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CAZyme Information: AEO61974.1

You are here: Home > Sequence: AEO61974.1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Thermothelomyces thermophilus
Lineage Ascomycota; Sordariomycetes; ; Chaetomiaceae; Thermothelomyces; Thermothelomyces thermophilus
CAZyme ID AEO61974.1
CAZy Family GT4
CAZyme Description glycosyltransferase family 4 protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
578 63673.44 8.4502
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_TthermophilusATCC42464 9292 573729 195 9097
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.131:1

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT4 379 535 3.1e-25 0.9

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
340835 GT4_ALG11-like 0.0 129 560 1 419
alpha-1,2-mannosyltransferase ALG11 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides.
215511 PLN02949 8.96e-147 131 571 36 460
transferase, transferring glycosyl groups
406369 ALG11_N 4.78e-137 129 340 1 208
ALG11 mannosyltransferase N-terminus.
223515 RfaB 2.23e-26 300 572 129 381
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
395425 Glycos_transf_1 3.70e-24 381 552 2 158
Glycosyl transferases group 1. Mutations in this domain of PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
0.0 1 578 1 578
5.48e-287 28 572 7 547
1.11e-275 2 570 7 567
3.11e-273 24 569 3 556
3.11e-273 24 569 3 556

PDB Hits      help

AEO61974.1 has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
9.73e-288 28 572 7 547
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=alg-11 PE=3 SV=1
1.58e-129 131 559 57 454
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=alg11 PE=3 SV=1
2.10e-111 130 569 64 491
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Mus musculus OX=10090 GN=Alg11 PE=2 SV=1
1.44e-107 131 573 63 499
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Danio rerio OX=7955 GN=alg11 PE=2 SV=2
1.26e-106 130 568 64 490
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase OS=Homo sapiens OX=9606 GN=ALG11 PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI CS Position
1.000058 0.000006

TMHMM  Annotations      download full data without filtering help

Start End
31 53