CAZyme Information: AFUB_061710-T-p1

Basic Information

• Species: Aspergillus fumigatus
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus fumigatus
• CAZyme ID: AFUB_061710-T-p1
• CAZy Family: GH43
• CAZyme Description: Protein of unknown function

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
456	scf_000004_A_fumigatus_A1163|CGC14	51346.13	5.3312

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AfumigatusA1163	10106	451804	199	9907

• Gene Location: location=scf_000004_A_fumigatus_A1163:3574560-3575930(+)

Full Sequence      

MKLYLLSLLPSLFTTTVLSYPAPSNSGTTSPRLAIDFYKRQCDCYVVSGSETVYFENYAF
WDFRKIPLPRYDSNGSKVRIKRRSYTRSRADRTDKDEGDNEEGKVGIEENGDNEENLNGE
DNADDGENDYNGMKAVGEGLDLGTLPFSHTAFARDWKPQEWHRKSNKYGPLPIINSPENI
FFASNTLYTNDAESTHLVLRTTRFPNHTATAELEYHLRNIFHCSLRVRMRVMTVGSVNRE
PMLYGRPVLKGNPTSQSVVPIGACAGIFTYRSSTCESDIEILTSDPTNIVRYANQPDYDP
ITDAMIPGAASIGKLSQPWTNPTTHRVDWLHNITNWYADGEIKASNTYHVPDQPSMMAIN
LWSNGGEWTGEMPVGQSAYIGIEWIEVAYNTSTEVNGIPSDTVPFPSHKHRPFARSPELG
SELDHETSAGEVEYIQRRDAARKCLRPCFLDDVRGP

Enzyme Prediction     

No EC number prediction in AFUB_061710-T-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH16	154	387	3.1e-74	0.9907407407407407

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
185683	Glyco_hydrolase_16	1.86e-37	146	387	2	209	glycosyl hydrolase family 16. The O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A glycosyl hydrolase classification system based on sequence similarity has led to the definition of more than 95 different families inlcuding glycosyl hydrolase family 16. Family 16 includes lichenase, xyloglucan endotransglycosylase (XET), beta-agarase, kappa-carrageenase, endo-beta-1,3-glucanase, endo-beta-1,3-1,4-glucanase, and endo-beta-galactosidase, all of which have a conserved jelly roll fold with a deep active site channel harboring the catalytic residues.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCS29547.1|GH16_22	4.79e-96	21	454	25	383
CAK42110.1|GH16_22	4.67e-93	1	451	1	413
BCR99502.1|GH16_22	1.03e-92	36	451	30	405
BCS11802.1|GH16_22	1.03e-92	36	451	30	405
BCR90028.1|GH16_22	1.81e-90	22	454	23	433

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
1GBG_A	2.07e-08	238	385	64	209	Bacillus Licheniformis Beta-Glucanase [Bacillus licheniformis]
3O5S_A	1.21e-07	262	385	110	233	Crystal Structure of the endo-beta-1,3-1,4 glucanase from Bacillus subtilis (strain 168) [Bacillus subtilis]
1AXK_A	3.74e-07	324	394	88	160	Engineered Bacillus Bifunctional Enzyme Gluxyn-1 [Bacillus subtilis],1AXK_B Engineered Bacillus Bifunctional Enzyme Gluxyn-1 [Bacillus subtilis]
1CPN_A	1.71e-06	324	392	88	158	NATIVE-LIKE IN VIVO FOLDING OF A CIRCULARLY PERMUTED JELLYROLL PROTEIN SHOWN BY CRYSTAL STRUCTURE ANALYSIS [Paenibacillus macerans]
1MAC_A	3.24e-06	324	390	144	212	Crystal Structure And Site-Directed Mutagenesis Of Bacillus Macerans Endo-1,3-1,4-Beta-Glucanase [Paenibacillus macerans],1MAC_B Crystal Structure And Site-Directed Mutagenesis Of Bacillus Macerans Endo-1,3-1,4-Beta-Glucanase [Paenibacillus macerans]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|P27051|GUB_BACLI	4.87e-07	238	370	93	223	Beta-glucanase OS=Bacillus licheniformis OX=1402 GN=bg1 PE=1 SV=1
sp|P04957|GUB_BACSU	6.48e-07	262	385	114	237	Beta-glucanase OS=Bacillus subtilis (strain 168) OX=224308 GN=bglS PE=1 SV=2
sp|P45797|GUB_PAEPO	6.61e-06	262	390	110	238	Beta-glucanase OS=Paenibacillus polymyxa OX=1406 GN=gluB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000396	0.999578	CS pos: 19-20. Pr: 0.9815

TMHMM  Annotations     

There is no transmembrane helices in AFUB_061710-T-p1.