a role in processing colloidal chitin. The chitotriosidase gene is nonessential in humans, as about 35% of the population are heterozygous and 6% homozygous for an inactivated form of the gene. HCGP39 is a 39-kDa human cartilage glycoprotein thought to play a role in connective tissue remodeling and defense against pathogens.
395573	Glyco_hydro_18	1.71e-31	1	153	173	307	Glycosyl hydrolases family 18.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start
2.92e-30	1	148	161	308
8.90e-29	1	148	2298	2445
2.76e-28	1	164	203	363
5.43e-27	1	153	701	852
8.39e-27	3	167	478	639

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
4.45e-25	1	167	245	419	Chain A, Glycosyl Hydrolase [Niallia circulans]
9.34e-24	1	164	198	367	Crystal structure of the catalytic domain of chitinase ChiL from Chitiniphilus shinanonensis (CsChiL) [Chitiniphilus shinanonensis],6KST_B Crystal structure of the catalytic domain of chitinase ChiL from Chitiniphilus shinanonensis (CsChiL) [Chitiniphilus shinanonensis],6KXL_A Crystal structure of the catalytic domain of Chitiniphilus shinanonensis chitinase ChiL (CsChiL) complexed with N,N'-diacetylchitobiose [Chitiniphilus shinanonensis],6KXL_B Crystal structure of the catalytic domain of Chitiniphilus shinanonensis chitinase ChiL (CsChiL) complexed with N,N'-diacetylchitobiose [Chitiniphilus shinanonensis]
9.34e-24	1	164	198	367	Crystal structure of D157N mutant of Chitiniphilus shinanonensis chitinase ChiL (CsChiL) complexed with N,N'-diacetylchitobiose [Chitiniphilus shinanonensis],6KXM_B Crystal structure of D157N mutant of Chitiniphilus shinanonensis chitinase ChiL (CsChiL) complexed with N,N'-diacetylchitobiose [Chitiniphilus shinanonensis]
9.34e-24	1	164	198	367	Crystal structure of W50A mutant of Chitiniphilus shinanonensis chitinase ChiL (CsChiL) complexed with N,N'-diacetylchitobiose [Chitiniphilus shinanonensis],6KXN_B Crystal structure of W50A mutant of Chitiniphilus shinanonensis chitinase ChiL (CsChiL) complexed with N,N'-diacetylchitobiose [Chitiniphilus shinanonensis]
2.22e-23	1	170	191	374	Crystal structure of Ostrinia furnacalis Group IV chitinase [Ostrinia furnacalis]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
1.35e-24	1	204	277	489	Chitinase A1 OS=Niallia circulans OX=1397 GN=chiA1 PE=1 SV=1
1.02e-20	1	158	200	352	Endochitinase B OS=Emericella nidulans OX=162425 GN=chiB PE=1 SV=3
1.02e-20	1	158	200	352	Endochitinase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=chiB PE=1 SV=1
1.11e-19	1	163	212	418	Chitinase B OS=Serratia marcescens OX=615 GN=chiB PE=1 SV=1
3.05e-18	1	178	387	596	Chitinase A OS=Pseudoalteromonas piscicida OX=43662 GN=chiA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000070	0.000000

TMHMM Annotations help

There is no transmembrane helices in AMAG_13103-t26_1-p1.