CAZyme Information: ACLA_096520-t26_1-p1

Basic Information

• Species: Aspergillus clavatus
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus clavatus
• CAZyme ID: ACLA_096520-t26_1-p1
• CAZy Family: GT59
• CAZyme Description: mannosyl-oligosaccharide glucosidase, putative

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
822	DS027058|CGC3	92512.34	4.6804

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AclavatusNRRL1	9428	344612	287	9141

• Gene Location: location=DS027058:399916-402745(+)

Full Sequence      

MRLLKLWFLAAPLLHNAVVSASQASAEDDISVLTTETAKANNDSLLWGPYKPNLYFGVRP
RIPNSLSAGLMWAKVDDYSTAQNNFRHTCEQNEGMAGYGWDEYDIRKGGRQTIHDTGNSL
DLTIDFVKVPGGQHGGSWAARVKGVPRDDAPPDQPTSVVFYASLEGLGNLGVTTESEPLG
FAGDVKLAGYTSELGDFSIDVTAGPESNGHPEIDHPAHEDKPLDRTLVSSSTIAPENLWQ
AKAIMFGQMKSEVDEIIQKYGAENPPPPPQVFTIKNAPGEGNIHFVQKVFKGPFEFDILF
NSGSSSNPVTTESLTKEIASVSELFSERFDKVIPPQSPFQTAEYSEFSKAMLSNLVGGIG
FFHGDDVVDRSGAPEYDEENEGFWEETAEARARAQPVLEGPKDLFTCVPSRPFFPRGFLW
DEGFHLIPVIEWDTDLALEIVKSWLHLMDDDGWIAREQILGAEARSKVPPEFTVQYPHYA
NPPTLFMVLESFLDKLEAGRDSSSQSSTSQGVSDNLRSAYVQHPELGEAYIRSIYPLLRK
HYFWYRTTQKGDIKSYDREAFSTKEAYRWRGRSVQHILTSGLDDYPRPQPPHPGELHVDL
ISWMGMMTRAMRRIAEFVGETEDAQEFRGYETAIARNIEDLHWDDQAQTYCDATIDEYEE
SVHVCHKGYISLFPFLTGILGPDSPRLKAVLDLISDPEELWSDYGIRSLSKKDEFYGTAE
NYWRSPIWMPINYLVVKNLHDVATTPGPHQGQAREMYSSLRKNLVENVFRQWKDTGFAWE
QYNPETGKGQRTQHFTGWTSMVVKIMTMPDLPATERASHDEL

Enzyme Prediction     

EC	3.2.1.106:25	3.2.1.-:4

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH63	595	806	3.4e-34	0.43157894736842106

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
397353	Glyco_hydro_63	0.0	310	808	2	494	Glycosyl hydrolase family 63 C-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the C-terminal catalytic domain.
407154	Glyco_hydro_63N	3.52e-132	45	267	1	221	Glycosyl hydrolase family 63 N-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the N-terminal beta sandwich domain.
225942	GDB1	8.77e-08	528	756	358	561	Glycogen debranching enzyme (alpha-1,6-glucosidase) [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AAR23808.1|GH63	0.0	8	822	8	822
QRD84190.1|GH63	0.0	1	822	1	817
UDD57712.1|GH63	0.0	1	822	1	817
CAL00956.1|GH63	0.0	1	822	1	822
QMW44709.1|GH63	0.0	1	822	1	829

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4J5T_A	2.98e-179	36	806	6	800	Crystal structure of Processing alpha-Glucosidase I [Saccharomyces cerevisiae S288C]
5MHF_A	3.24e-141	45	806	37	775	Murine endoplasmic reticulum alpha-glucosidase I with N-9'-methoxynonyl-1-deoxynojirimycin [Mus musculus],5MHF_B Murine endoplasmic reticulum alpha-glucosidase I with N-9'-methoxynonyl-1-deoxynojirimycin [Mus musculus],5MHF_C Murine endoplasmic reticulum alpha-glucosidase I with N-9'-methoxynonyl-1-deoxynojirimycin [Mus musculus],5MHF_D Murine endoplasmic reticulum alpha-glucosidase I with N-9'-methoxynonyl-1-deoxynojirimycin [Mus musculus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|O14255|GCS1_SCHPO	5.98e-252	30	807	27	805	Probable mannosyl-oligosaccharide glucosidase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC6G10.09 PE=3 SV=1
sp|P53008|CWH41_YEAST	1.34e-179	24	806	22	830	Mannosyl-oligosaccharide glucosidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CWH41 PE=1 SV=1
sp|Q80UM7|MOGS_MOUSE	2.08e-142	45	806	92	830	Mannosyl-oligosaccharide glucosidase OS=Mus musculus OX=10090 GN=Mogs PE=1 SV=1
sp|Q13724|MOGS_HUMAN	2.73e-135	45	806	94	833	Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5
sp|O88941|MOGS_RAT	4.98e-135	47	806	94	830	Mannosyl-oligosaccharide glucosidase OS=Rattus norvegicus OX=10116 GN=Mogs PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000441	0.999546	CS pos: 21-22. Pr: 0.9663

TMHMM  Annotations     

There is no transmembrane helices in ACLA_096520-t26_1-p1.