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CAZyme Information: AEO59823.1

You are here: Home > Sequence: AEO59823.1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Thermothelomyces thermophilus
Lineage Ascomycota; Sordariomycetes; ; Chaetomiaceae; Thermothelomyces; Thermothelomyces thermophilus
CAZyme ID AEO59823.1
CAZy Family GH7
CAZyme Description glycoside hydrolase family 61 protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
254 28369.23 4.5672
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_TthermophilusATCC42464 9292 573729 195 9097
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in AEO59823.1.

CAZyme Signature Domains help

Family Start End Evalue family coverage
AA9 7 235 6.3e-53 0.9863636363636363

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
410622 LPMO_AA9 2.31e-66 19 252 1 216
lytic polysaccharide monooxygenase (LPMO) auxiliary activity family 9 (AA9). AA9 proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs) involved in the cleavage of cellulose chains with oxidation of carbons C1 and/or C4 and C6. Activities include lytic cellulose monooxygenase (C1-hydroxylating) (EC 1.14.99.54) and lytic cellulose monooxygenase (C4-dehydrogenating) (EC 1.14.99.56). The family used to be called GH61 because weak endoglucanase activity had been demonstrated in some family members.
397484 Glyco_hydro_61 6.91e-61 20 235 1 206
Glycosyl hydrolase family 61. Although weak endoglucanase activity has been demonstrated in several members of this family, they lack the clustered conserved catalytic acidic amino acids present in most glycoside hydrolases. Many members of this family lack measurable cellulase activity on their own, but enhance the activity of other cellulolytic enzymes. They are therefore unlikely to be true glycoside hydrolases. The subsrate-binding surface of this family is a flat Ig-like fold.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
8.54e-200 1 254 1 254
6.16e-142 1 254 1 250
4.36e-105 35 254 35 255
4.06e-102 10 225 14 230
4.06e-102 10 225 14 230

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
7.11e-56 19 254 1 225
Crystal structure of HiLPMO9B [Heterobasidion irregulare TC 32-1],5NNS_B Crystal structure of HiLPMO9B [Heterobasidion irregulare TC 32-1]
2.25e-39 20 254 2 227
Crystal Structure of a Cellulose-active Polysaccharide Monooxygenase from M. thermophila (MtPMO3*) [Thermothelomyces thermophilus ATCC 42464],5UFV_B Crystal Structure of a Cellulose-active Polysaccharide Monooxygenase from M. thermophila (MtPMO3*) [Thermothelomyces thermophilus ATCC 42464],5UFV_C Crystal Structure of a Cellulose-active Polysaccharide Monooxygenase from M. thermophila (MtPMO3*) [Thermothelomyces thermophilus ATCC 42464],5UFV_D Crystal Structure of a Cellulose-active Polysaccharide Monooxygenase from M. thermophila (MtPMO3*) [Thermothelomyces thermophilus ATCC 42464],5UFV_E Crystal Structure of a Cellulose-active Polysaccharide Monooxygenase from M. thermophila (MtPMO3*) [Thermothelomyces thermophilus ATCC 42464],5UFV_F Crystal Structure of a Cellulose-active Polysaccharide Monooxygenase from M. thermophila (MtPMO3*) [Thermothelomyces thermophilus ATCC 42464]
4.93e-30 20 252 2 223
Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases (PMO-3) [Neurospora crassa OR74A]
6.92e-30 20 252 2 223
Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases (PMO-3) [Neurospora crassa OR74A]
4.92e-29 19 254 1 222
Chain A, LPMO9F [Malbranchea cinnamomea]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.96e-54 8 252 19 254
Cellulose-growth-specific protein OS=Agaricus bisporus OX=5341 GN=cel1 PE=3 SV=1
1.00e-29 18 254 19 245
Polysaccharide monooxygenase Cel61a OS=Myceliophthora thermophila (strain ATCC 42464 / BCRC 31852 / DSM 1799) OX=573729 GN=Cel61a PE=1 SV=1
1.11e-23 5 254 6 249
Endoglucanase-7 OS=Hypocrea jecorina (strain QM6a) OX=431241 GN=cel61b PE=1 SV=3
5.02e-21 4 254 7 248
Endoglucanase-4 OS=Hypocrea jecorina OX=51453 GN=cel61a PE=1 SV=1
3.48e-12 11 254 8 237
Probable endo-beta-1,4-glucanase D OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=eglD PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000195 0.999777 CS pos: 20-21. Pr: 0.8755

TMHMM  Annotations      help

There is no transmembrane helices in AEO59823.1.