CAZyme Information: ACLA_075630-t26_1-p1

Basic Information

• Species: Aspergillus clavatus
• Lineage: Ascomycota; Eurotiomycetes; ; Aspergillaceae; Aspergillus; Aspergillus clavatus
• CAZyme ID: ACLA_075630-t26_1-p1
• CAZy Family: GH76
• CAZyme Description: DUF1237 domain protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
535	DS027045|CGC4	59088.70	5.4574

Genome Property

Genome Version/Assembly ID	Genes	Strain NCBI Taxon ID	Non Protein Coding Genes	Protein Coding Genes
FungiDB-61_AclavatusNRRL1	9428	344612	287	9141

• Gene Location: location=DS027045:2370951-2372708(+)

Full Sequence      

MTFSSALFVALTVGLQIHSTEGLRDEPAILRRACPDYLSYSTVPHAPYSGGPLNLPFQRP
AAECRTFSSPAVEKVIEDVTSRMVDKDLAQLFRNAFPNTLDTTVRWHTDGSTSSRKAKKD
SAQWQGPQSFIVTGDINAEWLRDSTNQLSGYQVLAKKDKALYNLILGAINTQAEFVIQSP
YCNAFQPPPPSGLQSASNGQDDKVHPAYEPSVVFECKYELDSLANFLALGTQFYENTGST
DFLTDRWYKALDTLLKILDVQSRPTFNAQNEFETNQYTFQRTTTIGTETLNLAGVGNPLN
DGTGLIRSAFRPSDDATILGFFIPPNAMMAVQLEKTANVIKAAGGSLDLIENLRQRGDKL
GQAVREHGIVHHSKYGDVFAFEVDGYGSRILMDDANVPSLLSLPLLGYVDQKDPVYQNTR
KMILDKGGNPYYLTGTEFHGIGGPHIGLQNAWPMSLLVQAMTSDSETEIMEAVNLVRNSS
LLGLVHESINVNNIKDYTRPWFAWANSVFAQTILKIAAEKPHLIFGEGAKPYIIQ

Enzyme Prediction     

No EC number prediction in ACLA_075630-t26_1-p1.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH125	85	514	3.8e-163	0.9975124378109452

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
399660	Glyco_hydro_125	0.0	85	514	1	416	Metal-independent alpha-mannosidase (GH125). This family, which contains bacterial and fungal glycoside hydrolases, is also known as GH125. They function as metal-independent alpha-mannosidases, with specificity for alpha-1,6-linked non-reducing terminal mannose residues. Structurally this family is part of the 6 hairpin glycosidase superfamily.
226068	COG3538	4.14e-155	64	523	2	429	Meiotically up-regulated gene 157 (Mug157) protein (function unknown) [Function unknown].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QRD90853.1|GH125	0.0	4	535	5	537
QMW43832.1|GH125	0.0	4	535	5	537
QMW31801.1|GH125	0.0	4	535	5	537
UDD60757.1|GH125	0.0	4	535	5	537
BAE61251.1|GH125	0.0	4	535	5	537

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2P0V_A	4.78e-97	54	519	38	471	Crystal structure of BT3781 protein from Bacteroides thetaiotaomicron, Northeast Structural Genomics Target BtR58 [Bacteroides thetaiotaomicron VPI-5482],2P0V_B Crystal structure of BT3781 protein from Bacteroides thetaiotaomicron, Northeast Structural Genomics Target BtR58 [Bacteroides thetaiotaomicron VPI-5482]
3ON6_A	6.53e-96	54	519	18	451	Crystal structure of an exo-alpha-1,6-mannosidase (bacova_03626) from bacteroides ovatus at 1.70 a resolution [Bacteroides ovatus ATCC 8483],3ON6_B Crystal structure of an exo-alpha-1,6-mannosidase (bacova_03626) from bacteroides ovatus at 1.70 a resolution [Bacteroides ovatus ATCC 8483]
3P2C_A	3.13e-90	59	519	21	453	Crystal structure of an exo-alpha-1,6-mannosidase (bacova_03347) from bacteroides ovatus at 1.60 a resolution [Bacteroides ovatus ATCC 8483],3P2C_B Crystal structure of an exo-alpha-1,6-mannosidase (bacova_03347) from bacteroides ovatus at 1.60 a resolution [Bacteroides ovatus ATCC 8483]
6RQK_A	7.26e-79	72	520	12	426	Crystal structure of GH125 1,6-alpha-mannosidase from Clostridium perfringens in complex with mannoimidazole [Clostridium perfringens str. 13],6RQK_B Crystal structure of GH125 1,6-alpha-mannosidase from Clostridium perfringens in complex with mannoimidazole [Clostridium perfringens str. 13]
5M7I_A	3.98e-78	72	520	12	426	Crystal structure of GH125 1,6-alpha-mannosidase mutant from Clostridium perfringens in complex with 1,6-alpha-mannobiose [Clostridium perfringens str. 13],5M7Y_A Crystal structure of GH125 1,6-alpha-mannosidase mutant from Clostridium perfringens in complex with 1,6-alpha-mannotriose [Clostridium perfringens str. 13]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
sp|Q10449|MU157_SCHPO	2.93e-184	32	524	25	504	Meiotically up-regulated gene 157 protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mug157 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	CS Position
0.000211	0.999766	CS pos: 22-23. Pr: 0.9771

TMHMM  Annotations     

There is no transmembrane helices in ACLA_075630-t26_1-p1.