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CAZyme Information: AEO59361.1

You are here: Home > Sequence: AEO59361.1

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Thermothelomyces thermophilus
Lineage Ascomycota; Sordariomycetes; ; Chaetomiaceae; Thermothelomyces; Thermothelomyces thermophilus
CAZyme ID AEO59361.1
CAZy Family GH5
CAZyme Description glycoside hydrolase family 7 protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
456 CP003005|CGC6 49058.77 4.5634
Genome Property
Genome Version/Assembly ID Genes Strain NCBI Taxon ID Non Protein Coding Genes Protein Coding Genes
FungiDB-61_TthermophilusATCC42464 9292 573729 195 9097
Gene Location

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.4:7

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH7 26 418 3.2e-153 0.983132530120482

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
395677 Glyco_hydro_7 0.0 28 417 7 434
Glycosyl hydrolase family 7.
153432 GH7_CBH_EG 0.0 28 412 2 386
Glycosyl hydrolase family 7. Glycosyl hydrolase family 7 contains eukaryotic endoglucanases (EGs) and cellobiohydrolases (CBHs) that hydrolyze glycosidic bonds using a double-displacement mechanism. This leads to a net retention of the conformation at the anomeric carbon. Both enzymes work synergistically in the degradation of cellulose,which is the main component of plant cell wall, and is composed of beta-1,4 linked glycosyl units. EG cleaves the beta-1,4 linkages of cellulose and CBH cleaves off cellobiose disaccharide units from the reducing end of the chain. In general, the O-glycosyl hydrolases are a widespread group of enzymes that hydrolyze the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A glycosyl hydrolase classification system based on sequence similarity has led to the definition of more than 95 different families inlcuding glycoside hydrolase family 7.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
0.0 1 456 1 456
0.0 1 456 1 456
1.80e-250 1 423 1 420
1.80e-250 1 423 1 420
3.42e-224 10 424 7 419

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3.64e-216 23 419 3 399
Chain AAA, Endoglucanase 1 [Humicola insolens],6YOZ_BBB Chain BBB, Endoglucanase 1 [Humicola insolens]
3.92e-216 23 419 3 399
Chain AAA, Endoglucanase 1 [Humicola insolens]
6.82e-216 23 418 3 398
HUMICOLA INSOLENS ENDOCELLULASE EGI NATIVE STRUCTURE [Humicola insolens],2A39_B HUMICOLA INSOLENS ENDOCELLULASE EGI NATIVE STRUCTURE [Humicola insolens]
2.26e-215 23 419 3 399
Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7B E197A and E197S glycosynthase mutants [Humicola insolens],1OJJ_A Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7BE197A and E197S glycosynthase mutants [Humicola insolens],1OJJ_B Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7BE197A and E197S glycosynthase mutants [Humicola insolens],1OJK_A Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7BE197A and E197S glycosynthase mutants [Humicola insolens],1OJK_B Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7BE197A and E197S glycosynthase mutants [Humicola insolens]
3.20e-215 23 419 3 399
Humicola insolens Endocellulase Cel7B (EG 1) E197A Mutant [Humicola insolens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1.44e-223 1 419 1 419
Endoglucanase EG-1 OS=Humicola grisea var. thermoidea OX=5528 GN=EG-1 PE=3 SV=1
4.97e-216 21 419 1 399
Endoglucanase 1 OS=Humicola insolens OX=34413 GN=CEL7B PE=1 SV=1
1.20e-181 5 419 2 418
Endoglucanase 1 OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=egl1 PE=1 SV=1
1.43e-181 10 425 8 421
Endoglucanase type C OS=Fusarium oxysporum OX=5507 PE=1 SV=1
1.56e-146 10 418 8 415
Probable endo-beta-1,4-glucanase celB OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=celB PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI CS Position
0.000222 0.999738 CS pos: 20-21. Pr: 0.9751

TMHMM  Annotations      help

There is no transmembrane helices in AEO59361.1.