CAZyme Information: AFUB_077400-T-p1

Basic Information

• Species: Aspergillus fumigatus
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus fumigatus
• CAZyme ID: AFUB_077400-T-p1
• CAZy Family: GH7
• CAZyme Description: Ortholog(s) have 1,3-beta-glucanosyltransferase activity and role in fungal-type cell wall organization

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
475	scf_000006_A_fumigatus_A1163|CGC12	51717.74	4.3948

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AfumigatusA1163	10106	451804	199	9907

• Gene Location: location=scf_000006_A_fumigatus_A1163:1511256-1512953(+)

Full Sequence      

MLPTYVRLFTAVCALATTASAVVPIEVKGKDFVNSKTGDRFQILGVDYQPGGSSGFTKDK
DPLSDPDACLRDAALMQRLGVNTIRIYNLSPSLNHDECASIFNAAGIYMILDVNSPLYGG
YLDRTDPESTYNDVYFKQVFGVIEAFKNFPNTLAFFAGNEVINEQSVKNVPTYVRAIQRD
MKDYIAKNLDRSIPVGYSAADIRPILMDTLNYFMCADDANSQSDFFGLNSYSWCGNSSYT
KSGYDVLTKDFADASIPVFFSEYGCNEVQPRYFSEVQALYGQEMTQSFSGGLVYEYTQEE
NDYGLVQINDNGTVTLLVDYDNLMAQYSKLDMSRIQASNTTQTSAKPPKCESSLITNSTF
TDSFDLPKRPSKVQTMIDKGLSDANTGKLVEVKNTDIKQKIYNANGEEITGIKLSILASG
ESNTPGAHSSGSTSGSSSSGGSSSSSSDKESAAGTISVPFVGLLSAASFMAFFML

Enzyme Prediction     

EC	2.4.1.-:8

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH72	20	329	1.4e-127	0.9871794871794872

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397351	Glyco_hydro_72	4.10e-157	14	331	1	315	Glucanosyltransferase. This is a family of glycosylphosphatidylinositol-anchored beta(1-3)glucanosyltransferases. The active site residues in the Aspergillus fumigatus example are the two glutamate residues at 160 and 261.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AAF40139.1|GH72|2.4.1.-	0.0	1	475	1	475
EAL88984.1|GH72	0.0	1	475	1	475
BAE59016.1|GH72	9.37e-248	5	467	5	465
QMW29276.1|GH72	1.19e-247	5	467	2	462
QMW41348.1|GH72	1.19e-247	5	467	2	462

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2W62_A	6.14e-78	25	331	36	344	Saccharomyces cerevisiae Gas2p in complex with laminaripentaose [Saccharomyces cerevisiae],2W63_A Saccharomyces Cerevisiae Gas2p In Complex With Laminaritriose And Laminaritetraose [Saccharomyces cerevisiae],5O9O_A Crystal structure of ScGas2 in complex with compound 7. [Saccharomyces cerevisiae S288C],5O9P_A Crystal structure of Gas2 in complex with compound 10 [Saccharomyces cerevisiae S288C],5O9Q_A Crystal structure of ScGas2 in complex with compound 6 [Saccharomyces cerevisiae S288C],5O9R_A Crystal structure of ScGas2 in complex with compound 9 [Saccharomyces cerevisiae S288C],5O9Y_A Crystal structure of ScGas2 in complex with compound 11 [Saccharomyces cerevisiae S288C],5OA2_A Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA2_B Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA2_C Crystal structure of ScGas2 in complex with compound 8 [Saccharomyces cerevisiae S288C],5OA6_A Crystal structure of ScGas2 in complex with compound 12 [Saccharomyces cerevisiae S288C]
2W61_A	1.70e-77	25	331	36	344	Saccharomyces cerevisiae Gas2p apostructure (E176Q mutant) [Saccharomyces cerevisiae]
5FIH_A	1.70e-77	25	331	36	344	SACCHAROMYCES CEREVISIAE GAS2P (E176Q MUTANT) IN COMPLEX WITH LAMINARITETRAOSE AND LAMINARIPENTAOSE [Saccharomyces cerevisiae]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P0C954|GEL2_ASPFU	0.0	1	475	1	475	1,3-beta-glucanosyltransferase gel2 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=gel2 PE=3 SV=1
sp|B0Y8H9|GEL2_ASPFC	0.0	1	475	1	475	1,3-beta-glucanosyltransferase gel2 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=gel2 PE=1 SV=1
sp|Q03655|GAS3_YEAST	3.36e-120	8	390	8	412	Probable 1,3-beta-glucanosyltransferase GAS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GAS3 PE=1 SV=1
sp|Q08271|GAS4_YEAST	9.72e-106	20	350	21	354	1,3-beta-glucanosyltransferase GAS4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GAS4 PE=1 SV=1
sp|Q08193|GAS5_YEAST	9.89e-100	14	330	19	330	1,3-beta-glucanosyltransferase GAS5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GAS5 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000316	0.999663	CS pos: 21-22. Pr: 0.9726

TMHMM  Annotations     

There is no transmembrane helices in AFUB_077400-T-p1.