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CAZyme Information: AFUB_032460-T-p1

You are here: Home > Sequence: AFUB_032460-T-p1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Aspergillus fumigatus
Lineage Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus fumigatus
CAZyme ID AFUB_032460-T-p1
CAZy Family GH135
CAZyme Description Has domain(s) with predicted transferase activity, transferring hexosyl groups activity and endoplasmic reticulum membrane localization
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
440 scf_000002_A_fumigatus_A1163|CGC29 50468.98 9.6823
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_AfumigatusA1163 10106 451804 199 9907
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.265:13 2.4.1.-:9

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT57 2 432 1.2e-131 0.8482328482328483

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
397324 Alg6_Alg8 1.50e-152 3 430 73 472
ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
9.66e-261 1 438 88 505
3.89e-257 1 439 83 503
1.58e-256 1 439 83 503
2.00e-256 1 439 128 548
2.00e-256 1 439 128 548

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4.73e-14 17 314 159 410
Cryo-EM structure of yeast ALG6 in complex with 6AG9 Fab and Dol25-P-Glc [Saccharomyces cerevisiae],6SNI_X Cryo-EM structure of nanodisc reconstituted yeast ALG6 in complex with 6AG9 Fab [Saccharomyces cerevisiae]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2.80e-257 1 439 83 503
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=alg8 PE=3 SV=1
4.08e-235 1 440 83 501
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase OS=Coccidioides immitis (strain RS) OX=246410 GN=ALG8 PE=3 SV=1
4.38e-227 1 408 83 470
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=alg8 PE=3 SV=1
5.81e-205 1 439 83 504
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=alg-8 PE=3 SV=2
1.67e-203 1 439 83 500
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase OS=Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) OX=229533 GN=ALG8 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
1.000004 0.000021

TMHMM  Annotations      download full data without filtering help

Start End
67 89
119 141
162 184
278 300
321 343
353 370
383 405
415 437