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CAZyme Information: AFUB_070730-T-p1

You are here: Home > Sequence: AFUB_070730-T-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Aspergillus fumigatus
Lineage Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus fumigatus
CAZyme ID AFUB_070730-T-p1
CAZy Family GH5
CAZyme Description Ortholog(s) have exo-alpha-sialidase activity
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
406 scf_000005_A_fumigatus_A1163|CGC13 44413.75 9.8016
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_AfumigatusA1163 10106 451804 199 9907
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.18:1 3.2.1.-:1

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH33 54 390 1.4e-59 0.9327485380116959

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
271229 Sialidase 2.20e-126 35 396 1 361
sialidases/neuraminidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed beta-propeller fold. This hierarchy includes eubacterial, eukaryotic, and viral sialidases.
271234 Sialidase_non-viral 1.37e-65 54 396 10 339
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
404074 BNR_2 7.41e-11 117 370 27 279
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
1.66e-310 1 406 1 406
2.34e-226 21 406 21 409
3.67e-208 33 406 2 376
1.27e-201 21 406 34 424
6.46e-192 21 406 18 403

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6.11e-311 1 406 17 422
Structural evaluation the Y358H mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293],4M4N_B Structural evaluation the Y358H mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293]
1.23e-310 1 406 17 422
Structural evaluation R171L mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293],4M4V_B Structural evaluation R171L mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293]
1.75e-310 1 406 17 422
Structural evaluation D84A mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293],4M4U_B Structural evaluation D84A mutant of the aspergillus fumigatus kdnase (sialidase) [Aspergillus fumigatus Af293]
1.16e-297 21 406 1 386
The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZI_B The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZJ_A The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZJ_B The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZK_A The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293],2XZK_B The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural And Mechanistic Insights [Aspergillus fumigatus Af293]
4.33e-293 21 406 1 386
Crystal structure of Aspergillus fumigatus sialidase [Aspergillus fumigatus],2XCY_B Crystal structure of Aspergillus fumigatus sialidase [Aspergillus fumigatus]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2.95e-311 1 406 1 406
Exo-alpha-sialidase OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=AFUA_4G13800 PE=1 SV=2
9.43e-219 8 406 7 408
Exo-alpha-sialidase ARB_03431 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=ARB_03431 PE=1 SV=1
1.06e-20 54 400 63 401
Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1
1.37e-12 57 375 202 527
Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2
1.79e-10 21 261 313 616
Sialidase A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=nanA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000236 0.999711 CS pos: 20-21. Pr: 0.9785

TMHMM  Annotations      help

There is no transmembrane helices in AFUB_070730-T-p1.