Browse anti-prokaryotic immune system families by CLAN ID
| AD families | AD genes | Defense system | CLAN ID | Phages/MGEs | References | Description |
|---|---|---|---|---|---|---|
| APIS002 | vs.4 | cyclic oligonucleotide-based antiphage signaling system (CBASS) | CLAN056 | T4 of E. coli | PMID:36848932 | Vs.4 antagonized cGAS signaling by binding tightly to cGAMP (dissociation constant of approximately 30 nM) and sequestering it; Bioinformatic analyses identified 198 homologues of Vs.4 in diverse phages; belongs to PHROG 717. |