CAZyme Information: AGR95_036420.mRNA-p1

Basic Information

• Species: Histoplasma capsulatum
• Lineage: Ascomycota; Eurotiomycetes; ; Ajellomycetaceae; Histoplasma; Histoplasma capsulatum
• CAZyme ID: AGR95_036420.mRNA-p1
• CAZy Family: GH16
• CAZyme Description: unspecified product

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
744	HISTO_ZT.Contig174|CGC2	84678.45	4.7667

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_HcapsulatumG217B	11221	447094	0	11221

• Gene Location: location=HISTO_ZT.Contig174:58071-60902(+)

Full Sequence      

VPILAKELGRASNESLLWGPYRPNLYFGVRPRLPKSLIMGLMWANVDEFQNIQEKFRHTC
EQNEGMAGYGWDEYDIRKGGRQTIHDTGNAIDLTIDFIKVPGGGNGGNWGARVKGTPRAD
ASPDQATTVVFYAAIEGLGSLELANEVDALGYKDAVKFTGSTVGLGDFTLDLTRGPESNA
HPPRRHAAYDDKPLDRTIVAGLQVPPDALWNAKSLLFMHMKEEIDATLKEYGTDNPLPPA
QLITIANKPDAGNMYFVQRAFEGSFEVCPRFYYNHLLISLADYGKFDILFSSASSPVPMT
STVLTEEIEPASASFSKKFKEVFPPLSPFNLPKYTEFSKAMFSNLVGGVGYFYGDSVVDR
SNSPEYEEENELFWEETEQARAQVKPSVDGPSELFTSIPSRPFFPRGFLWDEGFHLIPVI
EWDLDLALEITRSWFNLMDDDGWIAREQILGPEARSKVPTEFQFFWFKKTQWGDLKSYDR
EAFSSKEAYRWRGRSIKHILTSGLDDYPRPQPPHPGELHVDLISWMGMMSRAIRRIAETL
EEAEDAKEFAAYETRIIRNIDDLHWDKDAQTFCDATVDDFEEHVHVCHKGYISLFPFMTG
LIPADSPRLGPILDLIQDPKELWSDYGIRSLSKKDEFYGTDENYWRGPIWININYMILKN
LLDVATVPGPHQEQARKMYIQLRQNIVDNVFNQWKETGFAWEQYNPETGAGQRTQHFTGW
TSLVVKMMAMPDLSADHGIRHEEL

Enzyme Prediction     

EC	3.2.1.106:25	3.2.1.-:4

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH63	517	728	1e-36	0.43157894736842106

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397353	Glyco_hydro_63	0.0	299	730	1	494	Glycosyl hydrolase family 63 C-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the C-terminal catalytic domain.
407154	Glyco_hydro_63N	1.42e-119	16	238	1	221	Glycosyl hydrolase family 63 N-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the N-terminal beta sandwich domain.
225942	GDB1	2.84e-07	531	678	428	561	Glycogen debranching enzyme (alpha-1,6-glucosidase) [Carbohydrate transport and metabolism].
236653	PRK10137	1.08e-05	520	728	578	779	alpha-glucosidase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSS68976.1|GH63	0.0	1	744	30	818
QSS63216.1|GH63	0.0	1	744	30	818
QSS50985.1|GH63	0.0	1	744	30	818
QVM12625.1|GH63	0.0	2	735	34	808
BCR88942.1|GH63	0.0	1	744	25	816

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4J5T_A	3.59e-157	6	728	5	800	Crystal structure of Processing alpha-Glucosidase I [Saccharomyces cerevisiae S288C]
5MHF_A	1.30e-129	11	737	32	784	Murine endoplasmic reticulum alpha-glucosidase I with N-9'-methoxynonyl-1-deoxynojirimycin [Mus musculus],5MHF_B Murine endoplasmic reticulum alpha-glucosidase I with N-9'-methoxynonyl-1-deoxynojirimycin [Mus musculus],5MHF_C Murine endoplasmic reticulum alpha-glucosidase I with N-9'-methoxynonyl-1-deoxynojirimycin [Mus musculus],5MHF_D Murine endoplasmic reticulum alpha-glucosidase I with N-9'-methoxynonyl-1-deoxynojirimycin [Mus musculus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|O14255|GCS1_SCHPO	8.16e-215	6	729	32	805	Probable mannosyl-oligosaccharide glucosidase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC6G10.09 PE=3 SV=1
sp|P53008|CWH41_YEAST	3.45e-156	6	728	35	830	Mannosyl-oligosaccharide glucosidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CWH41 PE=1 SV=1
sp|Q80UM7|MOGS_MOUSE	2.88e-131	11	729	87	831	Mannosyl-oligosaccharide glucosidase OS=Mus musculus OX=10090 GN=Mogs PE=1 SV=1
sp|O88941|MOGS_RAT	1.07e-126	11	729	87	831	Mannosyl-oligosaccharide glucosidase OS=Rattus norvegicus OX=10116 GN=Mogs PE=1 SV=1
sp|Q13724|MOGS_HUMAN	3.90e-123	2	729	79	834	Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	CS Position
1.000035	0.000000

TMHMM  Annotations     

There is no transmembrane helices in AGR95_036420.mRNA-p1.