CAZyme Information: AGR95_051390.mRNA-p1

Basic Information

• Species: Histoplasma capsulatum
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
• CAZyme ID: AGR95_051390.mRNA-p1
• CAZy Family: GH3
• CAZyme Description: unspecified product

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
407	HISTO_LF.Contig359|CGC1	46081.50	9.7001

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HcapsulatumG217B	11221	447094	0	11221

• Gene Location: location=HISTO_LF.Contig359:806590-807990(+)

Full Sequence      

MNIYERAIGLATTPEYSRWICPLLLLAEVFLCALIVWKIPYTEIDWSTYMQQVSLFLSGE
RDYALIKGSTGPLVYPAVHVYIYSVLYRICDEGRDIAFAQVVFAILYIATLVIVMWSYRS
ARAPPYLFPLLVLSKRLHSVFLLRLFNDAVATFFLWAAILMMQRRQWTAGVVLWSMGVGV
KMTLLLIAPAVAVIVVLGAGIIKATGLGITALLIQVLLAVPFLQENPSSYMLRAFEFTRQ
FLFKWTVNWRFVGEDTFTSQSFALALLAVHATILALFFVYRWIGPSNASFTQFINNAVHG
KLPPTQISSSFVTTTMLTSFAIGLLCARTLHYQFFAYLSWTTPFLLWKSGFHPVLIYLLW
AAQEWAWNVYPSTTLSSVTVVASISIQVLGTFWNGYRTPVSIKEKNK

Enzyme Prediction     

EC	2.4.1.258:10

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT58	22	377	8.5e-143	0.9945054945054945

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
398745	ALG3	0.0	22	377	1	358	ALG3 protein. The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl pyrophosphate. Whereas early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9GlcNAc2-PP-Dol on the lumenal side use Dol-P-Man. ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS55330.1|GT58	3.62e-285	1	407	1	407
QSS72893.1|GT58	2.09e-284	1	407	1	407
QSS65569.1|GT58	2.89e-235	50	395	1	346
QVM12997.1|GT58	2.07e-174	1	389	1	389
BAE62911.1|GT58	2.86e-174	10	394	10	394

PDB Hits     

AGR95_051390.mRNA-p1 has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q2U6A4|ALG3_ASPOR	5.08e-175	10	394	10	394	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=alg3 PE=3 SV=1
sp|Q4WVG2|ALG3_ASPFU	3.27e-165	1	396	9	404	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=alg3 PE=3 SV=1
sp|A1CBE6|ALG3_ASPCL	3.80e-162	10	394	72	456	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=alg3 PE=3 SV=1
sp|A1DDZ3|ALG3_NEOFI	2.90e-159	1	396	1	396	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=alg3 PE=3 SV=1
sp|A2RA94|ALG3_ASPNC	1.38e-149	10	394	10	390	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=alg3 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000026	0.000002

TMHMM  Annotations     

Start	End
19	41
65	87
96	118
138	160
172	194
204	223
261	283
303	325
337	359
374	396